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WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.
BEIJING, April 10 (Xinhua) -- While advocating Internet freedom worldwide, the U.S. imposes fairly strict restriction on cyberspace on its own territory, said the Human Rights Record of the United States in 2010 issued by the Information Office of China's State Council Sunday.The United States applies double standards on Internet freedom by requesting unrestricted "Internet freedom" in other countries, which becomes an important diplomatic tool for the U.S. to impose pressure and seek hegemony, and imposing strict restriction within its own territory, the report said.According to the report, on June 24, 2010, the U.S. Senate Committee on Homeland Security and Governmental Affairs approved the Protecting Cyberspace as a National Asset Act, which will give the federal government "absolute power" to shut down the Internet under a declared national emergency.

BEIJING, Feb. 3 (Xinhua) -- Chinese Foreign Ministry said here Thursday that almost all Chinese travellers stranded in Egypt had returned home by planes sent by the government.A total of 1,848 Chinese, including those from Hong Kong, Macao and Taiwan, had been flown back by Thursday afternoon, the ministry said in a statement.The Chinese government has organized eight flights from four Chinese airline companies to Egypt since Jan. 31.The last two planes, belonging to China Eastern Airlines, returned to Beijing from Egypt Thursday, bringing back a total of 431 Chinese citizens, according to the ministry.
BEIJING, Feb.9 (Xinhua) -- China's State Council, the nation's cabinet, pledged Wednesday to step up efforts to boost grain production as relentless droughts continue to wreak havoc in north China's wheat growing regions.To encourage farmers to plant more and increase production, China will increase minimum purchase prices for grain produced in 2011 by up to 21.9 percent from that in 2010, according to a statement released after a State Council executive meeting presided over by Premier Wen Jiabao.The purchasing prices for japonica rice will rise 21.9 percent to 128 yuan (19.4 U.S. dollars) per 50 kilograms this year, while prices for early and middle-late indica rice will increase 9.7 percent and 10.3 percent to 102 yuan and 107 yuan per 50 kilograms respectively.Further, the central government will allocate 1.2 billion yuan to subsidize the purchase of anti-drought technologies for winter wheat-growing regions.According to the statement, the government has already allocated 4 billion yuan for rural water conservation projects and another 2 billion yuan will be allocated for farm irrigation systems and safe drinking water projects.The government had also pledged to fund 2,000 professional groups in insect-prevention in the worst-hit counties, the statement said.China's main wheat-growing regions, including Shandong, Henan, Hebei, Anhui, Shanxi, Shaanxi, Gansu and Jiangsu provinces, have been plagued by ongoing droughts since last year.
SYDNEY, Jan. 25 (Xinhua) -- Huawei Technologies, on Monday asked a U.S. District Court to prevent Motorola from illegally transferring Huawei's intellectual property (IP) to Nokia Siemens Networks ("NSN"), officials of Huawei told Xinhua in Sydney, Australia on Tuesday.As a leading player in providing next generation telecommunications network solutions, Huawei took this action as NSN seeks to complete its 1.2 billion U.S. dollars acquisition of Motorola's wireless network business.Since 2000, Huawei and Motorola have had a cooperative relationship in the radio access network and core network businesses, where Motorola has resold Huawei wireless network products to customers under the Motorola name. During this period, Motorola was provided with products and confidential Huawei IP developed by Huawei's team of more than 10,000 engineers.Since the July 2010 announcement by NSN of its purchase of Motorola's wireless network business, Huawei has tried to ensure that Motorola does not transfer this confidential information to NSN.According to officials of Huawei, Motorola's failure to adopt measures sufficient to ensure that Huawei's proprietary information remains confidential has compelled the company to file for the appropriate legal protection of its rights.The officials said Huawei respects the rights of intellectual property holders and is equally committed to the protection of its own innovations and intellectual property.Nearly half of Huawei's 100,000 plus employees are engaged in research and development and Huawei allocates an average of 10 percent of all revenues to R&D annually. By the end of 2010, Huawei had applied for 49,040 essential patents on a global basis.
来源:资阳报