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LOS ANGELES, April 4 (Xinhua) -- A woman's breast milk cells may be used to predict cancer in future research, according to a study published by HealthDay News on Monday.In the study, researchers at the University of Massachusetts in Amherst collected breast milk from 271 women in the United States. All had either undergone a biopsy of the breast to check for cancer, or were scheduled for one.The researchers evaluated breast milk samples from the biopsied and non-biopsied breasts.The researchers first isolated potentially cancerous cells, known as epithelial cells, and then isolated DNA to look for signals that regulate tumor suppresser genes.In the next step, the researchers analyzed three genes among the many known to undergo a process called methylation in breast cancer. Methylation in a specific region of a gene can inhibit or suppress the expression of a gene.For one gene, SFRP1, the average methylation was higher in the biopsied breast, the study found.Among the women whose biopsies detected cancer, average methylation of the RASSF1 gene in the biopsied breast was considerably higher compared to the non-biopsied breast.Among the women whose biopsies detected cancer, average methylation of the RASSF1 gene in the biopsied breast was considerably higher compared to the non-biopsied breast."It looks as if we can use the cells from breast milk to assess breast cancer risk," said Dr. Kathleen Arcaro, an associate professor of veterinary and animal sciences at the university.It's too soon, however, to assess the cancer detection rate associated with breast milk cell examination, she said."We can't say at this point for two reasons," she said. "One is, we need long-term follow-up. And the second really important reason is, we need to sample a larger panel of genes."Arcaro is to present her findings later Monday at the annual meeting of the American Association for Cancer Research in Orlando, Florida, according to HealthDay News.

  天津武清区龙济医院男士医院   

WASHINGTON, April 3 (Xinhua) -- In the largest study of its kind, researchers from a consortium led by the University of Pennsylvania School of Medicine, the University of Miami, and the Boston University School of Medicine, identified four new genes linked to Alzheimer's disease. The findings appeared Sunday in the current issue of Nature Genetics.Each gene individually adds to the risk of having this common form of dementia later in life. These new genes offer a portal into what causes Alzheimer's disease and is a major advance in the field.The study, conducted by the Alzheimer's Disease Genetics Consortium, reports genetic analysis of more than 11,000 people with Alzheimer's disease and a nearly equal number of elderly people who have no symptoms of dementia. Three other consortia contributed confirming data from additional people, bringing the total number of people analyzed to over 54,000. The consortium also contributed to the identification of a fifth gene reported by other groups of investigators from the United States, the United Kingdom, France, and other European countries.The study is the result of a large collaborative effort with investigators from 44 universities and research institutions in the United States, led by Gerard Schellenberg at University of Pennsylvania."This is the culmination of years of work on Alzheimer's disease by a large number of scientists, yet it is just the beginning in defining how genes influence memory and intellectual function as we age. We are all tremendously excited by our progress so far, but much remains to be done, both in understanding the genetics and in defining how these genes influence the disease process," Schellenberg said.Until recently, only four genes associated with late-onset Alzheimer's have been confirmed, with the gene for apolipoprotein E-e4, APOE-e4, having the largest effect on risk. The Nature Genetics studies add another four -- MS4A, CD2AP, CD33, and EPHA1 -- and contribute to identifying and confirming two other genes, BIN1 and ABCA7, thereby doubling the number of genes known to contribute Alzheimer's disease.

  天津武清区龙济医院男士医院   

BEIJING, Feb. 27 (Xinhua) -- Chinese Premier Wen Jiabao said during an online chat with netizens here Sunday that the government is striving to ensure that the people live a comfortable life with security and confidence in the period of 2011-2015.China's development blueprint for the coming five years will place high emphasis on the efforts to improve the people's livelihood, Wen said.To enhance the people's living standards is "our work's starting point as well as the final aim," he said.Greater efforts will be made to boost social development and progress, especially in those key sectors and aspects concerning national development and mass interests, the premier said.Wen began his online chat with netizens at 9 a.m. Sunday jointly hosted by the central government website (www.gov.cn) and Xinhua News Agency website (www.news.cn).

  

LOS ANGELES, March 7 (Xinhua) -- U.S. food producer Unilever said on Monday it is recalling two varieties of its Skippy peanut butter because some jars may be contaminated with salmonella.The recall affects jars distributed to retailers in 16 states -- Arkansas, Connecticut, Delaware, Illinois, Iowa, Maine, Minnesota, Missouri, Nebraska, New Hampshire, New Jersey, New York, North Dakota, Pennsylvania, Virginia and Wisconsin, the company said.But the company said no illnesses have been linked to the contaminated Skippy peanut butter.The 16.3-ounce jars are marked with UPC codes 048001006812 and 048001006782 and have Best-If-Used-By Dates of MAY1612LR1, MAY1712LR1, MAY1812LR1, MAY1912LR1, MAY2012LR1 and MAY2112LR1.Unilever advised consumers in a press release to throw away any jars of the recalled peanut butter and to contact the company for a replacement coupon.Salmonella is an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. The most common symptoms are diarrhea, abdominal cramps and fever within eight hours to 72 hours of eating a contaminated product.About 40,000 cases of salmonella are reported each year in the United States, according to the Centers for Disease Control and Prevention.

  

BEIJING, March 22 (Xinhuanet) -- An autopsy began Monday on Berlin zoo's superstar polar bear Knut who died suddenly on Saturday, media reports said.However, it remained unclear when the results from the post-mortem examination of Knut would be published."I cannot give you a timeline. We will inform the public when we know what the exact cause was," AFP quoted spokeswoman Claudia Bienek as saying.Knut died while sunbathing at Berlin zoo in Germany in front of visitors. The four-year-old swivelled around several times before falling backwards into the water in his enclosure.Witnesses said he suffered a series of convulsions and appeared to have had an epileptic fit or a heart attack.Knut was born in 2006 to a female bear who rejected him at birth. He was hand-raised by his keeper at the zoo. Films were made about him and he appeared on the front cover of Vanity Fair magazine and earned the zoo about 7.11 million U.S. dollars.More than 15,000 Knut fans have so far paid tribute to him on Berlin zoo's website. Hundreds more have flocked to the zoo in person to lay flowers at his enclosure.

来源:资阳报

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