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LONDON — U.K. regulators say people who have a “significant history’’ of allergic reactions shouldn’t receive the new Pfizer-BioNTech vaccine while they investigate two adverse reactions that occurred on the first day of the country’s mass vaccination program. Stephen Powis, the national medical director for the U.K.'s National Health Service in England said Wednesday that health authorities were acting on a recommendation from the Medical and Healthcare Products Regulatory Agency. He says the agency has advised, on a precautionary basis, that "people with a significant history of allergic reactions do not receive this vaccination." Powis added that both people are recovering well.Dr. June Raine, head of the U.K.'s Medical and Healthcare Products Regulatory Agency, told Parliament on Wednesday that the reactions were not seen in clinical trials for the drug.“We know from the very extensive clinical trials that this wasn’t a feature,” Raine said, according to the Associated Press. “But If we need to strengthen our advice, now that we have had this experience with the vulnerable populations, the groups who have been selected as a priority, we get that advice to the field immediately.The FDA is currently weighing whether to approve the Pfizer-BioNTech vaccine for emergency use in the United States. 1325

LOS ANGELES (AP) — Officials have vowed to find what sparked the inferno aboard the dive boat Conception that killed 34 people in waters off Southern California, but vital evidence may have gone down with the ship or drifted out to sea.The main piece of evidence, the charred remains of the boat, rests on the sea floor in 60 feet (18 meters) of water. Other items that could provide valuable clues could have been carried away by tides or destroyed in the blaze that burned so hot DNA is needed to identify the dead."All of that will be a very large hurdle to overcome," said George Zeitler, a former Coast Guard inspector who runs his own marine investigation firm. "It will definitely make for a complex investigation."Investigators will want to craft a timeline of the ship's final voyage from the moment it pulled away from a Santa Barbara dock early Saturday morning until dispatchers received the frantic mayday call of the breathless captain overwhelmed by smoke, experts said.RELATED: San Diego woman killed in deadly Conception boat fire off Santa BarbaraThey will look at the ship's layout and whether the bunk room below deck was too cramped and had enough exits, review maintenance records and even study photos and videos from people who have been on the boat to look for valuable evidence.As the investigation into the Labor Day tragedy expands on land and sea, federal and local authorities will look not only at determining what went wrong but also seek lessons that could lead to changes in commercial vessel regulations."Our mission here while we're on scene is to determine how this happened, why it happened and what safety improvements are needed to prevent it from ever happening again," said Jennifer Homendy of the National Transportation Safety Board.The fire, investigated with help from the FBI and Bureau of Alcohol, Tobacco, Firearms and Explosives, is being treated as an accident and there's nothing to suggest anything "nefarious," said Santa Barbara County Sheriff Lt. Erik Raney.The Conception, owned by Truth Aquatics, had been chartered for three days by a commercial dive outfit based in Santa Cruz to explore the rugged Channel Islands, sometimes referred to as the Galapagos of North America, about 20 miles (32 kilometers) south of Santa Barbara.The mayday call came at 3:15 a.m. Monday as passengers would have been sleeping while the boat was anchored just off Santa Cruz Island.While initial details were limited, Santa Barbara County Sheriff Bill Brown said fire above deck blocked the one stairway and an emergency exit hatch where 33 passengers and one crew member were sleeping in their bunks. It's not known if any alarm sounded or what the people below deck may have done to try to escape."If an emergency exit is blocked due to fire and prevents one from escaping, it's a horrific situation," said Hendrik Keijer, an investigator with Robson Forensic who has captained cruise ships and operated cargo boats. "Vessels are mazes."The five survivors were all crew members, including the captain. They apparently jumped from the boat's bow, where the stairway led to the sleeping quarters, and swam to the stern, where they escaped in a dinghy and were taken aboard a nearby boat.Attorney James Mercante, a former merchant marine officer who has defended thousands of maritime casualty cases, said it was unusual that only crew members survived, but that is likely because they were above deck.Mercante said he would want to find out what the crew did upon being alerted to fight the fire and for how long before they abandoned ship."Something was ignited that spread a fire rapidly," Mercante said. "It must have spread awfully quickly if nobody but the crew got out."Even with limited physical evidence, fire investigators should be able to pinpoint where the fire began, though finding the cause will be more difficult, Mercante said.The leading causes of boat fires are, specifically, electrical problems and, generally, stupidity, said Walter Godfrey, who has investigated more than 2,000 boat fires in a career spanning a half-century.By all accounts Godfrey has seen, Truth Aquatics had a good reputation and a clean record of service and was not the type of outfit to employ do-it-yourself electrical wiring."I don't think they'd be cutting those kind of corners," Godfrey said. "I would think just off the top of the head this would have to have been something totally accidental and not something ... you would anticipate."Coast Guard records show fire safety violations on the Conception in 2014 and 2016 were quickly fixed. There were no deficiencies found in February or August 2018 inspections.The same problems that lead to house fires every day can also sink ships: kitchen fires, unextinguished cigarette butts and gas leaks.While experts did not want to speculate on a cause, Godfrey said he would want to know more about the built-in barbecue on board and where gasoline was stored for the dinghy. He said electrical fires are most common because a boat — even when docked — is always moving and wires get chafed and exposed. They can arc and spark or ignite gas vapors.A fire on board can rapidly become a terrifying situation with no help nearby."It's very difficult to fight fires without outside help," Keijer said. "You're really on your own in most instances. It's up to the vessel's crew to fight fires. It's not like one can easily escape a vessel. You walk out of a building if a fire occurs on land. That's not as easy on vessels." 5515

LOS ANGELES (CNS) -- With coronavirus cases on the rise, municipalities in the Los Angeles area Thursday began to crack down on residents who flout the statewide requirement that they wear masks while in public.In West Hollywood, sheriff's Capt. Edward Ramirez issued a statement saying deputies have been working to educate violators about the requirement, but people who refuse could now face fines."Beginning this month, we will continue to utilize education and persuasion and hand out face masks, however, we will begin issuing city of West Hollywood Municipal Code citations to people who refuse to follow the face mask order while in public," he said."The citation, which is administrative and not criminal, is 0 plus a fee of for a total of 0 for the first offense," he said. "Our very least option is to conduct enforcement by issuing a citation, but the risk to community health is too great. To date, we have not issued any citations and we still hope not to."In neighboring Santa Monica, a new health order was announced Thursday in an effort to emphasize the need for face coverings. The order outlines the requirement for people to wear face coverings while in public, and for businesses to enforce the requirement for employees and customers.The revised Santa Monica order sets fines for violators at 0 for a first violation, 0 for a second violation and 0 for a third. For businesses, the fines start at 0, increasing to 0 for a second violation and ,000 for a third."As public health experts have shared widely this week, we are in a dangerous period with dramatic increases in cases and hospitalizations," Interim City Manager Lane Dilg said in a statement. "Face coverings are essential. I encourage everyone to try different styles to find what works for you. But it is a critical time to save lives by wearing face coverings whenever we are outside of our homes and not gathering with people outside of our households."The city of Beverly Hills has long been requiring residents to wear masks. It issued a reminder last week, noting that violators can face fines ranging from 0 for the first offense to 0 for the third and subsequent offenses.Gov. Gavin Newsom -- who made face coverings mandatory across the state on June 18 -- announced a "major public awareness campaign" about the requirement on Thursday. The campaign, backed by .75 million in donations, will feature a series public service announcements in a variety of languages. The announcements will be in the form of broadcast announcements and hundreds of billboards across the state.On Wednesday, Los Angeles Mayor Eric Garcetti said local businesses should refuse service to anyone who refuses to wear a mask."If there's no mask, there should be no service," Garcetti said.The mayor noted that Los Angeles police have not been issuing citations for mask violators, saying the goal is to educate people in hopes of getting voluntary cooperation. 2974

LOS ANGELES -- Fire crews are on scene after a small brush fire broke out in a Los Angeles neighborhood Wednesday night. The fire broke out just before 6:30 p.m. in Pacific Palisades. The fire was originally reported as a half-acre fire. In an alert sent out by the Los Angeles Fire Department, officials said there was no threat to structures. Watch a Facebook live of the brush fire in the player below:  439

LONDON (AP) — Cinema chain Cineworld says it is considering closing all its movie theaters in Britain and the United States, after the postponement of the new James Bond film left a big hole in schedules. Cineworld Group PLC owns 543 Regal cinemas in the U.S. and 128 Cineworld venues in the U.K. and Ireland. It said Sunday it was "considering the temporary closure of our U.K. and U.S. cinemas, but a final decision has not yet been reached." The statement came after the Sunday Times reported that Cineworld's U.K. theaters will shut in the coming weeks. The release of James Bond thriller "No Time to Die" has been delayed from November until April 2021 because of the effect of the coronavirus pandemic. 716