天津市龙济医院医院男性泌尿外科(天津武清龙济泌尿外科医院治早泄) (今日更新中)

Today is the final day of keynote presentations for E3 2019, the largest gaming expo of the year. Perhaps the most anticipated announcements came from Nintendo, which always closes the show.The biggest Nintendo news of the day: 240

Three people are dead and four are missing after a plane crash in a remote northern Labrador lake in Canada.Jean Tremblay, chief executive of the regional airline Air Saguenay, told CBC News that a de Havilland DHC-2 Beaver float plane went down in Mistastin Lake.On board was a pilot for the airline, four passengers and two fishing guides.The plane was heading from a fishing lodge to a remote camp on the lake when it was reported overdue Monday night, according to CBC.The pilot and two others were found dead at the wreckage site, Tremblay told the outlet.The fate of the other four people on the plane is unclear. 631

Three people were shot and a pedestrian was hit by a vehicle during a chaotic night outside the main gates of the Minnesota State Fair.Monday was the final day for this year's state fair, which is located between the cities of Minneapolis and St. Paul.First, a 19-year-old woman who had been struck by a passing vehicle was found by Saint Paul police late Monday night.Witnesses said there had been a fight in the area just before the woman somehow ended up in the road and hit, according to a police statement. The driver of the vehicle initially stopped but left the scene after bystanders began kicking and hitting his vehicle. He drove a short distance away, pulled over and called 911.He is cooperating with investigators, who report no signs of impairment. The woman was taken to a local hospital and listed in critical condition.Gunshot heardSoon after that, gunfire was heard near where the officers were rerouting traffic around the crash scene. Police found one man about a block away with a gunshot wound. He was taken to the hospital with non-life threatening injuries. Two other people with gunshot wounds later turned up at separate hospitals."There's a lot of people in that area," Steve Linders, public information officers for the St. Paul Police Deparment, told 1292

Three US service members and one contractor were killed by an improvised explosive device near Bagram Air Base in Afghanistan on Monday, according to the US military. Three other US service members were wounded.A statement from the military said the wounded service members have been evacuated and are receiving medical care.The Taliban claimed credit for the attack, which targeted a US military convoy near one of America's largest military facilities in Afghanistan.Seven US service members have been killed in Afghanistan this year.The US has about 14,000 troops in Afghanistan, where they primarily advise Afghan forces battling the Taliban and the local ISIS affiliate.While US officials have said that peace talks with the Taliban have made progress, they have yet to finalize any agreements and intense fighting between the government and the insurgency continues.The US envoy to the peace talks, Ambassador Zalmay Khalilzad, left Afghanistan on Sunday following meetings with Afghan president Ashraf Ghani. 1027

The University of Missouri-Kansas City has filed a lawsuit against a former professor, alleging that he stole and sold his graduate student's research for .5 million.The suit, filed this week, says Ashim Mitra swiped a "groundbreaking" drug formulation from the student and stands to gain as much as million more in royalties.Mitra, who has resigned from the university, denied the allegations to CNN.Also named in the lawsuit are Mitra's wife, who worked in her husband's lab, and two pharmaceutical companies that used the invention.The university alleges Mitra worked in secret with the companies to develop the patent, which outlines an innovative way of delivering drugs to the eye using nanotechnologyThe pharmaceutical product has recently received FDA approval, the university said. It's a treatment for dry eye, an ailment common to the elderly.The university's contentionIn a statement to CNN, the university said:"Mitra stole UMKC-owned inventions, sold them to industry, assisted those companies in patenting and commercializing them, denied credit to a deserving student and reaped a personal financial windfall -- all the while concealing his efforts and denying his involvement."The lawsuit seeks to designate the student, Kishore Cholkar, as the rightful inventor to the patent based on his research from 2010.The university policy is that it owns the rights to discoveries made by staff and students while they are working at the university. When commercial rewards are reaped, the inventor is entitled to one-third of the profits and the school keeps the remaining two-thirds, the school said.The professor's reactionReached by phone Thursday, the professor denied the allegations and told CNN that Cholkar doesn't deserve credit for the patent."Everyone is trying to jump in and get a piece of the pie," he said.He said he conceived of the formulation with the drug companies through his private consultancy business, adding that "the student arrived after the patent was signed."Cholkar's work involved a part of the eye not affected by the drug, Mitra said.He added that he's consulting with his lawyers on how best to tackle the lawsuit.Cholkar, the student, now works at a California-based pharmaceutical company. CNN has reached out to Cholkar for comment. 2298

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