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SAN DIEGO (KGTV) -- It's a problem on the rise in communities across San Diego; drivers racing down side streets to avoid rush hour traffic. When Doug Doyen saw speeding on his street, he tried to stop it. "It was almost like the Indy 500 I couldn't believe the speed, the amount of traffic and speed up and down this street," said Doyen.He put up his own signs to get drivers to slow down. "Hold the sign out, wave at them, people would be like, 'what the? Oh okay."' said Doyen. "And they'd look at me like, 'who is this guy?'" But the speeding is still a problem. He thinks GPS apps are directing drivers to his side street to avoid freeway traffic. "I couldn't believe the traffic and the speeds I was seeing out here," he said. Neighbors joined San Diego Police to form a Pace Car Program. The citizen-based campaign adds more signs and traffic patrols in the neighborhood. 937
SAN DIEGO (KGTV) — It’s one of the few drugs shown to help fight the novel coronavirus, and a large federal study on remdesivir just entered a new phase.Previous research sponsored by the National Institute for Allergy and Infectious Disease showed remdesivir shortened recovery time in hospitalized COVID-19 patients on average from 15 days to 11 days.Now scientists and doctors are racing to find the perfect cocktail against COVD-19 by blending remdesivir with other drugs.California-based Gilead Sciences originally developed the drug to fight Ebola, but remdesivir was never approved. Gilead Sciences has offices in Oceanside.The drug works by interrupting the virus’ ability to replicate.“Remdesivir acts by shutting down virus production,” said Dr. Peter Chin-Hong, an infectious disease expert at University of California San Francisco. “It just forces the virus to stop making virus children.”Dr. Chin-Hong is studying remdesivir as part of the NIAID research.The problem is that stopping the virus from replicating isn’t enough for some severely ill patients. They suffer from a second problem: massive inflammation from the immune system’s war with the virus.That’s why scientists are trying a cocktail approach.“You have the virus to take care of, but you also have the body's response to the virus, which is inflammation, that you also have to take care of,” said Dr. Chin-Hong.Researchers started testing the first drug cocktail in May, using an arthritis drug called baricitinib that tames inflammation.But as the data on that part of the study gets crunched, researchers began testing the second cocktail this month, a combination of remdesivir and interferon beta.“Interferon beta is something we produce naturally to fight viruses,” said Dr. Chin-Hong. He said studies have shown people who don’t produce enough interferon beta struggle to fight off the virus.Researchers selected interferon beta after two small studies showed promising results against the coronavirus.Interferon beta can both reduce inflammation and kill viruses, so doctors are hoping it will be a potent one-two punch with remdesivir.Dr. Chin-Hong said he and other researchers started administering the new cocktail this month.Some patients will receive the cocktail, some will receive a placebo, and some will get remdesivir only. This kind of clinical trial is called an adaptive trial, which the FDA started encouraging in 2004. After each phase, the winning drug or cocktail will be tested against a new challenger.Dr. Chin-Hong said the eventual cocktail may include three or more drugs, similar to HIV medication. 2617
SAN DIEGO (KGTV) — Lego fans will have more to look forward to in 2019, as Legoland California plans new attractions in celebration of its 20th birthday.Among one of the park's 2019 offerings: Free admission for kids 12 and under on their birthday, starting in January."Having a chance to reflect on the last 20 years ahead of next year’s birthday celebration, it’s incredible to think about all we’ve accomplished during that time and the amount of kids we positively impacted through their experiences at the Resort," said park General Manager Peter Ronchetti.RELATED: Southern California theme parks ring in the holiday seasonAmong the new additions for 2019, Legoland said it plans to add new attractions and live shows for visitors to experience.One new addition will be a new attraction inspired by "The Lego Movie." The park will host special "Lego Movie" festivities from Feb. 16 - 17 and 23 - 24 around the park ahead of the attraction's opening.The park's resort is also getting a special zone geared toward toddlers modeled after Duplo. The play town will add an express train in the park and kids will be able to ride, slide, and hide in the interactive area.Also being added is a "Lego 4D-Officer in Pursuit" film that will play at the park's theater and new live character shows at the Miniland Stage.It's not exactly clear when the new additions would be opened to guests in 2019. 1458
SAN DIEGO (KGTV) - Mesa Biotech, based in San Diego, has received FDA approval for its rapid COVID-19 tests that can produce results in about half-an-hour.“Our first kits are going out today to some of the health systems, county health departments, to validate the performance against the existing testing,” said Laura Dullanty, a marketing manager at Mesa Biotech. She said it will still take a few weeks before they will be able to deploy them widely to the health care providers who have requested the tests. RELATED: Will you qualify for a ,200 COVID-19 stimulus check?One of the issues has been purely logistical.“In a typical manufacturing line there are a lot of people really close together. Even that's been a challenge to plan that,” said Dullanty. “We’re staggering shifts, taking time in between, cleaning the area well.” Right now, most tests are performed on-site then sent to a lab for processing. It can take several days or longer before a patient knows the results. RELATED: Dyson designs ventilator in 10 days, plans to make 15,000 of them to combat pandemicThe Mesa Biotech rapid test is based on the same PCR technology, but can be performed and processed at the point of contact, such as a hospital, urgent care clinic or a cruise ship infirmary. “We’re estimating having 5,000 - 10,000 a week,” said Dullanty on their production estimates. “Our discussion now that we are authorized is how do we scale that up?” The first batch should be shipped to providers in the next few weeks but it’s up to the health care systems to decide how and when to use them. RELATED: Company working to get FDA approval for fast COVID-19 test“There are some critical patients that maybe need the answer sooner. They are going to screen them in the ER. If it's a negative, they can release them and free up the hospital bed a day sooner,” Dullanty explained. 1871
SAN DIEGO (KGTV) — Inside or outside San Diego Comic-Con, there's plenty to see and do. But one thing attendees always flock to is the exclusives.The great part about the cool toys and collectibles at Comic-Con every year is that you can snag them even without a badge.Inside the convention, there are tons of exclusives fans can wait in line for or vie for a lottery ticket to get simply the chance to purchase something big. But other booths will have plenty of t-shirts, figurines, comic books, and more within budget to check out.SAN DIEGO COMIC-CON: What to know | Off-site activations | Parking | HeadlinesOutside, pop-up shops throughout downtown San Diego will have special installations featuring Comic-Con exclusive gear featuring fan-favorite characters new and old.Here's a handful of awesome swag fans can grab for or less at Comic-Con this year:Inside the conventionMarvel (Booth #2329): Snag some convention exclusive t-shirts priced between - featuring your favorite Marvel heroes, a special Iron Man arc reactor lanyard for , or pin sets starting at .Hasbro (Booth #3329): This iconic The Incredible Hulk 6″ action figure sports the character's classic comic look, featuring a crushed pipe accessory too, for .Mondo (Booth #435): If you love commemorative posters, Mondo has a new set of SDCC exclusive artwork, including Snoopy/Apollo posters for , a Batman: Hush poster for , and a couple of Marvel posters for .Mattel (Booth #2945): Oooh yeeeah. Mattel is selling a “Macho Man” Randy Savage action figure in the style of the wrestlers Slim Jim commercial for . It even comes in a Slim Jim box.Entertainment Earth (Booth #2343): Take a trip to a tropical galaxy far, far away with these convention exclusive Star Wars tiki mugs. Choose from 20 oz. tiki mugs featuring Bossok or Admiral Ackbar for each or a Lando/Nien Nunb 2-pack for .Outside the conventionFYE Pop-up Shop (Horton Plaza): The FYE Pop-up Shop returns with more Comic-Con-exclusive merchandise including specially created cereals for "Child's Play" () and "Kiss" (), a special "Stranger Things" cassette featuring music from the series (), or various t-shirts under .Super7’s “Revenge of the Boodega” shop (701 8th Ave., San Diego): Celebrate Universal Studios Monsters with a special SDCC monsters beach towel for , "monster vision" glasses for , actions figures for , or monster masks for .Arts-Rec (2161 Logan Ave., Barrio Logan): Just a short distance from the convention center, legendary Artist Stan Sakai and Arts-Rec are selling Comic-Con exclusive skateboard decks () and t-shirts () celebrating the 35th anniversary of Usagi Yojimb.Hello Kitty Cafe Truck (Petco Park Interactive Zone): Hello Kitty fans will be treated with exclusive macaron sets featuring Hello Kitty, My Melody, Chococat, Keroppi, & Tuxedo Sam for , confetti popcorn, t-shirts for kids and adults, headbands, canvas totes, exclusive thermal bottles, and more.Comic Pop Up Market + Art Show (WorldBeat Cultural Center, Balboa Park): Check out a free art show filled with handmade goods, artisans, vegan food vendors, Kombucha on tap , face painting and more. While in Balboa Park, check out The Batman Experience at the new Comic-Con Museum too. 3288