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PHOENIX (AP) — Joe Arpaio has been narrowly defeated in his bid to win back the sheriff’s post in metro Phoenix that he held for 24 years before being voted out in 2016. Arpaio on Friday lost the Republican primary to his former top aide, Jerry Sheridan. Sheridan will face the Democrat who previously defeated Arpaio, Paul Penzone, in the November general election. Arpaio also ran an unsuccessful U.S. Senate campaign in 2018, not long after President Donald Trump pardoned his criminal conviction for disobeying a judge’s order. Arpaio is known for launching immigration crackdowns and enacting tough jail policies like jailing inmates in tents. 656

Pfizer announced Friday that it would submit a request to the FDA Friday for its COVID-19 vaccine to be granted Emergency Use Authorization.Earlier this week, Pfizer said that a final analysis of trial results showed the vaccine is 95% effective.“Our work to deliver a safe and effective vaccine has never been more urgent, as we continue to see an alarming rise in the number of cases of COVID-19 globally. Filing in the U.S. represents a critical milestone in our journey to deliver a COVID-19 vaccine to the world and we now have a more complete picture of both the efficacy and safety profile of our vaccine, giving us confidence in its potential,” Dr. Albert Bourla, Pfizer Chairman and CEO, said in a press release.Pfizer's two-shot vaccine has already been in mass production for months, and thousands of doses will be ready for delivery if and when the FDA grants authorization. Pfizer says that is on track to produce 50 million doses of the vaccine by the end of 2020 and plans to produce 1.3 billion doses of the vaccine in 2021.According to "Operation Warp Speed," the federal government's plan for distributing the vaccine, upon authorization, the drug will initially be rationed for high-risk populations and health care workers. Dr. Anthony Fauci, the nation's top infectious disease expert, says he believes a vaccine won't be widely available until April.On Wednesday, Pfizer announced that a final analysis of its vaccine candidate showed that of 40,000 participants who participated in the trial, 170 people had contracted the virus. Of those 170 people, 162 received only a placebo injection — meaning just eight out of the 20,000 people who actually received the vaccine contracted the virus.The company added Wednesday that there have been no safety concerns with the vaccine. In a randomized survey of 8,000 participants, only 2% reported suffering severe fatigue, and only 4% reported suffering severe headaches. Those who say they suffered side effects only experienced them briefly after vaccination.Pfizer's announcement comes as COVID-19 cases are spiking around the world. In the U.S. alone, about 2.5 million people have contracted the virus in the month of November alone. Hospitalizations linked to COVID-19 are at an all-time high, and deaths have begun to tick up in recent weeks. 2322

PARADISE, Calif. (AP) — Authorities searching through the blackened aftermath of California's deadliest wildfire have released the names of about 100 people who are missing, including many in their 80s and 90s, and dozens more could still be unaccounted for.As the names were made public, additional crews joined the search, and the statewide death toll climbed Wednesday to at least 51, with 48 dead in Northern California and three fatalities in Southern California."We want to be able to cover as much ground as quickly as we possibly can," Butte County Sheriff Kory Honea said. "This is a very difficult task."Nearly a week after the blazes began, California Gov. Jerry Brown and Interior Secretary Ryan Zinke toured the area.RELATED: Third person found dead in Woolsey?FireBrown said he spoke Wednesday with President Donald Trump and that the president pledged "the full resources of the federal government.""The natural world is the power, and we create a lot of comfort and we create a lot of security," Brown said. "But at the end of the day, we are physical beings in a biological world."Zinke said many factors contributed to the blazes. He urged people not to "point fingers" and focus on moving forward.A sheriff's department spokeswoman, Megan McMann, acknowledged that the list of the missing was incomplete. She said detectives were concerned about being overwhelmed with calls from relatives if the entire list were released."We can't release them all at once," McMann said. "So they are releasing the names in batches." She said the list would be updated.Authorities have not updated the total number of missing since Sunday, when 228 people were unaccounted for.Meanwhile, friends and relatives of the missing grew increasingly desperate. A message board at a shelter was filled with photos of the missing and pleas for any information."I hope you are okay," read one hand-written note on the board filled with sheets of notebook paper. Another had a picture of a missing man: "If seen, please have him call."Some of the missing are not on the list, said Sol Bechtold, who is searching for his 75-year-old mother, Joanne Caddy, whose house burned down along with the rest of her neighborhood in Magalia, just north of Paradise, the town of 27,000 that was consumed by flames last week.Bechtold said he spoke with the sheriff's office Wednesday morning, and they confirmed they have an active missing person's case on Caddy. But Caddy, a widow who lived alone and did not drive, was not on the list."The list they published is missing a lot of names," Bechtold said. Community members have compiled their own list.Greg Gibson was one of the people searching the message board Tuesday, hoping to find information about his neighbors. They've been reported missing, but he does not know if they tried to escape or hesitated a few minutes too long before fleeing Paradise, where about 7,700 homes were destroyed."It happened so fast. It would have been such an easy decision to stay, but it was the wrong choice," Gibson said from the Neighborhood Church in Chico, California, which was serving as a shelter for some of the more than 1,000 evacuees.Inside the church, evacuee Harold Taylor chatted with newfound friends. The 72-year-old Vietnam veteran, who walks with a cane, said he received a call Thursday morning to evacuate immediately. He saw the flames leaping up behind his house, left with the clothes on his back and barely made it out alive.Along the way, he tried to convince his neighbor to get in his car and evacuate with him, but the neighbor declined. He doesn't know what happened to his friend."We didn't have 10 minutes to get out of there," he said. "It was already in flames downtown, all the local restaurants and stuff," he said.The search for the dead was drawing on portable devices that can identify someone's genetic material in a couple of hours, rather than days or weeks.Before the Paradise tragedy, the deadliest single fire on record in California was a 1933 blaze in Griffith Park in Los Angeles that killed 29.The cause of the fires remained under investigation, but they broke out around the time and place that two utilities reported equipment trouble. Gov.-elect Gavin Newsom, who takes office in January, sidestepped questions about what action should be taken against utilities if their power lines are found to be responsible.People who lost homes in the Northern California blaze sued Pacific Gas & Electric Co. on Tuesday, accusing the utility of negligence and blaming it for the fire. An email to PG&E was not immediately returned.Linda Rawlings was on a daylong fishing trip with her husband and 85-year-old father when the fire broke out.Her next-door neighbors opened the back gate so her three dogs could escape before they fled the flames, and the dogs were picked up several days later waiting patiently in the charred remains of their home, she said.After days of uncertainty, Rawlings learned Tuesday that her "Smurf blue" home in Magalia burned to the ground.She sat looking shell-shocked on the curb outside a hotel in Corning."Before, you always have hope," she said. "You don't want to give up. But now we know."___Contributing to this report were Associated Press writers Sudhin Thanawala, Janie Har, Jocelyn Gecker and Olga R. Rodriguez in San Francisco. 5345

OVERLAND PARK, Kan. — A United States Postal Service worker discovered a massive snake Friday while delivering the mail in Overland Park, Kansas.It's unclear when the red tail boa constrictor slithered onto the home in the Pinehurst neighborhood."The biggest snake I've ever seen! Looked like it had just had lunch," Holly Gibson, a neighbor said.The snake's size didn't make it easy for the responding animal control officer."It was too big for her to get and put in a box by herself so called in her boss, the police came," Gibson said. 556

PARKLAND, Fla. (KGTV AND CNN) - School shooting suspect Nikolas Cruz plans to plead guilty, according to Howard Finkelstein, Broward County public defender.17 people were shot and killed at Marjory Stoneman Douglas High School in Parkland Wednesday.Cruz, 19, was arrested nearby after the shooting. He confessed to police, according to the Associated Press. He faces 17 counts of premeditated murder.“It’s to avoid the unnecessary arduous long painful traumatic reenactment of something that is so horrific the families and the community should not have to relive," Finkelstein told CNN. "Everybody knows who committed the crime and that the only question is does he live or does he die."RELATED: What we know about Nikolas?CruzHe continued: "It seems it’s in no one’s interest to do the same old legal dance we have seen play out across the country way too many times.This is an opportunity to put the criminal case behind and help the victims’ families begin to try and pick up pieces of their lives for our community to heal and to figure out how we stop these things from ever happening again,” Finkelstein said 1133

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