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SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648
SAN DIEGO (KGTV) - Members of a newly formed Guardian Angels chapter in Pacific Beach went on patrol for the first time Saturday night.Members of the Sacramento Chapter traveled to San Diego to train the new volunteers. Administrator Sarah Bonesteel joined after a neighborhood crime walk, saying "crime is getting out of control, we've lost our parks, and our library and things like that."RELATED: Guardian Angels look to start street patrols in Pacific BeachThe Guardian Angels are a national crime prevention nonprofit organization that started in New York in 1979. The group said it created chapters in over 130 cities in 13 countries.While the group has several programs to prevent crime, the most visible are its street patrols. The Pacific Beach Chapter hopes to provide a safe environment after the bars close.Guardian Angels patrol in groups of at least two while wearing red berets and uniforms, and say the patrols are meant to serve as a visual deterrent and aim to avoid violent confrontations.Angels on patrols are unarmed but trained in self-defense to protect themselves in case a situation becomes physical. They hope they do not have to use their training.The organization conducts background checks on new members to ensure everyone's safety. 1270

SAN DIEGO (KGTV) - Kion Gould still lives at the La Jolla Crossroads Apartments, where one year ago on his birthday a gunman opened fire, hitting him and six others.He survived, but his friend Monique Clark died. He spent a month in the hospital recovering from three gunshot wounds. When he got out, he went back to his gym routine and says now he’s physically back in shape. But “mentally, there is anguish,” he says.His life has become a study in what happens to mass shooting victims who survive.The shooting plays out in his head often, reliving the day in vivid detail.“It seemed like it happened yesterday,” he says.It was April 30, 2017. Gould says things were winding down at the pool and they were about to head to dinner in Pacific Beach.He was heading toward the pool gate when he noticed a man lying by himself on a lounge chair.He remembers telling him, “It’s my birthday, come have a good time. We’ve got food, we’ve got drinks, we’ve got girls. That’s exactly what I said.”The man, now identified as Peter Selis, did not respond with words. Instead, he pulled out a .45 caliber handgun.“I didn’t think it was a real threat until he basically raised the gun toward my head,” said Gould.He remembered thinking part of him wanted to jump on top of the man and rip the gun away. But something held him back as he tried to rationalize the situation. Why would someone have a gun there?“What stopped me was the thought that he was a special needs person that had a toy,” he remembered. “Then I thought he was an undercover cop.”But within seconds it became clear it was not a fake and he intended to use it. Reflexively, Gould raised his arms over his face.Selis’ first shot hit his left arm.“I remember seeing blood dripping down my face so I thought I was shot in the head.”He turned to run and was hit twice in the back.He was able to make it out of the gate and up a set of stairs where he collapsed overlooking the pool.“I was up above everything and I was witnessing him shooting everyone. Like he’s just there shooting, reloading. Shooting, reloading.”Meantime, Kalli Seely was down on the pool deck. She had her purse strung over her shoulder and was on her way out when the shooting began.“I heard the first gunshot and looked automatically at Kion for some reason,” said Seely.But she couldn’t tell what was going on yet.“Then I felt something hit my arm,” she said. “I thought somebody threw something at me.”It wasn’t until she heard a friend yell “gun!” that she realized what was happening.She had been shot twice. Once in the arm and once in her left breast.“I was like ‘am I going to die?’ because that’s what you think when you get shot in the chest,” she thought.Later she would learn the bullet did not strike any vital organs but she ended up nearly passing out on the lawn outside the pool. Someone picked her up and brought her to a sidewalk on Judicial Drive where they waited for an ambulance.But as police arrived, they began closing off all the roads around the complex, blocking even ambulances from getting through. A few minutes later, Seely says a security guard drove by and took her and two other victims to the area where first responders were waiting.“Within 20 minutes we were in the hospital while the rest of them were scared, bleeding, in the pool area with the guy still shooting,” she said.By the time police killed Selis, seven people had been shot.Gould’s friend Monique Clark later died.“She had always been a happy person,” he said.Clark almost didn’t come. Gould said they had been hanging out several days before when he accidentally closed his car door on her finger, breaking it.“She was just mad at me. She didn’t hate me,” he said. But she was reluctant to come until Gould worked his charm to convince her.“I would gladly give my life for her to be here,” he now says, specifically because of her three children.“I would trade places with her, easily, without a doubt so she could be there for them. She will be forever in my heart.”Gould was eventually taken to am ambulance and remembers being conscious until he was sedated at the hospital.It turned out, the bullet did not make it through his arm into his head. Only a fragment had struck his eyelid.“The doctor was surprised I stopped the .45 with my bone,” said Gould.Doctors credited his strong physique for saving his life. While some of the fingers on his left hand are now numb, he says his body has made a full recovery.That’s only one step in the healing process though, he says.“There’s an aftermath that happens to all of this,” referring not just this shooting, but to victims of all shootings.“People just have developed [a] numbness to ‘oh, there’s a shooting. And another shooting.’ ”Seely agreed, observing mass shootings become widely publicized, then the media and the public move on to the next. The pain of the victims, especially the ones who survive, often gets forgotten she says.“There’s a deep pain that doesn’t go away and it lives with you everyday and it never stops.”Both describe it as a lingering weight.“I try and push it to the back of my head and forget that it’s there, but as soon as things are quiet and I go to mundane, everyday tasks it creeps right back in,” said Seely.Gould says he and another one of the shooting survivors have enrolled in an experimental PTSD treatment study at UCSD. But he’s skeptical it will help.Even though the shooter is dead, Gould says his hatred towards Selis can be all-consuming.“He created, this tragic, unforgiving, relentless thing that’s continuing to influence our lives. And you can never have that back.” 5625
SAN DIEGO (KGTV) - Keeping kids active, while also letting them follow their passion, is a top priority for a lot of parents.But often it comes at a cost. A new study from CompareCards.com shows that 46% of parents spend more than ,000 a year on activities for their kids, and 27% spend more than ,000. "As much as we love our kids as parents, and as much as we want them to pursue their dreams, life is expensive in 2019," says Matt Schulz, an Industry Analyst with CompareCards.com. "Parents are spending an awful lot of money to keep their kids in these activities."According to the study, 62% of parents admit they go into debt to pay for it all. 64% of parents say the costs cause them added stress.RELATED: Making It In San Diego: Community colleges offer free tuition to San Diego students"It's important to support your kids and teach them to follow their dreams," says Schulz. "But you also have to be able to do so without ruining your own dreams."One San Diego parent thinks she has a way to help. Jessica Mendez is trying to launch an online marketplace where parents can trade used sports equipment to help defray the costs."Every season, kids grow," says Mendez. "Every few months you have to purchase new cleats, a new bat to grow with them."Mendez has four boys that have been involved in all kinds of sports. As they've grown, old equipment has piled up in her garage. She thinks other parents have the same stockpiles of gear going to waste.RELATED: Making it in San Diego: State offers money to help boost college savings accountsMendez is hoping to let parents trade equipment with each other."We're hoping to start small and grow in the future with a website," she says. Mendez thinks she can have the site up in about a year. She's asking other parents with similar stockpiles of gear to contact her at jessicasdhomes@gmail.com.Meanwhile, CompareCards says parents can get creative to cut costs when it comes to activities. Some of their ideas include:- Having kids use YouTube or other online videos for tutorials instead of private lessons- Putting their kids in cheaper, non-elite and non-travel leagues (like YMCA or local recreation center leagues)- Having age-appropriate kids do extra work and pitch in to pay for registration- Saying "No" when too many activities start to pile up- Combining travel for club sports with the family vacationRELATED: Making it in San Diego: Millions available for local studentsShawanee White, a mother of three, says she's sold some of her daughter's old equipment and toys online to help pay for registration. She also asked other family members to chip in some money instead of buying toys for birthday or holiday gifts.White says her family spends -6,000 a year on registration, travel and all the other costs associated with extracurricular activities. But it's worth it."I want them to be well rounded and exposed to many opportunities," she says, adding that the activities keep her kids away from doing anything that may get them into trouble.The study also found that nearly 80% of parents believe their child's activities could one day lead to income, whether in the form of a scholarship, job or side-hustle.Schulz says it's also essential to involve your children in discussions about how their activities factor into the budget."It makes sense to be open and honest with your kids about the cost of these things," he says. 3411
SAN DIEGO (KGTV) - Interstate 15 Express Lane signs are being changed from white to green, with other improvements, at a cost of .5 million, the San Diego County Association of Governments said Thursday.A research effort determined that the existing signs could be difficult for drivers to read, and that information about toll rates and permission to use the lanes was unclear, according to SANDAG."There's quite a bit of confusion on the motorists part, trying to understand, can I actually get in there as a carpool or not?" said Ray Traynor, SANDAG's director of operations. "Having a system that's clear to the end users is vitally important so that the lanes operate effectively."A spokesman for Caltrans says research showed a green sign with white text was more difficult to read, with the amount of information on the sign. The I-15 Express Lanes stretch for 20 miles between SR-78 in Escondido and SR-163 in Kearny Mesa. There are more than 16 access points where drivers can move in or out of the lanes.WHAT WILL CHANGEThe upgraded signs were designed to address the concerns from I-15 commuters.Improvements include: 1153
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