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WASHINGTON, Nov. 24 (Xinhua) -- An inexpensive drug that treats Type 2 diabetes has been shown to prevent a number of natural and man-made chemicals from stimulating the growth of breast cancer cells, according to a newly published study by a Michigan State University researcher. The research, led by pediatrics professor James Trosko and colleagues from South Korea's Seoul National University, provides biological evidence for previously reported epidemiological surveys that long-term use of the drug metformin for Type 2 diabetes reduces the risk of diabetes-associated cancers, such as breast cancers.The research appeared online this week in PLoS One.For the study, Trosko and colleagues focused on the concept that cancers originate from adult human stem cells and that there are many natural and man-made chemicals that enhance the growth of breast cancer cells. Using culture dishes, they grew miniature human breast tumors, or mammospheres, that activated a certain stem cell gene. Then the mammospheres were exposed to natural estrogen -- a known growth factor and potential breast tumor promoter -- and man-made chemicals that are known to promote tumors or disrupt the endocrine system.The team found that estrogen and the chemicals caused the mammospheres to increase in numbers and size. However, with metformin added, the numbers and size of the mammospheres were dramatically reduced. While each of the chemicals enhanced growth by different means, metformin seemed to be able to inhibit their stimulated growth in all cases."While future studies are needed to understand the exact mechanism by which metformin works to reduce the growth of breast cancers, this study reveals the need to determine if the drug might be used as a preventive drug and for individuals who have no indication of any existing cancers," Trosko said.

BEIJING, Jan. 9 (Xinhua) -- The United States Treasury Secretary Timothy Geithner will discuss economic ties and exchange views with Chinese officials on the global economic situation during his trip to China, Foreign Ministry spokesman Liu Weimin said on Monday.Liu said at a regular press briefing that Geithner will visit China from Jan. 10 to 11 as the U.S. President's special representative. Premier Wen Jiabao, Vice President Xi Jinping, Vice Premier Li Keqiang and Vice Premier Wang Qishan will meet with him during the visit.Liu said China and the U.S. have agreed to build a partnership of cooperation based on mutual respect and mutual benefit."The global economic and financial situation is facing severe challenges. Further strengthening China-U.S. economic and trade cooperation will be helpful in meeting these challenges," Liu said."China has proposed further promoting the two countries' economic and trade cooperation and hopes the U.S. will work with China toward this end," Liu said.
BEIJING, Jan. 6 (Xinhua) -- Surveillance data on the size and frequency of earthquakes in Antarctica collected by China's Great Wall Station show that the continent is not earthquake-free, a Chinese seismic expert said Thursday."China's newly-built seismic observatory in Great Wall Station has documented a hundred-odd earthquakes occurring in the region over the past year," said Chang Lijun, a member of China's 28th Antarctic expedition team.The discovery challenges the prevailing notion that the Antarctic has no earthquakes, as many earthquakes have gone undetected due to lack of seismological observation in the region.However, thanks to technological advances, scientists have discovered that the continent is still subject to some minor tremors.Chang, also an associate researcher at China Earthquake Administration's Geophysics Institute, said last year's earthquakes ranged in magnitude from 0.5 to 4, scales which are usually undetectable to common people.The tectonic movements of Antarctica, which sits on two plates that pulled away from each other in the northern Ross Sea between 28 and 40 million years ago, but later converged, fascinate geologists worldwide.At the end of 2010, Chinese scientists set up a new broadband seismic observatory in Great Wall Station, greatly increasing China's ability to measure tremors and tectonic movements on the continent.
来源:资阳报