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The Trump Administration pushed through a million contract to study whether the active ingredient in Pepcid is an effective treatment for Covid-19. That contract is now under scrutiny after a government whistleblower accused a senior administration official of rushing the deal through without the scientific oversight necessary for such a large federal award. The Food and Drug Administration gave the clinical trial speedy approval even as a top agency official worried that daily injections of high doses of famotidine for already sick patients pushed the levels of what was considered safe “to the limits,” internal government emails show. And the doctors who initially pushed the Pepcid idea are locked in a battle for credit and sniping over allegations of scientific misconduct.The origins of the interest in famotidine are under dispute, but there were reports out of China that patients who took the drug survived the virus, while patients who took other heartburn medications were not surviving. Initial observational studies in the U.S. were promising, however scientists urged more research was needed. Meantime, the trial itself that was part of the million contract is on pause due to a shortage of hospitalized COVID-19 patients in New York, delaying it indefinitely. A vaccine or effective treatment could be available before the study is complete. 1380

The U.S. Census Bureau says only a tiny percentage of records are affected by data irregularities that are putting in jeopardy a year-end deadline for turning in numbers used for divvying up congressional seats. However, released internal documents show the "high complexity" problems could push the release to February 2021. The Census Bureau told a congressional committee Thursday that the anomalies are being resolved as quickly as possible. House Democrats however say documents they obtained from Census sources, despite Trump administration stonewalling, show hundreds of thousands of records are affected.Fixing the irregularities could mean missing a Dec. 31 deadline for the Census Bureau to turn reapportionment numbers in to Congress. The internal Census documents shared by House Democrats show the data issues, which include several "high complexity" problems, could delay the once-a-decade report until February. Although the documents do not specify the extent of the larger issues, they do say incorrect handling of the issues could skew the count smaller or larger in some areas. They also say the Census Bureau estimates they need an additional 20 days for data processing. The bureau says the timeline remains in flux.The Census Bureau issued a statement asserting that "these kinds of anomalies and issues are expected and are similar to the Census Bureau's experience in prior decennial censuses." The Census Bureau Director acknowledged the issues in mid-November, more details and the delayed timeline are coming out now. The timeline is getting attention because it may or may not be after President Donald Trump leaves office on January 20. Trump has expressed interest in excluding unauthorized immigrants from the Census count. There have been challenges in court and questions about whether this could legally be done, and also whether it physically can be done by coming up with a reliable number to exclude. Three lower courts have blocked the directive from Trump saying it violates federal law that says the census should could the "whole number of persons" in each state. The Supreme Court just this week heard arguments in the case. They have not issued their ruling yet. 2215

The Supreme Court has ruled that LGBTQ employees are protected under federal employment discrimination laws in a landmark decision.The court ruled 6-3 in favor of granting protection from discrimination to LGBT workers, with conservatives Chief Justice John Roberts and Justice Neil Gorsuch siding with the majority.According to the ruling, Title VII of the Civil Rights Act of 1964 that prohibits discriminating against workers on the basis of sex also applies to gay, lesbian, transgender people.“An employer who fires an individual for being homosexual or transgender fires that person for traits or actions it would not have questioned in members of a different sex,” Justice Neil Gorsuch wrote in the opinion. “Sex plays a necessary and undisguisable role in the decision, exactly what Title VII forbids.”Justice Samuel Alito wrote the dissenting argument.The case Bostock vs. Clayton County, Georgia entered around a Georgia man, Gerald Bostock, who claimed he was fired for "unbecoming" conduct from his job with Clayton, County, Georgia, after he began participating in a gay softball league.The decision also ruled in favor of Aimee Stephens in the case R.G. & G.R. Harris Funeral Homes Inc. v. Equal Employment Opportunity Commission. Stephens, a trans woman, was fired from her job at a Michigan funeral home when she expressed her desire to live full time as a woman. 1391

The US House of Representatives passed a federal "right-to-try" bill Wednesday night, leaving many Americans wondering what the move could mean for their health and that of their loved ones.The bill, backed by President Donald Trump, would give terminally ill patients the right to seek drug treatments that remain in clinical trials and have passed phase one of the Food and Drug Administration's approval process, but they have not been fully approved by the FDA.The bill passed the House 267 to 149, after failing to pass last week. Now the legislation needs approval from the Senate.Right-to-try laws exist in 38 states -- Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maine, Maryland, Michigan, Minnesota, Mississippi, Missouri, Montana, Nevada, New Hampshire, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, West Virginia, Washington and Wyoming -- but this federal bill would introduce legislation across state lines.The central question, however, remains: Would a federal right-to-try bill help or hurt some of the country's most fragile patients? Here's what you need to know, according to experts on both sides of the legislation. 1320

The swarm happening now south of the Salton Sea, near Westmoreland is over 30 km south of the end of the San Andreas. It is in the Brawley seismic zone, a common source of swarms. So far largest is M4.4. Too far from the San Andreas to change the probability of a quake on it.— Dr. Lucy Jones (@DrLucyJones) September 30, 2020 340

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