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Mail deliveries could be delayed by a day or more under cost-cutting efforts being imposed by the new postmaster general. The plan eliminates overtime for hundreds of thousands of postal workers and says employees must adopt a "different mindset” to ensure the Postal Service survives the coronavirus pandemic. "The initial step in our pivot is targeted on transportation and the soaring costs we incur, due to late trips and extra trips, which costs the organization somewhere around 0 million in added expenses," the 2-page notice states. The plan calls for limiting overtime, late or extra trips are "no longer authorized or accepted.""One aspect of these changes that may be difficult for employees is that.- temporarily - we may see mail left behind or mail on the workroom floor or docks (in P&DCs), which is not typical."Postal Service leaders say in a document obtained by The Associated Press that if postal distribution centers are running late, “they will keep the mail for the next day."The document is dated July 10, and says many of the changes will happen immediately. The changes come a month after a major donor to President Donald Trump, Louis DeJoy, took over the sprawling mail service. 1221

Maryland-based vaccine developer, Novavax, has received .6 billion from the federal government to complete late-stage clinical development; set up large-scale manufacturing; and deliver 100 million doses of NVX?CoV2373, its COVID-19 vaccine candidate, as early as late 2020.This is the largest vaccine deal to date with the Trump administration as part of their Operation Warp Speed, which is focused on making a COVID-19 vaccine and treatments available as quickly as possible.Novavax has not brought any of their developed vaccines to market. According to information on their website, they have developed several vaccines for infectious diseases, however they are all in various stages of development or clinical trials. These include vaccines for the seasonal flu and RSV. Other vaccines created by Novavax are not actively being developed or studied at this time, including ones for Ebola, MERS, and SARS.According to a statement from Novavax, the agreement with the federal government includes the company demonstrating being able to rapidly get manufacturing and large-scale production of the vaccine going once approved. Novavax hopes to conduct their late-stage clinical study with 30,000 subjects in fall 2020.An early-stage clinical study took place in Australia in May on 130 participants. Study results are expected at the end of July.“Today’s .6 billion investment supports the Novavax candidate, depending on success in clinical trials, all the way through to manufacturing 100 million doses for the American people,” said U.S. Health and Human Services Secretary Alex Azar.Regeneron Pharmaceuticals has also received 0 million through Operation Warp Speed on Tuesday, to make and supply its COVID-19 vaccine candidate, REGN-COV2. Their vaccine is currently in phase 2 and phase 3 clinical studies for the treatment and prevention of COVID-19.Regeneron has several vaccines on the market currently, including Dupixent, used to treat allergic diseases such as eczema, asthma and nasal polyps which result in chronic sinusitis, and Praluent, used to treat high cholesterol. 2101

Maryland-based vaccine developer, Novavax, has received .6 billion from the federal government to complete late-stage clinical development; set up large-scale manufacturing; and deliver 100 million doses of NVX?CoV2373, its COVID-19 vaccine candidate, as early as late 2020.This is the largest vaccine deal to date with the Trump administration as part of their Operation Warp Speed, which is focused on making a COVID-19 vaccine and treatments available as quickly as possible.Novavax has not brought any of their developed vaccines to market. According to information on their website, they have developed several vaccines for infectious diseases, however they are all in various stages of development or clinical trials. These include vaccines for the seasonal flu and RSV. Other vaccines created by Novavax are not actively being developed or studied at this time, including ones for Ebola, MERS, and SARS.According to a statement from Novavax, the agreement with the federal government includes the company demonstrating being able to rapidly get manufacturing and large-scale production of the vaccine going once approved. Novavax hopes to conduct their late-stage clinical study with 30,000 subjects in fall 2020.An early-stage clinical study took place in Australia in May on 130 participants. Study results are expected at the end of July.“Today’s .6 billion investment supports the Novavax candidate, depending on success in clinical trials, all the way through to manufacturing 100 million doses for the American people,” said U.S. Health and Human Services Secretary Alex Azar.Regeneron Pharmaceuticals has also received 0 million through Operation Warp Speed on Tuesday, to make and supply its COVID-19 vaccine candidate, REGN-COV2. Their vaccine is currently in phase 2 and phase 3 clinical studies for the treatment and prevention of COVID-19.Regeneron has several vaccines on the market currently, including Dupixent, used to treat allergic diseases such as eczema, asthma and nasal polyps which result in chronic sinusitis, and Praluent, used to treat high cholesterol. 2101

Louisville Mayor Greg Fischer announced that a citywide curfew will be extended through the weekend as unrest in the city reignited on Wednesday.The demonstrations were sparked by a grand jury announcement that charges would not be filed against the two officers who shot and killed Breonna Taylor during a March raid.The curfew will continue from 9 p.m. to 6:30 a.m. every day through Monday. The curfew does not apply to people commuting to work, house of worship for services or seeking medical attention for themselves or others.The city has also closed some of the city’s downtown government facilities through Monday morning.On Wednesday, 127 arrests were tied to demonstrations in the city. Amid the unrest, two Louisville Metro Police officers were wounded by a gunman. A suspect, Larynzo Johnson, was arrested on Wednesday. Johnson is accused of shooting the two officers who were patrolling demonstrations in the city. 936

MIAMI (AP) — A 2-year-old girl is recovering after falling from a fourth-floor window of a Miami apartment. Miami Fire Rescue Capt. Ignatius Carroll told WPLG that a palm tree under the window helped slow the speed of the child's fall early Monday. She landed in some bushes. She was being cuddled by her uncle and was crying when rescue crews arrived at the scene. The girl was then taken to a hospital for treatment. Miami Police Cmdr. Freddie Cruz told the TV station that detectives were trying to determine what led to the fall and whether the girl's parents bear any responsibility.No additional details were immediately available. 645

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