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The coronavirus pandemic means people across the globe are practicing social distancing and staying at home whenever possible. To help pass the time, Hallmark is playing a Christmas movie marathon this weekend — because St. Patrick's Day is over and it's clearly time to get in the Christmas spirit? Die-hard 321

The entire US auto industry would shutdown within a week if President Donald Trump goes through with his pledge to close the US-Mexican border, according to a leading expert on the industry.That's because every automaker operating an auto plant in the United States depends on parts imported from Mexico, said Kristin Dziczek, the vice president of industry, labor and economics at the Center for Automotive Research.About 37% of all auto parts imported to the United States originate in Mexico. Virtually all car models in America have Mexican parts, she said. Because of that reliance, she said the auto industry would stop producing vehicles relatively quickly."You can't sell cars with missing pieces," she said. "You've got to have them all. I see the whole industry shutdown within a week of a border closing."President Trump is threatening to 862

The 2019 Nobel Prize for Medicine has been jointly awarded to William Kaelin Jr., Sir Peter Ratcliffe and Gregg Semenza for their pioneering research into how human cells respond to changing oxygen levels.Announcing the prize at the Karolinska Institute in Stockholm on Monday, the Nobel committee said that the trio's discoveries have paved the way for "promising new strategies to fight anaemia, cancer and many other diseases."The 2019 medicine laureates, the committee added, have identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen.The importance of oxygen has long been established, the committee explained, but how cells adapt to changes in its levels remained unknown.Randall Johnson, prize committee member, described the trio's work as a "textbook discovery.""This is something basic biology students will be learning about when they study, at aged 12 or 13, or younger, biology and learn the fundamental ways cells work. This is a basic aspect of how a cell works and, from that standpoint alone, it's a very exciting thing."The winnersNew York-born Kaelin established his own research laboratory at the Dana-Farber Cancer Institute in Boston and became a full professor at Harvard Medical School in 2002.Semenza, also born in New York, became a full-time professor at Johns Hopkins University in 1999 and since 2003 has been the Director of the Vascular Research Program at the Johns Hopkins Institute for Cell Engineering.Ratcliffe, who was born in Lancashire, England, studied medicine at Cambridge University and established an independent research group at Oxford University, becoming a full professor in 1996. 1694

The company that made billions selling the prescription painkiller OxyContin has filed for bankruptcy days after reaching a tentative settlement with many of the state and local governments suing it over the toll of opioids.The filing late Sunday night in White Plains, New York, was anticipated before and after the tentative deal, which could be worth up to billion over time, was struck.But legal battles still lie ahead for Purdue. About half the states have not signed onto the proposal. Several of them plan to object to the settlement in bankruptcy court and to continue litigation in other courts against members of the Sackler family, which owns the company.The bankruptcy means that Purdue will likely be removed from the first federal opioid trial, scheduled to start in Cleveland on Oct. 21. 819

Text messages received overnight on Wednesday caused confusion, misunderstandings and even alarm for some recipients.The messages appear to have originally been sent on February 14, Valentine's Day, but were received more than eight months later with Wednesday's time stamp.The issue occurred across all four major carriers in the United States and affected both Apple and Android devices.People shared their experiences about receiving delayed messages on social media and Reddit. Some said they received text messages from ex-boyfriends and ex-girlfriends that led to awkward conversations. Others said the messages came from relatives or friends who had since passed away. One person complained to Sprint's Twitter account that her phone had 757

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