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SAN DIEGO (CNS) - The Collaborative Clinical Trials Unit at UC San Diego has been selected to lead and administer an international seven-year, million grant for HIV/AIDS clinical trials.The National Institutes of Health selected UCSD, along with other American, South African and Indian research hospitals, as part of its seven-year HIV/AIDS funding renewal. Every seven years, NIH competitively renews its funding of the HIV clinical trials networks operating in the United States and internationally.During the current application process, the UC San Diego AntiViral Research Center, University of Colorado Hospital, Houston AIDS Research Team and Durban International clinical research sites were chosen to work collaboratively on research priorities for the NIH/National Institute of Allergy and Infectious Diseases HIV/AIDS Adult Therapeutics Clinical Trials Network.The Chennai Antiviral Research and Treatment Center, University of Southern California and University of Miami clinical research sites were also chosen to join UCSD to serve as qualified reserve or protocol-specific sites as needed for future clinical trials."UC San Diego has helped shape HIV/AIDS research and treatment through innovative research since the inception of the adult and pediatric therapeutic clinical trials networks in 1986," said principal investigator Dr. Constance A. Benson, director of UCSD's Antiviral Research Center."Together, the seven clinical research sites selected by the NIH for the HIV therapeutic clinical trials network bring together a wealth of scientific expertise, experience and the high quality performance required to conduct complex clinical trials," she said.Abouty 38 million people are living with HIV/AIDS globally, with 1.7 million acquiring HIV in 2019 alone. In the United States, 1.2 million people are living with the virus.The UCSD-led clinical trials unit serves several regions in the United States burdened by chronic and new HIV infections as well as global regions impacted by both HIV and tuberculosis.The unit will investigate therapeutic strategies aimed at a cure for HIV, including evaluating viral persistence, researching antibody approaches to treatment and prevention and investigating treatment of inflammation and its impact on HIV comorbidities.In addition, investigators will study new drugs including long-acting drug formulations for HIV treatment and prevention, HIV-related coinfections and comorbidities -- including metabolic and end organ complications and a hepatitis B cure, as well as the treatment and prevention of tuberculosis, including TB preventive vaccines, in persons with mono- and HIV-coinfection."We are honored to lead a talented pool of investigators in a common goal of advancing research that clinically benefits people living with HIV," Benson said. 2830

SAN DIEGO (CNS) - The aircraft carrier USS Nimitz and elements of the Nimitz Carrier Strike Group deployed from San Diego Monday in support of global maritime security operations, Navy officials announced.Prior to departing, the strike group completed a composite training unit exercise called COMPTUEX, which is designed to fully integrate units of a carrier strike group while testing its ability as a whole to carry out sustained combat operations from the sea.Ships, squadrons and staffs have been tested across every core warfare area within their mission sets through a variety of simulated and live events, including air warfare, strait transits, and responses to surface and subsurface contacts and electronic attacks, according to U.S. Third Fleet public affairs."The carrier strike group team is trained and ready," said Rear Adm. Jim Kirk, commander of the strike group. "The men and women of Carrier Strike Group 11 have demonstrated exceptional tactical and technical expertise, teamwork and toughness. We are honored to answer the call and operate forward."In addition to conducting maritime security operations whenever and wherever called upon, strike-group units will participate in cooperative engagements, multilateral exercises and unit-level training designed to improve capability and capacity among Navy units and partner nations in the regions they may operate in.All personnel assigned to the group completed a minimum 14-day quarantine ashore and were tested for COVID-19 prior to getting underway with their respective units. Sailors assigned to Nimitz completed a 27-day fast cruise aboard the ship which also included their testing period for the virus.In addition to the Nimitz, deploying units include Carrier Air Wing 17, Ticonderoga-class guided-missile cruiser USS Princeton and Destroyer Squadron 9, which includes Arleigh Burke-class guided-missile destroyers USS Sterett and USS Ralph Johnson.Sterett departed Naval Base San Diego on Thursday, Princeton steamed out on Saturday and Ralph Johnson is scheduled to leave Tuesday, according to the Navy. 2094

SAN DIEGO (CNS) - Testimony wrapped up Friday in the trial of a North Carolina man accused of raping and murdering a 79-year-old woman in her Normal Heights home more than three decades ago.Kevin Thomas Ford, 63, is charged with murder and a special- circumstance allegation of murder during a rape in connection with the May 20, 1987, death of Grace Hayden.Ford is accused of strangling the victim. Last year, investigators with the District Attorney's Office's identified Ford as a suspect through DNA evidence, prosecutors say, as well as a single fingerprint he allegedly left on Hayden's stovetop.RELATED: April trial date set for man accused in 1987 rape, murder of San Diego womanTrial testimony indicated that Ford's fingerprint did not yield results on a San Diego County database, but when submitted to a national database, a match was found in connection with Ford's 2015 arrest in North Carolina for making criminal threats.He was subsequently arrested in the summer of 2018.His murder trial began earlier this week at the downtown San Diego courthouse. Closing arguments are slated to be delivered Tuesday morning. He remains held in custody without bail. 1176

SAN DIEGO (CNS) - San Diego's Bumble Bee Foods filed for Chapter 11 bankruptcy protection Thursday, facing criminal fines and civil litigation after the company pleaded guilty to a price-fixing scheme with rival seafood companies Starkist Co. and Chicken of the Sea Inc.Bumble Bee filed for bankruptcy protection in Wilmington, Delaware, listing up to billion in both assets and liabilities, according to a Los Angeles Times report. FCF Fishery Co. is expected to acquire the company's assets for more than 0 million through a competitive bidding process. Bumble Bee is currently owned by Lion Capital, an English private equity firm.The company pleaded guilty to the price-fixing scheme in 2017, admitting that the three companies conspired to raise the price of canned and packaged tuna in the U.S. from 2011 to 2013. The U.S. Department of Justice levied an .5-million fine against Bumble Bee and later slashed it to million due to Bumble Bee's outstanding debts.RELATED: StarKist admits fixing tuna prices, faces 0-million fine"The division, along with our law enforcement colleagues, will continue to hold these companies and their executives accountable for conduct that targeted a staple in American households," Andrew Finch, then the Justice Department Antitrust Division's acting assistant attorney general, said when Bumble Bee pleaded guilty in May 2017.At that time, Bumble Bee argued the original fine could drive it to bankruptcy. The company's court documents show that it still owes some million of the fine and faces multiple class-action lawsuits and litigation from companies that distribute and sell its products.Bumble Bee was founded in 1899 by the Columbia River Packers Association, which officially introduced the Bumble Bee brand of canned seafood in 1910. The company expanded to San Diego in 1977 when it purchased the Harbor Industry cannery.After 12 years in Kearny Mesa, the company moved its headquarters back to downtown San Diego in 2014, where it currently resides adjacent to Petco Park. 2052

SAN DIEGO (CNS) - Regal Cinemas might be closing all 543 of its theaters in the United States as early as this week due to continued revenue losses from the coronavirus pandemic.``We can confirm we are considering the temporary closure of our U.K. and US cinemas, but a final decision has not yet been reached. Once a decision has been made we will update all staff and customers as soon as we can,'' the theater chain's parent company Cineworld tweeted on Sunday.A report in Variety the previous day, which cited an unidentified source, said the company would be closing its theatres in the United States and the United Kingdom as early as this week.Regal is the second-largest theater chain in the United States after AMC.The chain has eight locations in San Diego County. Indoor movie theaters are currently permitted at reduced capacity in the county, and with other protocols in place to prevent the spread of COVID-19.Variety's report came one day after it was announced that the release of the latest James Bond film, ``No Time to Die,'' would be postponed until April 2021. Large chains such as Regal count on blockbusters like the Bond films to sustain operations. 1181