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WASHINGTON, April 25 (Xinhua) -- Study by scientists at the Rockefeller University shows that anti-inflammatory drugs reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors (SSRIs), taken for depression and obsessive-compulsive disorder and anxiety disorders.This discovery, published online Monday in the Proceedings of the National Academy of Sciences, may explain why so many depressed patients taking SSRIs do not respond to antidepressant treatment and suggests that this lack of effectiveness may be preventable.The study may be especially significant in the case of Alzheimer's disease. Such patients commonly suffer from depression and unless this can be treated successfully, the course of the illness is likely to be more severe. Depression in the elderly is also a risk factor for developing Alzheimer's Disease and researchers have suggested that treating depression in the elderly might reduce the risk of developing the disease.In the recent study, investigators treated mice with antidepressants in the presence or absence of anti-inflammatory drugs. They then examined how the mice behaved in tasks that are sensitive to antidepressant treatment. They found that the mice's behavioral responses to antidepressants were inhibited by anti- inflammatory/analgesic treatments.They then confirmed these effects in a human population. Depressed individuals who reported anti-inflammatory drug use were much less likely to have their symptoms relieved by an antidepressant than depressed patients who reported no anti- inflammatory drug use. The effect was rather dramatic since, in the absence of any anti-inflammatory or analgesic use, 54 percent of patients responded to the antidepressant, whereas success rates dropped to approximately 40 percent for those who reported using anti-inflammatory agents."Many elderly individuals suffering from depression also have arthritic or related diseases and as a consequence are taking both antidepressant and anti-inflammatory medications. Our results suggest that physicians should carefully balance the advantages and disadvantages of continuing anti-inflammatory therapy in patients being treated with antidepressant medications," leader author Paul Greengard said.

CHENGDU, Jan. 30 (Xinhua) -- Over the crowds of holiday shoppers in China's big stores this Spring Festival lingers an atmosphere of suspicion.With charges of price deception hanging over the big chains of Carrefour and Wal-Mart and local authorities moving to levy fines, many Chinese -- normally averse to be pinching pennies during the Lunar New Year -- are checking their receipts at the tills.The New Year, which falls on Feb. 3 this year, is normally a time of largesse and excess -- all the more reason why many shoppers feel so betrayed.Customers can be seen recording label prices in notebooks or calculating their final bill on their mobile phones as they walk the aisles.At outlets of Carrefour and Wal-Mart in cities such as Beijing, Shanghai and Chengdu, the check out queues have grown as customers doublecheck prices at the tills."I would never have imagined global firms would do this intentionally and I have to be cautious," said a woman surnamed Wang, after shopping at a foreign-owned supermarket in Chengdu, southwest China's Sichuan Province.With three bulging shopping bags, Wang stood next to the check out to calculate the final bill: "We buy a lot for the New Year celebrations, so I have to be more careful."The official weeklong Spring Festival holiday, which starts Wednesday, is China's closest equivalent to the West's Christmas shopping season, with generous gifts of food, tobacco, liquor and other presents for family and friends.According to the Ministry of Commerce, China's retail sales hit 340 billion yuan (49.8 billion U.S. dollars) during the Spring Festival holiday week last year."The deceptive pricing practices of the two foreign-funded supermarket giants were a total scandal," said Wang. "I have to be careful with the prices and the labels.""Cheating by the supermarkets is the same as stealing. I might have suffered losses as I don't normally check receipts," said a Chengdu man surnamed Li.Wal-Mart (China) Investment Co., Ltd. offered a "sincere apology" to affected customers on Thursday. The company has been cooperating with investigations into the cheating. It has also launched inspections of stores nationwide.Chen Bo, spokesperson for Carrefour China, said Sunday that Carrefour sincerely apologized to Chinese customers for inconvenience and losses caused by pricing irregularities.Carrefour would refund customers five times the difference between the price charged and that on the label. The refund policy would be implemented at Carrefour's 182 outlets in China.The issue is continuing to smoulder on the Internet, with websites asking people to write in with "your experiences of price cheating by the Carrefour."A survey by Sohu, one of China's major web portals, had resulted late Sunday in 8,451 of 9,507 respondents saying they "would not go to Carrefour as it is blacklisted for price cheating.""Carrefour will further strengthen price label management and improve service quality to gain the support and confidence of Chinese customers," said Chen Bo.Carrefour had drawn up short and long-term measures to solve the price label issue, including price inspections, improving and upgrading the price label system, and comprehensive staff training."We will have our special control group conduct frequent and wide-ranging internal price inspections," Chen said.The National Development and Reform Commission (NDRC), China's top economic planner and price regulator, said Wednesday that some Carrefour and Wal-Mart stores in China were involved in deceptive pricing practices.The NDRC ordered local pricing authorities to urge stores to correct their wrongdoing, and pay fines five times the illegal income. It also urged authorities to step up price checks ahead of the Spring Festival.

TAIPEI, Jan. 29 (Xinhua) -- Nora Sun, granddaughter of Sun Yat-sen, the forerunner of China's revolution to end feudalism, died Saturday afternoon in a Taipei hospital, about one month after being injured in a car accident.Sun, 72, was severely injured in a car crash while on her way to an airport near Taipei on Jan. 1. She was in stable condition after several operations, but her condition abruptly deteriorated Saturday afternoon, according to hospital officials, without giving additional details.Sun, who spent most of her time in Shanghai, came to Taipei to attend the Flora Expo. While returning to Taoyuan International Airport near Taipei the black sedan Sun was riding in crashed head-on into an oncoming vehicle, described as a red car. Sun had planned to return to Hong Kong that day.Sun's car had been driven by a friend. The driver of the red car, who was believed to be speeding, according to police, died on the spot. Sun, her friend, and an injured passenger in the red car were immediately transported to a hospital. .Sun is the youngest daughter of Sun Fo, son of Sun Yat-sen, the leader of the 1911 Revolution that ended imperial rule in China.

PYONGYANG, Feb. 14 (Xinhua) -- Kim Yong Nam, president of the Presidium of the Supreme People's Assembly of the Democratic People's Republic of Korea (DPRK), met Chinese Minister of Public Security Meng Jianzhu here on Monday.Kim said it was the consistent stand of the Worker's Party of Korea (WPK) and the government and the firm will of the people to develop the traditional DPRK-China friendship generation after generation.The DPRK is sincerely happy to see the great achievement China has made and wish that the Chinese people make even more progress, Kim said.Meng, also a State Councilor, said the traditional friendship between the two neighboring countries has strengthened through the ages. He expressed his expectations of inheriting the friendship, deepening communications and cooperation in various areas and promoting the China-DPRK friendship.Ri Yong Ho, Presidium of Political Bureau of Central Committee of WPK and chief of the Korean People's Army General Staff, also met Meng on the same day.Ju Sang Song, a member of the Political Bureau of Central Committee of the WPK and Minister of People's Security, met Meng on Sunday. The two achieved consensus on making more efforts to develop cooperation and communications on public security to make active contributions to the traditional China-DPRK friendship. An agreement on cooperation between the the two security ministries was signed after the meeting.Meng arrived at Pyongyang on Sunday at the invitation of Ju Sang Song.

BEIJING, Feb. 10 (Xinhua) -- First snow fell in Beijing Wednesday night and continued into Thursday morning. It was the latest first snow for the city in 60 years.Beijing has had no precipitation for 108 consecutive days this winter.Local meteorologists said from 8:00 Wednesday to 6:00 Thursday, precipitation in Beijing averaged 1 mm."Now there is snow at last. I love the taste of snow." "The world in pure white! It's the most beautiful landscape in winter." Beijing residents who stayed late in the night and happened to see the first flakes of snow in the city left their postings on microblogs.However, meteorologists said the first snow won't last long and it will end on Thursday noon. In midnight, the city will have a cloudy weather, and Friday will be a sunny day."As the precipitation is small, it will have limited effect on easing drought," Song Jisong, the municipal meteorological bureau's chief weather forecaster said.Sun said that the capital city's record-long winter drought occurred in the winter of 1970/71, when there was no precipitation for 114 days. This winter drought was the second longest in 60 years.Meteorologists said the current snowfall will reduce risks of fire.The snow also affected the city's traffic. Local traffic control authorities estimated that there were more than 40 highways on which vehicles ran at a speed lower than 20 km per hour in the rush hour Thursday morning.The authorities said an emergency headquarters had been set up for the snow weather. Expressways connecting Beijing with Chengde, Tianjin and Tibet will likely have some sections closed for the time being.A spokesperson with the Beijing Capital International Airport Co., Ltd. said that by 6:00 a.m. Thursday, runways at the airport had operated normally, and take-offs and landings had been normal, with no flights delayed.The airport has also launched an emergency scheme. At last 64 ice removal vehicles had been arranged to ensure the normal operaton of flights.Wednesday also saw snowfall and sleet in Gansu, Shaanxi, Shanxi, Henan and Anhui provinces and rainfall in the Yellow River and Huaihe River valleys, southwestern regions and the middle-and-lower reaches of the Yangtze River valley. And snow and rainfall will continue in the those areas Thursday.