北京长期高尿酸降不下来(山东痛风能喝功能饮料吗) (今日更新中)

SAN DIEGO (KGTV) — The back-to-back announcements of promising clinical trial results from Pfizer and Moderna may usher in a new era for vaccine technology.Both companies have candidates that rely on a new kind of vaccine strategy: RNA. Preliminary data show both candidates are more than 90 percent effective.On the surface, the vaccine candidates look like any other you’ve taken. They work by training your body to build up defensive weapons against a virus, like antibodies and T-cells.But instead of training your body by introducing a killed virus or a fragment of a virus, the vaccines from Moderna and Pfizer introduce a set of instructions called messenger RNA enclosed in a little blob of fat.“The key concept of RNA is that they’re messages, and they’re meant as short-term messages,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.Crotty said there are 5,000 to 10,000 messages within a cell at any given time.Once administered, the mRNA in the vaccine instructs some of your cells to make the coronavirus’ signature spike protein. The spike protein on the surface of the coronavirus allows it to infiltrate and hijack cells.Even though the spike protein is just one of about 25 genes the virus has, preliminary results from the clinical trials suggest it is enough material to train the immune system without making the recipient sick.Crotty likened the process of training the immune system to spotting a sedan. If the coronavirus is a car, the spike protein might be the door.“There's no way that car door could turn into a whole car, but it's enough of a piece of a car for your immune system to recognize that car if it saw it again,” he said.Scientists started by sequencing the virus’ DNA from a sick patient, then encoding that genetic sequence into an mRNA instruction molecule that can be read by the manufacturing part of cells.From there, Dr. Crotty said it’s a bit like the messenger app Snapchat.The mRNA gets injected into the body, sending temporary instructions to your cells that last for a while, then disappear. mRNA does not genetically modify cells, he stressed.“They’re around as messages for some period of time and then they go away, and the cells get back to their normal job of reading their own messages instead of reading the messages you’re injecting in the vaccine,” he said.The concept has been around since the 1990s, but there are currently no RNA vaccines on the market for any pathogen, so Dr. Crotty said it’s hard to estimate how long their protective effects will last.Some vaccines offer a lifetime of protection, like the measles vaccine. Others offer decades of protection. The flu vaccine only lasts about six months.Dr. Crotty said the length of protection depends on how fast the virus mutates and how long the immune cells survive in the body.But even if the COVID-19 vaccine turns out to need an annual update, he’s optimistic. The best feature of RNA vaccines is that they can be quickly reprogrammed.Both Moderna and Pfizer are still in their Phase 3 trials, but they expect to finish them by December. Together, they estimate they’ll have enough doses for about 35 million people by the end of this year, primarily for healthcare workers and high-risk individuals. 3250

SAN DIEGO (KGTV) -- Tens of thousands of San Diego Gas & Electric customers in San Diego’s East County were without power Tuesday morning as strong Santa Ana winds continue to swirl in the region.As of 1 p.m., 10,982 customers were without service in communities including as Alpine, Campo, Julian, Ramona, and Valley Center. SDG&E said another 35,431 customers in areas including Chula Vista, El Cajon, Poway, and San Marcos could potentially have power turned off.LATEST PINPOINT WEATHER FORECASTCiting the region's Red Flag warning and the power shutoffs, the San Diego County Office of Education said schools in the following districts would be closed on Dec. 8:Alpine UnionValley Center-Pauma UnifiedWarner UnifiedMountain Empire Unified School District: schools will offer asynchronous learning, where students may work independently reading, watching pre-recorded lessons, or doing assignments, projects, or online activities (where power is available)SDG&E will open one resource center each in Descanso, Julian, Potrero, Ramona and Valley Center. Those centers will remain open until 10 p.m. and offer access to water, Wi-Fi, ice, snacks, phone and medical device charging, water trucks for livestock and up-to-date information on outages. All five centers also have a drive-thru option.For an updated list of communities affected by the Public Safety Power Shutoff or to find a resource center, visit sdge.com/public-safety-power-shutoff.Residents brace for high windsOn Monday, in Valley Center’s Hellhole Canyon, wind gusts reached 82 MPH, according to the National Weather Service.Some business owners across San Diego County prepared for the possibility of losing power.“If the café does lose power, we do have a generator at home, so we’d probably prioritize the business over the home,” said Anamaria Kent, who runs Cleveland Café in Alpine with her mother.“We don’t panic; we’ve been through a few power outages,” said Kent. “When we get any sort of notification that the power will go out, we do everything possible that we need with the power.”“Living where we live up here in the mountains, you’re kind of used to this stuff,” said Larry McNamer, who owns Major’s Diner in Pine Valley.McNamer lost power at his Pine Valley home around 5 p.m. Monday. The diner also lost power after just going through a round of shutoffs days ago.“Fortunately for us, we’re closed on Tuesdays and Wednesdays anyway, so this time it works out,” he said.Cal Fire officials continue to remind everyone that fire season is still here in San Diego County. Last week, the Willow Fire, fueled by Santa Ana Winds, destroyed one home in Rancho San Diego and damaged several more.On Dec. 7, three years ago, what started as a small fire just east of Bonsall, quickly grew and spread into the Lilac Fire, burning thousands of across and destroying more than 100 homes.“Is it something that we all have in the back of our minds? Yes. And we do everything and have done everything that we could possibly do to make sure that we’re ready and prepared,” said McNamer. 3075

SAN DIEGO (KGTV) - Students from around San Diego are using a modern medium to learn and inspire.The Cesar Chavez Service Clubs, which has chapters at 22 local schools, has launched the "Chavistas Podcast."Once a month, they interview a local leader, learning that person's story. They hope it can inspire other kids to reach for the stars."We feel that, as a community of Chavistas, that we can get a good message of community out there," say Ariana Gallegos, the club supervisor.Gallegos has a background in radio broadcasting and uses that to help the kids craft their interviews."It's a beautiful experience that I get to bring the students to a setting that sometimes is hard to be at," says Galleos. "But it allows them to see that if I can do it, you can do it."Students in the club say it's been a fun experience. They hope other kids will listen and learn."When it turnes out good, it's really nice, just feeling like you accomplished something good," says Wilson Elementary 7th Grader Mecklin Montgomery. "I like getting other people's information out there, and I want people to hear their story and possibly be inspired by it."To listen to the podcast, click here. 1184

SAN DIEGO (KGTV) -- The first Tuesday of every August, people across the nation recognize National Night Out.The night is designed to strengthen neighborhood spirit and police-community relations and heighten crime and drug prevention awareness.Thousands of people throughout the county are expected to attend this year’s National Night Out.Check out the list below for locations: 388

SAN DIEGO (KGTV) - The family of a man who was hit and killed by an Amtrak train Tuesday night is grieving and hoping he doesn't die in vain.Wentian He, 79, was walking across the train tracks toward the bus stop when he was hit and killed by an Amtrak train, according to his daughter Lilian Zheng. Zheng said her parents were on their way home from shopping.Wednesday, her mother was sobbing, saying she didn't want to live by herself.Zheng said her parents were married 54 years and she saw her dad as a healthy man, young and strong."He really enjoy[ed] learning the streets, the culture, how to behave in this foreign country. He worked really really hard," she said he was part of the Communist Army in China and it took him a while to get 'un-brainwashed'.Her parents emigrated to the U.S. in 2007 and she says they've been enjoying retirement, "They always together go out, they like to go to the senior center, because they can meet new people, they go to the flea market, or small shops so they can find unique stuff."Those trips, now cherished memories.Zheng hopes change can be made at the Washington Street station to protect people like her father. "The two tracks are so close they can cross, there is no [barrier] when Amtrak came, there should be a second gate," suggesting another barrier between the two sets of tracks."I feel life is so fragile, you know he's such a strong father and we've been depending on him," Zheng said tearfully, now they're leaning on each other.Zheng has a sister and niece in China. She hopes to bring her sister to the U.S., so they may fulfill her father's wish to show her the U.S., and bring his remains home to China. 1677

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