济南尿酸含量高济南痛风去哪个科室看,山东痛风所有关节都会疼吗,山东治痛风大概多钱,山东有痛风有治的方法吗,山东痛风结石切除手术,山东青岛痛风研究所,济南痛风初期治疗方法

CORONADO, Calif. (KGTV) — Coronado officials warned beachgoers of two shark sightings on Sunday, almost 10 days following four other sightings.The city posted on Facebook that two white shark sightings occurred off South Beach at 9:10 a.m. and 9:30 a.m. Officials added that a local surfer who reported the second sighting said the shark was possibly longer than 10 feet and seen about 50 yards offshore.Both sightings occurred near Tower 1C at Avenida de las Arenas, and the shark did not show any engaging behavior. Beachgoers were alerted Sunday and encouraged to check with lifeguards before going into the water. Sunday's sightings come nearly 10 days after Coronado said four shark sightings in two and a half hours prompted warnings. 748

Cleveland Browns fans at 10 bars in the northern Ohio city could be treated to free beer when the team wins a game.Bud Light is inside the Browns Victory Fridges, according to ESPN. The 8-foot fridges are in bars that purchased them and are filled with bottles of the beer, which is the official beer of 28 of 32 NFL teams.At the end of the next win by the Cleveland Browns, which haven't won a game since Week 16 in 2016 against the San Diego Chargers, the electromagnet that keeps the refrigerators locked will be turned off through a WiFi connection, ESPN reports.Bud Light is making this happen to reward fans who are loyal to the Cleveland Browns, its VP of marketing told ESPN. 691

Consumers are reportedly not pleased with Walmart as the retail giant faces backlash for selling a T-shirt with the words "All Lives Matter" on it.The shirt is being sold by third-party vendor Old Glory, according to Walmart's website.CNN reported that social media users are criticizing the retailer for allegedly "mocking" the Black Lives Matter movement.The T-shirts are being sold online by Walmart.com and Walmart Canada, according to CNN. 452

COLUMBUS, Ohio -- Republicans in the Ohio House of Representatives began a lame-duck session Thursday by passing a bill that would ban most abortions after the first detection of a fetal heartbeat. That milestone can arrive as early as six weeks into a pregnancy.The Republican-controlled House voted 58-35 Thursday in favor of the legislation, which does not include exceptions for rape or incest.The bill provides “a more consistent and reliable marker for the courts to use” when considering abortion laws’ constitutionality, said Rep. Christina Hagan, a Stark County Republican and the bill’s co-sponsor.The American Civil Liberties Union called the measure “a total abortion ban” and promised to sue if it becomes law. Kasich vetoed a similar bill in December 2016, siding with opponents who contend it is unconstitutional.The bill will advance to the Ohio Senate. 897

Could the no-calorie sweetener you rely on to replace sugar in your diet actually cause weight gain instead of the weight loss you were expecting?The answer may be yes, according to a new study."Artificial sweeteners are not risk-free," said Brian Hoffmann, assistant professor in the Department of Biomedical Engineering at the Medical College of Wisconsin and Marquette University, and a lead author of the study. "They are a very controversial topic when it comes to health and nutrition ... but they're so prevalent in society that I think we owe it to ourselves to try and figure out what's actually going on."Hoffmann presented his new research Sunday at the annual?Experimental Biology meeting in San Diego. Relying on rats and human cell cultures, his team identified a number of pathways linking artificial sweeteners with metabolic changes at the genetic level that could lead to diabetes and obesity. Specifically, the researchers found that three weeks of exposure to aspartame and acesulfame potassium -- two artificial sweeteners frequently combined in products such as Equal -- altered the expression of certain genes responsible for lipid metabolism in the cells of both rats and humans."Aspartame had some significant changes, and one of those was an increase in lipids in the bloodstream and a decrease in a biomolecule that is involved in clearing (lipids) from the bloodstream. And we saw the exact same thing with the acesulfame potassium," Hoffmann said."We then took those particular sweeteners and put them on endothelial cells -- the cells that line the blood vessels and would be exposed to them in the body -- and we detected a marked dysfunction, suggesting why sweeteners and diet soda have been linked to potential cardiovascular problems," he added.What was perhaps most surprising, according to Hoffmann, was that these metabolic changes did not occur in the presence of natural sugars such as glucose and fructose. This suggests that artificial sweeteners could contribute to metabolic disorders such as diabetes and obesity by an entirely different mechanism than natural sugars, he said.Artificial sweeteners appear to contribute to metabolic disorders by altering the activity of certain genes responsible for the breakdown of macromolecules such as fats and proteins, Hoffmann said. This is different from normal sugars, which contribute to cardiovascular disease through insulin resistance and by damaging the cells lining the body's blood vessels."People are generally consuming non-nutritive sweeteners believing they are a 'healthy choice,' but this may not be true," said research scientist Meghan Azad of the University of Manitoba in Winnipeg, who was not involved in the new study."This is especially important given the widespread and increasing consumption of artificial sweeteners in the general population and the increasing use of artificial sweeteners in our food supply," said Azad, who has authored a paper that reviewed a number of studies on the potential downside of artificial sweeteners on weight and health.According to Azad, over 40% of adult Americans consume no-cal sweeteners on a daily basis, and studies that measure the sweeteners in blood and urine show that many people who report not using artificial sweeteners are unknowingly consuming them.It's the latest assault in the ongoing debate over artificial sweeteners and their impact on health -- a debate that began when one of our most popular foods, sugar, turned sour in terms of health. 3527