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WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.

CANBERRA, April 14 (Xinhua) -- The Australian federal government could struggle to get its carbon tax through parliament, as key independent Member of Parliament (MP) Tony Windsor on Thursday warned the plan may never become a reality.Windsor, who is one of the independents Prime Minister Julia Gillard will rely on to get her carbon tax pass the Parliament, said while climate action will benefit the bush, he will not "vote for something that does nothing"."There is no carbon tax, there may not be a carbon tax," he told ABC News on Thursday morning."The prime minister doesn't have the numbers, as I understand it at the moment."I have a vote, others do as well, so you can never guarantee something before it gets through a minority parliament."Windsor said people in his rural New South Wales electorate were concerned about the lack of detail around the proposed carbon tax.Gillard played down his comments, saying that Windsor, who sits on the multi-party climate change committee, had been "perfectly consistent" in his approach to the carbon price debate."He does believe climate change is real ... that pricing carbon is the best way, an important way, of tackling climate change," Gillard told ABC Radio on Thursday."(But) he's going to look at the (legislative) package and wait to the end and then judge (it)."Gillard added that the Labor government remains determined to introduce a carbon tax from mid-2012 followed by an emissions trading scheme.

SAN FRANCISCO, May 6 (Xinhua) -- Bud Tribble, Apple's vice president of software technology, will testify at the Congressional hearings on mobile privacy next week, according to the witness list released on Friday.Tribble will represent Apple at the hearings of the U.S. Senate Judiciary Subcommittee on Privacy, Technology and the Law. The hearings, entitled "Protecting Mobile Privacy: Your Smartphones, Tablets, Cell Phones and Your Privacy," is scheduled to take place next Tuesday in the wake of an iPhone location database controversy.Tribble is one of the industry's top experts in software design and object-oriented programming, known for helping to design the Mac OS and user interface. He is considered as the right-hand man of Apple CEO Steve Jobs and has been with Jobs since they developed the original Macintosh. When Jobs was forced to resign from Apple in 1985, Tribble followed Jobs and co-founded another computer company NeXT Computer. He rejoined Apple and Jobs in 2002.At the upcoming Congressional hearing, Tribble will be joined by Alan Davidson, Google's director of public policy for the Americas.Apple has been under heavy fire after it was alleged last month that its iphones and other smart phones had been collecting customers' location information. In the wake of the controversy, U. S. senator Al Franken, chairman of the Senate Judiciary Subcommittee on Privacy, Technology and the Law, scheduled the mobile privacy hearing and asked representatives from Apple and Google to testify.Apple has denied the alleged practice and released software updates to make iPhone store less location information to quell public concerns over privacy.

WASHINGTON, April 4 (Xinhua) -- The U.S. National Aeronautics and Space Administration (NASA) announced on Monday that following discussions among the International Space Station partners on Sunday, it is delaying the launch of space shuttle Endeavour's STS- 134 mission to April 29 from April 19.The new launch time is set for 3:47 p.m. EDT (1947 GMT) on Friday, April 29."The delay removes a scheduling conflict with a Russian Progress supply vehicle scheduled to launch April 27 and arrive at the station April 29," NASA said in a statement.NASA managers will hold a Flight Readiness Review on Tuesday, April 19, to assess the team's readiness to support launch. An official launch date will be selected at the conclusion of the meeting.Endeavour will deliver to the space station a 2-billion-dollar, multinational particle detector known as the Alpha Magnetic Spectrometer.

SAN FRANCISCO, April 7 (Xinhua) -- Google's Android will become the most popular smartphone operating system worldwide and will account for 49 percent of the market by 2012, IT research and advisory firm Gartner said Thursday.According to Gartner's projections, worldwide smartphone sales will reach 468 million units in 2011, a 57.7 percent increase from 2010.The company predicts that Apple's iOS will remain the second biggest platform worldwide through 2014 although its share will decrease slightly after 2011, on the assumption that "Apple will be interested in maintaining margins rather than pursuing market share by changing its pricing strategy."Microsoft's Windows, driven by its partnership with Nokia, is expected to move into the mid-tier by the end of 2012 and become the third largest in the worldwide ranking by 2013.Some analysts raised doubts on Gartner's forecasts, saying that its assumption on Apple's price strategy contradicts statements by Apple's chief operating officer Tim Cook and the cooperation between Nokia and Microsoft will not have that much of an impact on smartphone market share by 2012.