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A vintage plane crashed in the Swiss Alps on Saturday, killing all 20 people on board, police said.The mid-century plane, a Junkers JU-52, crashed in the Piz Segnas mountain range, near the Austrian border.All 17 passengers and three crew members died in the crash, which happened around 5 p.m. local time. They were aged between 42 and 84. 348

A new study suggests misguided antibodies created as a response when someone is infected with the coronavirus could be the cause behind both more severe COVID-19 symptoms and those who report having symptoms for months after initially recovering.Researchers at Yale University found that COVID-19 patients they studied had high levels of antibodies that had turned on them; these wayward antibodies blocked antiviral defenses, wiped out helpful immune cells and attacked the body in several areas including the brain, blood vessels, liver and gastrointestinal tract.“Covid-19 patients make autoantibodies that actually interfere with immune responses against the virus,” Aaron Ring, an immunobiologist at Yale and senior author on the study, told The Guardian.Autoantibodies are antibodies that attack the body’s own proteins by mistake and disrupt their normal functions.“We certainly believe that these autoantibodies are harmful to patients with Covid-19,” said Ring. He added that the harmful effects of these autoantibodies could continue well after the initial infection has been overcome. He said antibodies can last for a long time, and if they are misguided in their attacks, the effects of their attacks on the body could also last a while.The study, which has yet to be peer reviewed and formally published, looked at antibodies from 194 COVID-19 patients and hospital workers with a range of symptoms and severity of symptoms.Other conditions, like lupus, multiple sclerosis and rheumatoid arthritis, are also made worse by the immune system malfunctioning and attacking the body. 1600

A request from children is changing the future of LEGO kits. The company announced they will be phasing out their single-use plastic bags used to separate parts of their kits beginning next year.“We have received many letters from children about the environment asking us to remove single-use plastic packaging. We have been exploring alternatives for some time and the passion and ideas from children inspired us to begin to make the change,” stated CEO Niels Christiansen in a company release.The toymaker has set a goal of making all of their packaging sustainable by the end of 2025. Beginning in 2021, they will look at using recyclable paper bags in their kits.Testing has already taken place, and LEGO says kids liked the paper bags because they were environmentally friendly and easy to open.Other LEGO products will be getting an environmentally friendly makeover in the future, too. The company said it is testing blocks made from sugar cane and other sustainable materials. 992

A student was taken into custody Friday after a shooting at a Noblesville, Indiana, middle school left three people injured, officials said.Noblesville police Chief Kevin Jowitt told reporters that a teacher and a student were taken to hospitals with injuries from the shooting at Noblesville West Middle School. But hospital officials said at least three people, including one adult, were being treated. One student had an ankle fracture.Jowitt said the shooting in the city of 60,000, about 25 miles northeast of Indianapolis, was reported shortly after 9 a.m.A student asked for permission to leave the classroom and "he returned armed with two handguns," Jowitt said at an afternoon news conference.The situation was quickly resolved, and the student was arrested in or near the classroom, police public information officer Lt. Bruce Barnes said.Jowitt said a secondary threat was received at Noblesville High School."We have multiple officers and a command post established at Noblesville High School and are diligently ensuring the safety of students and staff there," he said. "We have not received any information that this has been anything other than a communicated threat."Barnes said police are seeking several search warrants in their investigation. Police don't know the motive or where the guns came from, he said.Authorities did not release the name of the suspect or the names and conditions of the injured people. However, the teacher was identified as Jason Seaman, 29, according to his aunt, Brenda Hubly-Sushka.Gov. Eric J. Holcomb, who was returning from a trip to Europe, said in a statement that he was monitoring the situation and that about 100 Indiana State Police officers were made available to work with local authorities."Our thoughts are with all those affected by this horrible situation," his statement said.Vice President Mike Pence tweeted, "Karen and I are praying for the victims of the terrible shooting in Indiana. To everyone in the Noblesville community -- you are on our hearts and in our prayers. Thanks for the swift response by Hoosier law enforcement and first responders."The middle school was on lockdown part of the morning, said Jackie Chatteron, a receptionist for the school district. Aerial news video showed rows of students being evacuated and escorted to school buses. Students were taken to Noblesville High for parents to pick up, state police said.June 1 is the last day of classes, according to the school's website.The shooting comes a week after 10 people were killed at a school in Santa Fe, Texas.There have been 23 school shootings where someone was hurt or killed so far this year -- an average of more than one shooting a week. 2704

A string of five arrests in one week is highlighting a new trend in the drug smuggling business. Teens are strapping Fentanyl to their stomachs and back and trying to walk it across the border.Since March 27th, US Border Patrol agents have made five such arrests of teenagers at the San Ysidro port of entry."It's something that the US Attorney's office is not going to sit idly by and watch the cartels manipulate these children," says Deptuty US Attorney Mark Conover.Overall, Fentanyl smuggling is on the rise. Officials say it's up 1250% since 2015. And between 2016 and 2017, the number of Fentanyl seizures at San Diego's border went up from 260 to 952.But it hasn't been until the last few months that agents started seeing teens trying to move the drug."Cartels are using high school students to recruit other high school students," says Conover. "Oftentimes it's underpriveleged students that need a few hundred dollars are are willing to assume the risk of strapping drugs to their body."The arrests show that most of the teens are US Citizens who live in Mexico with their families. They cross the border every morning for school. Many don't know the danger associated with the drug.Fentanyl is extremely potent. The amount that it takes to cause a fatal overdose is smaller than the size of Abraham Lincoln's face on a penny. Agents worry that if the package the teens are smuggling breaks, it could kill them and others around them.Already in 2018, there have been 8 confirmed overdose deaths from Fentanyl in San Diego, with another 12 under suspicion.  In 2017, there were 82. As recently as 2014, when the first Fentanyl seizure was made at the border, there were only 15."This is a binational problem, and it requires a binational solution," says Conover.The US Attorney's office met this week with the Mexican Consular General in San Diego to discuss ways to fight the new trend. They plan PSAs that will air on both sides of the border, and an educational program where they can go into schools and teach kids the legal and physical dangers of becoming a drug mule."We certainly hope the kids that would consider this, once they know the risks, once the know the consequences, once they know there's very little upside for themselves, they'll think twice," says Conover.The US Attorney's office is also working with the DA's office in San Diego on prosecuting offenders. But since the teens are in the juvenile system, oftentimes the punishment is light. For adults, 400 grams of Fentanyl carries a mandatory 10-year sentence. The US Attorney's office is hoping they can target the adults dealing the drug in the US and the Cartels supplying it in Mexico to stop the trend.They've already prosecuted 3 dealers in San Diego this year, charging them when someone overdoses. 2813

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