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WAUWATOSA, Wis. — A 3-year-old in Wisconsin can see for the first time thanks to a new procedure. McKinley Sovey is the youngest person to undergo this type of gene therapy. Her parents Parker and Julie Sovey have been watching her progress."There was that moment when she did look at me for the first time," said Julie. "I was like I think this is working. I can't even really explain it. She's 3 years old and she looks at mom for the first time. It was a really really cool moment and it was the moment I was waiting for."McKinley was born practically blind. The most she could see was the contrast of light. When she was a year and a half, doctors discovered she inherited a retinal disease. "Six months after that FDA approval, and then less than a year after that she's having the procedure, so it's been like rapid fire," Parker said. Dr. Stephen Russell works in the Department of Ophthalmology and Visual Sciences at the University of Iowa Hospital. He performed both of McKinley's eye surgeries with the gene therapy earlier this month. "Complicated drug because it has multiple parts to the drug and complicated surgery because to make sure we delivered the drug to the appropriate tissues," said Russell.Russell said he is basically forcing DNA into the right cell."We had to do a surgery just to put the solution in the appropriate spot, which is in the area underneath the retina," he said. "At that point, it's just fingers crossed that this gene ends up in the spot that it's supposed to," said Julie.The Soveys knew there were risks and potential complications. "It's terrifying," said Russell.They were hoping the therapy would at least help McKinley maintain the little vision she had. After the first eye surgery, mom and dad didn't notice a difference. But it was shortly after the second surgery they knew it worked. Parker said she was moving with a purpose."She walked into the kitchen, pulled a chair out, stood up on the chair and actively feeling like the toaster and the coffee maker like she knew those were there and she wanted to get up and be able to feel them," he said.McKinley's depth perception is also changing."Being able to see things further away has been really neat and it's also been kind of scary because I feel like I'm having to re-childproof the house for a 3-year-old," said Julie."She use to feel around for whatever it was she was eating," Parker said. "Then she'd put her hands in it to see what it was and then she'd put the spoon in it, and then usually it was dumped by the time it got to her face."McKinley will still likely be visually impaired, but her parents said any progress is a bonus."She may no longer need to be a braille reader," Julie said. "I don't know if she'll need to use a cane to navigate."They said their daughter is becoming more confident and her personality is even changing."This is kind of part of medical history," said Julie.McKinley has some checkups scheduled, but doctors hope she won't need another surgery. 3071
WASHINGTON (AP) — The Supreme Court is rejecting an appeal from environmental groups trying to stop President Donald Trump from building a wall on the U.S.-Mexico border, even as other legal action against the wall is ongoing.The justices on Monday left in place a ruling by a federal judge in San Diego who rejected challenges claiming that the Trump administration improperly waived laws requiring environmental and other reviews before construction can begin.The judge in the San Diego case was Gonzalo Curiel. Trump criticized Curiel during the presidential campaign for his handling of fraud allegations against now-defunct Trump University. Trump had already proposed a border wall and suggested the Indiana-born judge's Mexican heritage meant he wouldn't be fair to Trump in the fraud lawsuit. 808

WASHINGTON (AP) — The United States and Israel tracked and killed a senior al-Qaida operative in Iran earlier this year, in a bold intelligence operation that came as the Trump administration was ramping up pressure on Tehran. Four current and former U.S. officials say the operative, Abu Mohammed al-Masri, al-Qaida’s No. 2, was killed by assassins in the Iranian capital in August. Two of the officials, one current and one former, say Israeli agents carried out the operation. Two others say Israel had been involved in surveillance but could not say definitively who pulled the trigger when al-Masri was gunned down in a Tehran alley on Aug. 7, the anniversary of the 1998 bombings of the U.S. embassies in Nairobi and Dar es Salaam. 745
WASHINGTON (AP) — The Justice Department inspector general says his team will conduct a review of the conduct of federal agents who responded to unrest in Portland, Oregon, and Washington, D.C.DOJ Inspector General Michael E. Horowitz announced the probe in a statement Thursday afternoon, saying his office will coordinate with the Department of Homeland Security.The watchdog investigation will examine use-of-force allegations in Portland, where the city’s top federal prosecutor and mayor have publicly complained.In Washington, investigators will look at the training and instruction provided to the federal agents who responded to protest activity at Lafayette Square, near the White House.Among the questions being studied are whether the agents followed Justice Department guidelines, including on identification requirements and in the deployment of chemical agents and use of force.“The review will include examining the training and instruction that was provided to the DOJ law enforcement personnel; compliance with applicable identification requirements, rules of engagement, and legal authorities; and adherence to DOJ policies regarding the use of less-lethal munitions, chemical agents, and other uses of force,” wrote Horowitz.The investigation is in response to requests from congressional Democrats and complaints from the public since the agents were sent to Portland, Horowitz said in his statement. 1428
WASHINGTON, D.C. – NASA announced this week that astronaut Jeanette Epps has been assigned to its Boeing Starline-1 mission.The mission is the first operational crewed flight of Boeing’s CST-100 Starling spacecraft on a mission to the International Space Station.Epps will join astronauts Sunita Williams and Josh Cassada for a six-month expedition planned for a launch in 2021 to the orbiting space lab.This assignment will also make Epps the first Black woman to live and work in space for an extended period of time, CNBC and USA Today report.Epps reacted to the announcement in a video on Twitter, saying she’s looking forward to the mission. While this will be her first time in space, Epps said she’s “flown in helicopters with Sunni flying” and been “in the backseat of a T38 with Josh flying.”Thank you @JimBridenstine! I’m looking forward to the mission.???? https://t.co/h2xIJMK1Ef pic.twitter.com/cSRf1SE4cr— Jeanette J. Epps (@Astro_Jeanette) August 25, 2020 Before joining NASA in 2009, Epps spent seven years as a CIA technical intelligence officer. She has a bachelor’s degree in physics from LeMoyne College, as well as a master’s degree in science and doctorate in aerospace engineering from the University of Maryland, College Park. 1258
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