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HEALDSBURG, Calif. (AP) — Wildfire has been cruel to Northern California wine country lately. Major fires during three of the past four years have charred vineyards, burned down a historic winery and sent plumes of smoke above the neatly tended rows of vines that roll across the scenic hills. While the majority of vineyards, winemaking facilities and tasting rooms that lure tourists have escaped damage, the perception that the area is on fire yet again has not helped business. The LNU Lightning Complex, which includes the Hennessey, Gamble, 15-10, Spanish, Markley, 13-4, 11-16, and Walbridge fires, had burned at least 375,209 acres. Over the last 12 days, the fires have torn through Napa, Sonoma, and Solano counties. As of Sunday, the blaze was 56% contained.Add restrictions on winery tastings and dining during the coronavirus pandemic and winemakers say they are reeling. 892

Hazards created by Hawaii's Kilauea volcano have spawned a lot of questions from the public. How long will this last? Is it safe to be on Big Island right now? Can I roast marshmallows?The US Geological Survey has been answering those questions on social media. Here's a look at some of them. The questions have been edited for clarity and brevity.Q: Is it safe to roast marshmallows over volcanic vents?USGS: Erm...we're going to have to say no, that's not safe. (Please don't try!) If the vent is emitting a lot of SO2 [sulfur dioxide] or H2S [hydrogen sulfide], they would taste BAD. And if you add sulfuric acid (in vog, for example) to sugar, you get a pretty spectacular reaction.Q: Is it safe to be in Hawaii right now?USGS: The eruption at Kilauea right now is impacting a small portion of the Big Island. Lava flows are active on the eastern tip of the island, in lower Puna, and Hawaii Volcanoes National Park is closed due to the small explosions occurring at Kilauea's summit. But the Island of Hawaii is made up of 5 volcanoes, and only Kilauea is erupting.Even if there were to be a change in activity at Kilauea, it would not impact Hilo or Kailua-Kona (the largest towns on the island), which are located on different volcanoes. The biggest impacts might be vog, but that has been a persistent issue on the island for decades. You can actually get real-time vog information at sites around the island from the Hawaii Department of Health at http://www.hiso2index.info/. 1493

Holidays will look different this year for many Americans, with dinners outside, social distancing, or passing on family gatherings altogether. But several companies developing rapid at-home COVID-19 tests are hopeful that won't be the case next year. The goal is to make inexpensive, easy-to-use COVID tests that can deliver results in minutes, just like a pregnancy test. "For people to feel comfortable to associate with friends or family, there needs to be a testing methodology ideally that can be performed at home," said Tony Lemmo, CEO of the manufacturing company BioDot.The company's technology is being used by over 70 manufacturers worldwide making COVID-19 antigen, antibody, and PCR tests. Their automated platforms dispense nanoliter/picoliter amounts of reagent onto the tests accurately and fast.Lemmo says just one of their systems can support the production of roughly 100 million COVID-19 tests per year, helping to make high-volume production possible.“We knew we were going to be called on by customers to manufacture more equipment to provide them the ability to manufacture more tests," said Lemmo. To meet customer demand, BioDot increased staffing and built a new facility, compressing production time from months to weeks. The FDA recently authorized the first rapid at-home test that can deliver results in 30 minutes, eliminating the need for a lab to test the sample. But the molecular single-use test will only be available to patients with a doctor's prescription who are suspected of being infected with COVID-19.Companies developing tests hope the FDA will soon authorize another at-home testing tool: the rapid antigen test.These inexpensive tests provide results within minutes, and companies developing them say millions could be sold without a doctor's referral.“From what we’re hearing, it’s really just a matter of possibly months before there’s at least sufficient data to be able to support an at-home use of a test like an antigen test," said Lemmo.Lemmo says if authorized by the FDA, manufacturers could make millions of these tests in a matter of months. But antigen tests are less accurate, and the FDA wants to ensure they'll be simple enough for people to use at home. There are also concerns over how the data will be reported to health authorities. “I think any at-home testing or massive rollout of a test into the communities needs to be done very carefully and with a lot of education around it," said Clinical Lab Director Melissa Miller. Dr. Miller is a professor of pathology and laboratory medicine at the University of North Carolina Chapel Hill and Medical Director for the Clinical Microbiology Lab for the Medical Center.She worries the inaccuracies of these tests could eventually lead the public to lose trust in all testing. “Even at 98 percent specificity, which is very, very high. That means you’re going to have a false positive two out of every 100. If you started testing a hundred million people, this is millions of people who have a false-positive test," said Dr. Miller. She says this could lead to healthy people isolating and missing work or school unnecessarily, and false-negative results could give people a false sense of security. “These rapid antigen tests were pushed out to skilled nursing facilities; this is a very high-risk patient population. This is actually where you want a very accurate test," said Dr. Miller. She says it’s unclear how well antigen tests detect the virus in asymptomatic patients but agrees more data is needed to figure that out.“It might make more sense for K-12 schools, or even college settings, where there’s less risk for a poor outcome if you have a false positive or a false negative," said Dr. Miller. But with a growing demand for convenient at-home testing, manufacturers are hopeful that in the months ahead, the FDA will soon open the door to new solutions. 3889

HOLLISTER, Calif. (AP) — A magnitude-4.7 earthquake has struck a wilderness area of central California.The U.S. Geological Survey says the temblor occurred at 12:42 p.m. Tuesday and was centered about 16 miles (25 kilometers) southeast of Hollister. The quake occurred at a depth of 6 miles (9.6 kilometers).The epicenter area is in a rugged mountain range, with agricultural areas to the west.Late Monday, the San Francisco Bay Area was rattled by a magnitude 4.5 earthquake.That quake was center near Pleasant Hill, northeast of Oakland but was felt widely.More than 67,000 people posted to the U.S. Geological Survey's citizen reporting web page.Veteran seismologist Lucy Jones says the two quakes are too far apart to be related. 741

General Electric was blasted on Wednesday by workers, retirees and shareholders bemoaning the downfall of the company they love.At its annual meeting, GE got an earful from employees and investors who pleaded with management to right the ship after a disastrous year."I believe it was arrogance and a series of bad business decisions," former employee Bill Freeda said. "Our board of directors clearly has been AWOL."Another shareholder said: "GE, which was once one of the preeminent companies in the world — the bluest of blue chips — is now an embarrassment."The past 12 months has been one of the darkest periods in GE's 126-year history. A cash crisis, brought on by years of bad deal-making, forced GE to cut its dividend in half and lay off thousands of workers. GE's stock price has crashed by 50%, and calls to kick it out of the Dow have grown louder.Despite the deep criticism of past and current GE leaders, the company's nominees to the board were all elected on Wednesday. None of the shareholder proposals calling for reform were adopted, though one pushing for splitting the CEO and chairman roles received strong support.John Flannery, a veteran GE executive who replaced longtime chairman and CEO Jeff Immelt last year, said he remains "extremely proud" of the company despite its "immensely disappointing" results."We're keenly aware of the pain that our performance has caused," he said.Flannery urged investors and employees to keep the faith and said results from the start of 2018 offer hope."I want all of you to be proud of the company and not lose heart," he said. "I assure you we will not let up until this job is complete."Former GE workers slammed the company for eliminating their supplemental health insurance plans."We built the company. We put it where it is today," said Ron Flowers, president of the Retiree Association of General Electric."Don't just think financially," Flowers urged the board. "Think morally also."Other retirees lamented GE's billion pension deficit, the largest among S&P 500 companies. They questioned whether the pension fund, whittled by years of low rates and inattention, will be around to support them.Flannery said the pension fund is running a "significant deficit," but he said maintaining its integrity is "a deep priority for us." He noted GE recently announced plans to contribute billion to the fund.Freeda, a GE retiree, slammed Immelt for having a back-up jet fly around the world with him on some trips. (GE has said it stopped that practice in 2014. Immelt told the board last year in a letter that he "did not have time to personally direct" the day-to-day operations of GE's corporate air team. He said use of the spare plane was halted once he became aware of it.)"Shareowners should wonder: Were there other serious business abuses?" Freeda said. He called for an independent investigation into questionable business practices under Immelt and urged GE to consider clawing back the former CEO's bonuses.Flannery said that the GE board would take "appropriate steps" if "evidence of serious misconduct" were to emerge. A spokesperson for Immelt declined to comment.GE shareholders voiced stronger support for a proposal aimed at boosting oversight by splitting the CEO and chairman roles. About 41% of shares were cast in favor of the bid, up from 24% last year.In light of accounting concerns at GE, shareholder support for KPMG as the company's auditor dropped sharply. Just 65% of shares were cast in favor of ratifying KPMG, down from 94% last year. KPMG has been inspecting GE's books for 109 years, leading critics to argue they've become too cozy.Martin Harangozo said he was fired by GE with no severance after raising questions about "bad" accounting."GE transitioned from an honest company to a dishonest company," Harangozo said.Underscoring the challenges facing GE, Moody's lowered its credit outlook on the conglomerate to negative on Wednesday because of the expected costs of a Justice Department investigation into its subprime-mortgages business.Moody's warned it could downgrade GE's credit rating if the company fails to improve cash flow significantly or if revenue keeps shrinking at the beleaguered power division. GE shares dropped nearly 5% on Wednesday, leaving them down 53% over the past year.One retiree pleaded with Flannery to turn around the company — fast."My whole life has been GE," he said. "Give it all you've got. We're with you." 4465

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