济南有痛风能要孩子吗济南尿酸高出正常值多少会痛风,山东女人有得痛风的吗,济南痛风艾灸可以吗,济南治痛风花多少钱,山东痛风还能运动吗,山东手上的痛风石能去掉吗,济南痛风治疗的好方法有哪些

SAN DIEGO (KGTV) — It's a weekend packed with Oktoberfests across San Diego County as October and the fall season kicks into fear.El Cajon, La Mesa, Carlsbad, and Julian all celebrate Oktoberfest this weekend, with fun fall festivals featuring delicious brews, games, folk music and dancing, and German cuisine.If you're looking for some early scares, Balboa Park's Haunted Trail is open for the season. Head to the park if you dare for a hike like none other.SAN DIEGO HALLOWEEN:Frightful fun: San Diego Halloween, fall events for familiesExperience Halloween chills at these San Diego attractionsSpirited shindigs: Halloween parties for San Diego's 21+ crowdPacific Beach and Mira Mesa also welcome the community out this weekend for their own street fairs, with live music, arts and crafts, and more fun in the sun.THURSDAYOktoberfest in El CajonWhere: German American Societies of San Diego; Cost: - (Thursday - Sunday) Enjoy live German "Oom-Pah" music, traditional foods like bratwurst and ox-on-the-spit, German beers, folk games and dancing, and a kids' zone at El Cajon's massive Oktoberfest party.Haunted Trail at Balboa ParkWhere: Marston Point; Cost: - (Thursday - Sunday) Prepare for a scare as you walk down the mile-long trail. The theme for 2019 is “Stranger Things” and features the swampy fog of the upside down. Pregnant women and young children are banned from entry.FRIDAYFall Home Garden ShowWhere: Del Mar Fairgrounds; Cost: Free - (Friday - Sunday) Get all you need to spruce up your home and garden for fall at the Del Mar Fairgrounds this weekend for the annual Fall Home Garden Show. Guests can put together their own succulents, get tips from design and gardening experts, check out seasonal foliage, and more.La Mesa OktoberfestWhere: La Mesa Village; Cost: Free to attend(Friday - Sunday) La Mesa Village claims their Oktoberfest is the largest this side of the Mississippi. Head over for three-days of traditional sing-a-longs, original glücklich games like stein races and keg bowling, contests and crafts, and traditional German dishes and food.SATURDAYPacific BeachfestWhere: PB Boardwalk, from Felspar St. to Thomas St.; Cost: FreeHit the Pacific Beach boardwalk for a festival on the sand, with multiple stages of live music, arts and crafts village, kids zone, beer garden, fish taco contest, and more to check out. The day kicks off with a 5K and volleyball tournament and runs through to a beautiful beach sunset.Mira Mesa Street FairWhere: Camino Ruiz, from Mira Mesa Blvd. to New Salem St.; Cost: FreeEnjoy live music across two stages, international foods, kids activities and inflatables, and more at the Mira Mesa Street Fair this weekend. The US Marines will be on hand to give visitors a look at their explosive ordinance disposal robot and visitors can take a peek into a solar telescope. Carlsbad Oktoberfest and Family Fall FestivalWhere: Holiday Park; Cost: Free - Not only can you enjoy Oktoberfest in Carlsbad, but help support the local Rotary Club. The event hosts costume contests, arts and crafts, games and rides, live music, and delicious authentic German meals and brews.SUNDAYKSON's CountryFestWhere: Del Mar Fairgrounds; Cost: - Grab your favorite pair of boots and head down to Del Mar to see country music stars Billy Currington, Blanco Brown, Jon Langston and Dillon Carmichael perform. Line dancing will surely be in the mix along with fun games and delicious foods and drink.Rendezvous in PowayWhere: Old Poway Park; Cost: Varies(Saturday - Sunday) Living history groups help bring the 1800's alive in Poway, where the annual Rendezvous in Poway gives visitors the chance to pan for gold, experience western reenactments, peruse handcrafted arts, and learn more about the west's early history.Oktoberfest in JulianWhere: Julian Town Hall; Cost: Free to attend(Saturday - Sunday) Julian hosts a fun-filled Oktoberfest and fall celebration with live traditional folk and polka music, craft booths, raffles for prizes, and delicious German cuisine and Julian treats. 4062

SAN DIEGO (KGTV) -- Isabel Rosales was brutally attacked and nearly killed by her husband in January 2018."It was life or death, my ex husband attacked me in front of my kids," said Rosales.Rosales was married for 16 years. She and her ex-husband moved from Chicago to San Diego for a fresh start. But Rosales says the abuse only got worse."Sexual abuse, verbal abuse, physical abuse, everything," said RosalesShortly after their 16-year anniversary Rosales told her Ex-husband she wanted a divorce. She barely made it out of the family home alive."I was getting ready to go to work and we had been arguing...his behavior had been kind of erratic over the last few weeks. I thought he was agreeing with me when he said it ends here. I thought he was getting his suitcase and leaving. He followed me into the bathroom and he stabbed me. I ran into the kid's room and he stabbed me in front of the kids who were sleeping. I was able to push him out of the way and I ran out of the house. Before I ran out of the house though he attacked me again at the front door. I knew if I didn't make it out of the door it was over and by the grace of God the door opened."Rosales was in the ICU at UCSD for three days with a breathing tube. She says she fought to stay alive for her three children and her mother, who was killed by her boyfriend in 2011."My mother was murdered by her boyfriend in Mexico. And my ex-husband attacked me in a very similar way."Rosales says she had what her mother did not. Help. Hers came in the form of Operation for Hope, a San Diego non-profit that helps provide emergency services to victims of domestic abuse. Rosales was given emergency shelter and money to pay for a divorce attorney."It helped me have a future. It gave me exactly what it promises- HOPE."Rosales has this advice for other survivors."I was ashamed to ask for help. I didn't know services like this exist. I am here to tell you there's great courage in asking for help and taking that first step... I hope and I pray to change one other person's world out there by sharing my story. My heart aches for those who do not make it like my mom, for those who do not know how to get out or where to go, for those that think an abusive relationship is normal. Anything is possible and each and every person is deserving of a beautiful and safe life... I am happy now. These tears are tears of joy."During the pandemic, domestic violence incidents have increased. From January to June 2020, there were 8,495 domestic violence incidents reported to law enforcement in San Diego County, as compared to 8,235 during the same period in 2019; a 3% increase from the prior year according to the San Diego County District Attorney's office. The Victim Assistance Program advocates at the District Attorney's office served 2,940 victims from March-July 2020, as compared to 1,941 in 2019; a 51% increase in those served.Operation for Hope will hold it's biggest fundraiser of the year October 28, 20202. 10News Anchor Vanessa Van Hyfte will be emceeing the live event and silent auction. All of the money will go directly to benefit victims and survivors of domestic abuse in San Diego County.For more information click here. 3210

SAN DIEGO (KGTV) — It's going to be a great weekend to get outside and enjoy the fall season in San Diego!Believe it or not, the Christmas season has already begun as the Old Globe Theatre brings "Dr. Suess's How the Grinch Stole Christmas" back to the stage. Tickets are on sale for show times throughout the month!Also, SnowJam takes over Del Mar this weekend, packing heavily discounted and new gear and clothing, lift tickets, and more into the Del Mar Fairgrounds just before snow hits the slopes.Not interested in anything here? Check out the 10News?community events calendar for a look at even more things to do!Beer and food fans get their fill as well, with San Diego Beer Week continuing, Stone's DRK Festival, and the San Diego Bay Wine and Food Festival!Plus, Veteran's Day festivities hit town in celebration of our armed forces! Here's a look at what's happening this weekend:THURSDAYDr. Suess's How the Grinch Stole ChristmasWhere: Old Globe Theater; Cost: - (Runs Thursday - Sunday) That's right. The Grinch is back in San Diego! The Old Globe's production of "How the Grinch Stole Christmas" returns, bringing the classic Christmas tale of the Grinch's plan to ruin Whoville's holiday fun to the stage. San Diego Asian Film FestivalWhere: Various locations; Cost: - (Runs Thursday - Sunday) Enjoy San Diego's showcase of Asian American and international works of cinema as the San Diego Asian Film Festival this weekend! The festival brings an opening night party on Thursday followed by short film screening and special presentations! FRIDAYStone DRK FestivalWhere: Stone Brewery, Escondido; Cost: Fan on the dark brews? Stone, while known for its IPAs, is celebrating its darker pours during Stone DRK Festival. A ticket gets beer fans tasters, a commemorative glass, and tastes of some of the breweries favorite and rare beers! SnowJam?Ski & Snowboard ExpoWhere: Del Mar Fairgrounds; Cost: - (Runs Friday - Sunday) The latest and greatest in snow gear is waiting at Del Mar this weekend, as SnowJam comes to town. Check out heavily discounted, brand new equipment and clothing and lift tickets, and check out live demonstrations or talk with industry reps. Just in time for ski season!  SATURDAYSan Diego Veteran's Day ParadeWhere: San Diego Embarcadero; Cost: FreeCelebrate our nation's veterans and active-duty military members during San Diego's annual Veteran's Day parade! Service members will travel down Pacific Highway, past the USS Midway, in celebration of our nation's heroes. San Diego Beer WeekWhere: Various locations; Cost: Varies(Runs Friday - Sunday) Local craft beer fans can visit participating restaurants, bars, and breweries for special beer releases and events highlighting why San Diego is considered the capital of craft beer. 6th annual Ride the Point 2018Where: Oggi's Pizza and Brewing, San Diego; Cost: - Pedal for a cause along Point Loma in support of pancreatic cancer research! The annual Jim Krause Memorial Charity Bicycle Ride starts at Liberty Station and takes riders on a scenic path through Point Loma. The public is also invited to the race's free healthy lifestyle expo at the event!  SUNDAYSilver Strand Half Marathon & Veteran's Day 5KWhere: Sunset Park, Coronado; Cost: - Show your support for our nation's military during the Silver Strand Half Marathon! The run starts and finishes at Imperial Beach Pier Plaza, and treats runners and walkers to a post-race beach party and beer garden at the end! BOOmont Park and Fall FestWhere: Belmont Park; Cost: Free - Halloween may be over but Fall fun is still here! Belmont Park will continue its Boomont Park and Fall Fest this weekend, with free trick-or-treating, costume contests, entertainment, pumpkin painting, and much more. San Diego Bay Wine and Food FestivalWhere: Embarcadero Marina Park North; Cost: 5 - 5Treat your taste buds to bites from more than 60 celebrity chefs and restaurants, and sips from hundreds of wines and spirits during San Diego Bay Wine and Food Fest! San Diego's top chefs will be churning out delicious creations over the course of an entire week. 4261

SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459

SAN DIEGO (KGTV) - Inside a mobile machinist shop, the Marine Corps can now print polymer and metal parts on the go.Operated by the 1st Marine Logistics Group, the Expeditionary Manufacturing Shelter is currently at Camp Pendleton. It houses several 3D printers which each serve a specific purpose."Digital manufacturing can be extremely useful in a combat situation or a disaster zone because we can take this shelter and deploy it to anywhere it's needed. We're able to provide parts that are not readily available, and we're able to get our equipment operational faster," said Staff Sgt. Samuel Margarini.Rather than ordering a part and waiting up to a week, the Marines can re-create a part within 24 hours, improving readiness and operational momentum.3D printing new parts is also cheaper and saves resources. "Since implementation we've had a huge impact on different platforms, we've made parts for trucks, humvees, tanks, and some drones," said Margarini.While only being used in training, for now, shelters like this will eventually be deployed where needed by the Marine Corps. 1098