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WASHINGTON, March 4 (Xinhua) -- New data suggest that the epilepsy drug Topamax (topiramate) and its generic versions increase the risk for the birth defects cleft lip and cleft palate in babies born to women who use the medication during pregnancy, the U.S. Food and Drug Administration (FDA) said Friday in a statement.Before prescribing topiramate, approved to treat certain types of seizures in people who have epilepsy, health care professionals should warn patients of childbearing age about the potential hazard to the fetus if a woman becomes pregnant while using the drug, the FDA said.Topiramate also is approved to prevent migraine headaches, but not to relieve the pain of migraines."Health care professionals should carefully consider the benefits and risks of topiramate when prescribing it to women of childbearing age," said Russell Katz, director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. "Alternative medications that have a lower risk of birth defects should be considered."Cleft lip and cleft palate, collectively called oral clefts, are birth defects that occur when parts of the lip or palate do not completely fuse together early in the first trimester of pregnancy, a time when many women do not know they are pregnant.The defects range from a small notch in the lip to a groove that runs into the roof of the mouth and nose, possibly leading to problems with eating, talking, and to ear infections. Surgery often is performed to close the lip and palate and most children do well after treatment.Data from the North American Antiepileptic Drug (AED) Pregnancy Registry indicate an increased risk of oral clefts in infants exposed to topiramate during the first trimester of pregnancy. Infants exposed to topiramate as a single therapy experienced a 1.4 percent prevalence of oral clefts, compared with a prevalence of 0.38 percent - 0.55 percent in infants exposed to other antiepileptic drugs.Infants of mothers who did not have epilepsy and were not being treated with other antiepileptic drugs had a prevalence of 0.07 percent. Similar data from the United Kingdom Epilepsy and Pregnancy Register supported the North American AED Pregnancy Registry data.According to the FDA, before starting topiramate, pregnant women and women of childbearing potential should discuss other treatment options with their health care professional.
BEIJING, March 7 (Xinhua) -- The Chinese currency Renminbi (RMB), or the yuan, on Monday strengthened to an all-time high of 6.5651 per U.S. dollar, according to the China Foreign Exchange Trading System.Monday's central parity rate of the RMB against U.S. dollar was 20 basis points lower than the previous record of 6.5671 set on last Friday.The yuan has appreciated 3.84 percent since June 19 last year when the People's Bank of China, the central bank, announced it would further reform the exchange rate formation mechanism to improve its flexibility.On China's foreign exchange spot market, the yuan can rise or fall 0.5 percent from the central parity rate each trading day.The central parity rate of the RMB against the U.S. dollar is based on a weighted average of prices before the opening of the market for each business day.
BEIJING, Jan. 22 (Xinhua) -- Chinese President Hu Jintao's latest state visit to the United States bore rich fruit and opened a new chapter of cooperation between the two countries, Foreign Minister Yang Jiechi said Saturday.The tour, from Tuesday through Friday, came at the beginning of the second decade of the 21st century, on the 40th anniversary of the resumption of contact between the two countries and on the opening year of China's 12th five-year plan for national socioeconomic development, Yang noted.Meanwhile, the international situation was witnessing deep and complicated changes, and the China-U.S. relationship was forging ahead with increasing momentum while inevitably encountering some differences and disputes, he said.Against such a backdrop, the Chinese president held frank and in-depth talks with his U.S. counterpart, Barack Obama, and many other senior political figures, and reached important consensus on bilateral relations and a host of major regional and global affairs, Yang said.During the tightly scheduled trip, which saw Hu attend nearly 20 events in Washington and Chicago within 68 hours, the Chinese leader also reached out to the U.S. public, conveying China's resolution to advance China-U.S. ties, highlighting China's commitment to peaceful development and presenting China's image of peace, development, opening-up and progress, Yang said.The U.S. and international media, he added, attached great importance to and spoke highly of Hu's trip, hailing it as a historic visit at a crucial moment and whose significance was manifested partly in the top level reception with full pomp and ceremony given by the U.S. government.In summary, the latest step in China-U.S. diplomacy achieved rich results and cast a far-reaching influence not only upon the two countries themselves but upon the whole world, the Chinese foreign minister said.
BEIJING, Feb. 8 (Xinhua) -- China would continue expanding its radio and television networks coverage in the country's rural areas in the 2011-2015 period, according to the State Administration of Radio, Film and Television (SARFT).In the five-year period, efforts would focus on ensuring access to radio and TV services in those villages with less than 20 households, the SARFT said in a statement.It noted that China's other villages which had more than 20 households were already covered by the radio and TV networks, thanks to government's continuous efforts in this regard.China's central and local governments poured over 15.7 billion yuan (2.38 billion U.S. dollars) into the upgrading of the radio and TV networks in the country's rural areas in 2006-2010.Official figures indicated that 96.31 percent and 97.23 percent of China's population had access to radio and TV services respectively in 2009. The ratio was 86.02 percent and 87.68 percent respectively in 1997.
SHANGHAI, March 17 (Xinhua) -- Lenovo Group and a subsidiary of Shanghai Media Group (SMG) signed an agreement on Thursday to create a firm that would provide mobile-Internet video services.BesTV New Media Co., a subsidiary of SMG, owns 51 percent of the venture, named Shanghai Video Cloud Company Limited, while Lenovo owns the remainder. The total investment of both parties in the new firm exceeded 10 million yuan (1.52 million U.S. dollars), according to the agreement.Lenovo is currently the largest personal computer maker in China. BesTV New Media is a provider of Internet Protocol Television (IPTV), mobile television and other forms of new media.