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LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283

JACKSON, Miss. (AP) — Kanye West will appear as a presidential candidate on Mississippi's ballot in November, after being approved as a qualified candidate by the State Board of Election Commissioners. The rapper has already qualified to appear on the ballot as an independent candidate in several states, including Arkansas, Idaho, Iowa, Tennessee, Oklahoma, and Utah. He filed to appear on the ballot in Kentucky on Friday.West failed to appear on ballots in Virginia, Ohio, New Jersey, Missouri, and Wyoming. To qualify in Mississippi, he was required to pay a ,500 fee to the Secretary of State's Office and get the signatures of at least 1,000 Mississippi voters. West, who once backed Republican President Donald Trump, announced last month that he had broken with Trump and would launch his own presidential bid. His campaign filed paperwork on July 15 with the Federal Election Commission. 907

JAMUL (CNS) - A fire of unknown origin damaged a home in a back-country neighborhood west of Barrett Lake today and left a resident with burn injuries.The blaze in the 17000 block of Lyons Valley Road in Jamul erupted shortly before 3 p.m., according to Cal Fire.It took crews about an hour to fully subdue the flames, said Issac Sanchez, a fire captain with the state agency.Medics took a 25-year-old man to UCSD Medical Center in San Diego for treatment of burns of undisclosed severity.The cause of the fire was under investigation, Sanchez said. 557

Just three weeks before facing voters, Sen. Kamala Harris questioned Judge Amy Coney Barrett for 30 minutes during Barrett’s Supreme Court confirmation hearing on Tuesday.Harris, Joe Biden’s running mate and Democratic candidate for vice president, largely used her allotted time to point toward President Donald Trump’s campaign goal of eliminating the Affordable Care Act.Democrats, like Harris, have zeroed in on their belief that Barrett would vote to dismantle the Affordable Care Act, which was passed by a Democratic Congress and signed by President Barack Obama nearly a decade ago.Just one week after the election, the Supreme Court will hear another GOP-led challenge to the law. In 2012, the Affordable Care Act was “saved” in a 5-4 ruling by the Supreme Court as justices said that the law should stand as it levied a tax penalty for those without health care. In 2017, the individual mandate was struck down, meaning there is no longer a tax penalty component to Obamacare. Now the argument comes back to the Supreme Court, as Republicans claim the court's previous ruling is moot given there is no longer a tax penalty.Harris pointed to a previous op-ed pinned by Barrett when she was a law professor at Notre Dame to claim Barrett would rule against Obamacare. Barrett wrote that the Affordable Care Act should have been overturned in 2012."You've already opined the constitutionality of the Affordable Care Act. And that position satisfied the president's promise to only nominate judges who would tear down the Affordable Care Act,” Harris said.Barrett fired back, and added that she has made no commitment to the Trump administration on overturning the act.“Question would be figuring out whether Congress, assuming that the mandate is unconstitutional now, whether that consistent with your intent,” Barrett said.Harris then pressed Barrett on her views on Roe vs. Wade. Barrett said multiple times throughout the hearing that she would not offer an opinion on the 1970s-era ruling that largely has kept abortion legal throughout the US.“I would suggest that we not pretend that we don't know how this nominee views a woman's right to choose,” Harris said.Harris was questioned by Mike Pence at last week’s vice presidential debate on whether her and Biden would be supportive of expanding the Supreme Court. Harris avoided the question, and Biden had largely avoided the question until last night, stating he was not supportive of expanding the Supreme Court. 2487

JOHANNESBURG (AP) — Zindzi Mandela, the daughter of South African anti-apartheid figures Nelson Mandela and Winnie Madikizela-Mandela, has died aged 59. State television the South African Broadcasting Corporation has reported that Mandela died at a Johannesburg hospital early Monday morning. At the time of her death, she was South Africa's ambassador to Denmark. The Mandelas' daughter came to prominence in 1985, when the white minority government offered to release Nelson Mandela from prison if he denounced violence perpetrated by his movement, the Africa National Congress, against apartheid, the brutal system of racial discrimination enforced in South Africa at that time. His letter rejecting this offer was read by his young daughter Zindzi at a packed public meeting and broadcast around the world. 818