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SAN DIEGO (KGTV) — It has now been seven months since the pandemic began, and there are still a lot of questions about the best ways to treat patients with COVID-19.Researchers at UC San Diego are leading an effort to produce swift and reliable answers that could help doctors tailor treatments and hospitals plan bed space more efficiently.Doctors agree: the best way to fight any disease is to tailor the treatment for each individual based on their age, gender, race and other factors. But how does one doctor do that with a new disease like COVID-19, especially if their hospital has only seen a few hundred cases?“There might be some patterns you can get from 500 patients but there might be some others that you cannot,” said UCSD professor Dr. Lucila Ohno-Machado, chair of the Department of Biomedical Informatics.Dr. Ohno-Machado’s solution? Pool data.She’s leading the charge behind COVID19questions.org, a collaboration between 12 medical systems spanning more than 200 hospitals across the country.The collaboration includes several University of California health systems, the University of Texas Health Science Center at Houston, the University of Colorado Anschutz Medical Campus, and the largest organization in the cohort, the Veterans Affairs Healthcare System.“Each hospital is a little small to answer the questions. So by having it all together, we get the answers quicker,” said Ohno-Machado.They’re going after answers on how long patients with diabetes or cancer stay in the hospital, and whether COVID-19 is deadlier for smokers or non-smokers.Their findings revealed that men are much more likely to wind up on a ventilator than women.And they quantified just how much better we’ve gotten at treating COVID-19 over time.Since May 1, hospital stays among surviving patients have shrunk more than 10 days on average. That’s important for hospital managers planning and predicting bed space.“We decided to open this to the public and to our colleagues, and then we pick which answers have not been answered before and seem to be of most general interest,” Dr. Ohno-Machado explained.If this sounds like a straightforward approach, it’s not. Patient confidentiality laws make it hard for hospitals to share data and the information released by the CDC is limited.Maintaining patient confidentiality while sharing granular data is the most groundbreaking feature of the collaboration, called Reliable Response Data Discovery or known by its Star Wars-inspired acronym, R2D2.UCSD said R2D2 differs from other patient databases and registries because each health system maintains control of data rather than sharing it in a central repository. Through advanced computer techniques, each partner agency shares aggregated data, not patient-level information.The collaboration’s research is based on what’s called “observational data,” so Dr. Ohno-Machado said it’s not a replacement for a randomized, controlled clinical trial, which takes time. She noted their data reflects lessons on hospitalized patients, not everyone infected with the virus.But she said at a time when fast answers can save lives, COVID19questions.org could help. 3161

SAN DIEGO (KGTV) -- Mayor Kevin Faulconer Saturday detailed plans to redevelop the Sports Arena site, officially announcing what developers will tackle the project.According to Faulconer, the plan incorporates a mix of entertainment, housing, and parks."The vision for this property is for a world-class arena, park space and amenities," Faulconer said. "A new arena has always been a priority of mine, and it's the right time."Brookfield Housing and ASM Global were chosen to construct the new arena and thousands of housing units, beating out the other finalist, Toll Brothers Housing.The redevelopment area encompasses roughly 48 acres in the Midway-Pacific Highway Community area. At the press conference, representatives from the Gulls and the Seals spoke, saying they're excited for their teams to play in the new space. Faulconer said the city's goal is to include a new arena to replace Pechanga Arena."The vision for this property is for a world-class arena, park space and amenities," Faulconer said. "A new arena has always been a priority of mine, and it's the right time."The city also released several renderings of the planned development. Leaders said they are now looking toward November when Measure E will be on the ballot. This will determine if the 30-foot maximum height for buildings will remain, or if it will be raised. This will impact how tall the new facilities will be.San Diego Loyal SC, which had plans to build a modular soccer stadium at the site, commented on the announcement following the news conference. "Though the news from the city today felt like a punch in the gut, years being married to the sport of soccer has taught me that sometimes you can win on the field and not get the result that matters. I have also learned that tomorrow will come, and we will rise again,” said SD Loyal President Warren Smith. City News Service contributed to this report. 1905

SAN DIEGO (KGTV) - Immigration rights advocates in San Diego are worried about the impact of President Trump's promised mass deportation. In a pair of tweets Monday night, President Trump said that U.S. Immigration and Customs Enforcement would next week "begin the process of removing the millions of illegal aliens who have illicitly found their way into the United States."Benjamin Prado is the program coordinator for the U.S. Mexico Border Program with the American Friends Service Committee. Prado says the tweets are causing concern and confusion.“We’re not sure because of the tweets, they are just so random, and very limited in scope and depth," said Prado. ICE agents carried out an immigration crack down at the Zion Supermarket in Clairemont Mesa back in February. Twenty-six workers were detained. "Our communities have experienced all kinds of things, whether it be on transportation, roving patrols, that border patrol has done in the past,”said Prado. He said his members started watching their communities long before the president's latest tweet. "Our community members are mobilizing, have been mobilizing even before this tweet, and have been out in the community, making sure Immigration and Customs Enforcement doesn’t go and separate families," said Prado. Immigration attorney Edward Orendain said the enforcement action would likely target people who have skipped out on their hearings or who have been given final deportation orders. "Apparently, this is going to be targeted more toward people who already have outstanding deportation orders or orders of deportation. Initially, that may seem to be a good thing, but I know, because I have several clients, that a significant number of the people who already have final orders of deportation are under supervised release, which means local immigration already knows of them, but they’re allowed to stay in the United States usually for humanitarian purposes," said Orendain. Orendain says he has one client, who was given final deportation orders, but is on supervised release because she has an ill son who is a U.S. citizen. "She's been removed a couple of times, but she has a U.S citizen child who has severe medical and developmental issues and really can’t get the standard of care in his home country,so the government knows about her, knows that she has final orders of removal or deportation, but allows her to stay here as a humanitarian issue," said Orendain. It's estimated more than 200,000 undocumented workers are in San Diego County. Orendain said he hopes the president's tweet has more to do with politics than any actual plan. "Maybe it was a way to stoke the fires in his base, but because of the office that he holds, it has to be given attention." 2758

SAN DIEGO (KGTV) — In their push to reopen schools, some political supporters of President Donald Trump have cited COVID-19 research from a group of San Diego scientists, claiming it’s evidence we could be close to herd immunity from the virus.But one of the authors of that research says that conclusion is way off.One of the most prominent supporters of the herd immunity conjecture is Dr. Scott Atlas, a neuroradiologist and senior fellow at Stanford University’s Hoover Institution who became an adviser to President Trump this month.“There’s a pretty good chance that herd immunity requires way less infections because of existing immunity out there,” Atlas said in a livestream conversation with San Diego County Supervisor Jim Desmond. “It actually may have already been reached in places like New York. We don’t know, but it’s possible.”Herd immunity is the level of protection needed to effectively stop the virus from circulating, thought to be about 70 percent of the population. The “existing immunity” to which Atlas is referring has to do with T cells.“It's just a misunderstanding of the science,” said Dr. Shane Crotty, a virologist at the La Jolla Institute for Immunology who co-authored the groundbreaking research on T cells in June.Crotty and his colleagues found that 50 percent of people unexposed to the novel coronavirus had T cells that could recognize it. Scientists refer to this as cross-reactive T cells, and the study was replicated in other countries.Proponents of the herd immunity theory take the number of people infected with the coronavirus, add the number of people with T cells that can recognize the virus, and come up with a number around the herd immunity threshold of 70 percent. But the math doesn’t work that way, according to Crotty, in part because T cells only kick in once a virus has hijacked cells, meaning T cells alone can't stop a pathogen in its tracks.“We’re not saying those 50 percent of people have protection like they’ve already had the virus,” Crotty said. “We’re saying those 50 percent of people have a head start in responding to the virus, which is a good thing but doesn’t affect herd immunity.”Since the novel coronavirus is a new pathogen, scientists did not expect people would have tools in their immune system capable of recognizing it. Unexposed people do not have cross-reactive antibodies, Crotty said.But in a study published this month in Science, Dr. Crotty and his colleagues offered a potential explanation for the surprising T cell results: they found these cross-reactive T cells also recognized four other coronavirus strains that cause common colds.Their theory: the T cells were created in response to other coronaviruses but can recognize SARS-CoV-2 like a distant relative.“It's a memory of a cousin,” Dr. Crotty said.That memory may speed up the body’s immune response, which can normally take about a week for an unknown pathogen, Crotty said. But scientists aren’t sure yet what role T cells actually play in clinical outcomes.“We have no data and and neither does anybody else as to whether these T cells really help or not,” Crotty said.To answer that question, scientists would need blood samples for lots of healthy people and then they would have to closely study individuals who got infected.The La Jolla Institute for Immunology is raising money for that kind of research, Crotty said, but they’re not there yet. 3417

SAN DIEGO (KGTV) - Kelvin Barrios, a candidate for the San Diego City Council's 9th District, has announced he has contracted coronavirus."After being hospitalized two days ago, I have tested positive for COVID-19," Barrios said in a Facebook post. "While I have been following all social distancing and self-isolation recommendations, I had what I thought was a normal flu for about a week," he said.Barrios described feeling "bad body aches, sweating, headaches, labored breathing, high blood pressure, and an elevated heart rate.""I strongly urge everyone to practice social distancing and stay safe and healthy during these times," he said. 652