山东痛风哪里开始痛(山东痛风疾病怎么回事) (今日更新中)

New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967

New details in the case of 13-year-old Patricia Alatorre who was allegedly raped and murdered last week by a man from Los Angeles who she communicated with on social media. The details in those court documents are very graphic, much of which wouldn't be appropriate to release.It was in the neighborhood near Wible Rd and Hosking Ave where police say 13-year-old Patricia Alatorre was kidnapped near her home last week. Documents revealed a lot of information about how she communicated with her suspected 24-year-old killer, the kind of communication they had prior to her death, and the tragic way she lost her life."That's sad. That's unacceptable. We don't want anybody killed, but it's incredibly sad when people kill children," said Kern County District Attorney Cynthia Zimmer.Zimmer shared her thoughts after court documents were released Wednesday morning detailing the tragic events leading up to Alatorre's death. Officials said she was killed in South Bakersfield shortly after midnight on July 2nd after 24-year-old Armando Cruz from Inglewood communicated with her on social media over the course of a week. They would send explicit photos to each other, according to documents.Things would take a turn for the worst, according to Bakersfield Police Sgt. Robert Pair."As you can imagine this is a particularly sensitive case. It's involving details that is especially graphic."Documents state Cruz convinced Alatorre to meet with him to engage in explicit acts on two occasions despite knowing she was only 13. He drove from Los Angeles to Bakersfield to meet her. On the second encounter, Cruz drove her around the block as she screamed, telling him she didn't want to go with him.It was about this time documents state she was raped. She tried to get up and physically struggled with Cruz and that's when he allegedly strangled her and tied her up with duct tape. He then took her body with him but the details following are too graphic to release.On Sunday night Cruz was arrested by BPD in Los Angeles County and brought back to Bakersfield. On Tuesday he was charged with 12 felony counts."The first count is first-degree murder and in connection with first-degree murder, I charged four special circumstances which carry the penalty of life without the possibility of parole, in prison, or the death penalty," explained Zimmer.Cruz has pleaded not guilty to that first-degree murder charge and all other felony charges, including kidnapping, and aggravated sexual assault. He is due back in court on July 30th. 2538

NEW YORK -- An officer with the New York Police Department was suspended Sunday night after viral video showed police use an apparent chokehold on the boardwalk in Far Rockaway.Four officers were on top of the man and one officer had his arm wrapped around the man. The officer got up after another officer tapped him on the back and appeared to pull at the back of his shirt."While a full investigation is still underway, there is no question in my mind that this immediate action is necessary," NYPD Commissioner Dermot Shea said.Mayor Bill de Blasio said it was the fastest he'd ever seen the NYPD discipline an officer."This is how it needs to be," he said. "The officer who intervened to stop his colleague did exactly the right thing. I commend him. That is what we need to see from all our officers."Lori Zeno, the man's attorney, said she thinks her client would have been choked to death if the officer hadn't been stopped.After the video surfaced, an NYPD spokesperson said it was being taken "extremely seriously" and that there was an active investigation underway by the Internal Affairs Bureau.Police got a call for a man being disorderly on the boardwalk near Beach 113th Street on Sunday morning, officials said. Officers said he was acting erratically when they arrived and resisted when they tried to take him into custody.Body camera video from the NYPD shows a lengthy interaction between police and men on the boardwalk before the start of the viral arrest video."Oh man, this is fun," an officer can be heard saying.The three pedestrians continue talking to police."Touch any of my boys and you are dead," the man who was eventually put into an apparent chokehold said.One of the other pedestrians chastised the man, saying he doesn't disrespect police.About 10 minutes after the confrontation began, police took down the man who'd threatened him. It appears he may he have taken something from a recycling bin right beforehand."Stop choking him! Stop choking him! Let him go," the other pedestrians screamed.After being put in an apparent chokehold, the man was walked to an NYPD vehicle where he told police has was bipolar.While still on the boardwalk, bystanders confronted police."He grabbed something and squared off and was gonna hit my officer who's standing over there," an officer can be heard saying. "That's when everything changed. The minute I saw him flex on him, that's when he goes down because we don't get hurt."The man was treated at a local hospital, police said. Zeno said he was a visible wound on the back of this head.Charges against the man are pending, police said. It's not clear what the NYPD intends to charge him with, but the man's attorney said it's the suspended police officer who should be charged."He's an idiot and he's a bad cop and he needs to go," Zeno said. "He needs to get fired and needs to get prosecuted."Mayoral spokesperson Freddi Goldstein called the video "very concerning.""We’re glad the NYPD is immediately launching an investigation to get to the bottom of what happened," she said.Queens District Attorney Melinda Katz said her office is also investigating."There must be zero tolerance for police misconduct," she tweeted. "The Queens District Attorney's Office is aware of the incident in Far Rockaway today. We take these allegations very seriously and an active investigation is underway."Just days ago amid ongoing protests over police brutality, Gov. Andrew Cuomo signed several police accountability measures into law, including a ban on police chokeholds. The NYPD banned chokeholds in the 1990s.Warning: Video of the incident may be disturbing to some. Police also shared body camera video. 3685

NEW YORK (AP) — Martha Stewart's first Uber ride was not a good thing.Stewart ordered the "most expensive version" Monday outside Tiffany's flagship store in New York City. As Stewart explained on Instagram , she wanted to be picked up on Fifth Avenue and 57th Street.Stewart wrote the first car did not show up and the second parked "halfway down" the street where she "could not see the license plate." That car was pointed in the wrong direction, delaying her journey as the car snaked through midtown Manhattan traffic.But the worst part was the car "was a mess inside and out!!!!!!!!" She posted a picture that showed debris on the floor and two water bottles.Uber says it was disappointed to hear about Stewart's first experience and has reached out to her and her team. 794

NOGALES, Mexico — Eighteen-year-old Joshua escaped violence in Guatemala with his father two months ago and has ended up just steps away from the U.S.-Mexico border.Saying that gangs control almost all of Guatemala, he says they will likely request asylum in the United States.The Kino Border Initiative, headquartered in Nogales, Arizona, helps provide for those fleeing danger who end up like Joshua: far from home and uncertain about the future."A lot of people are fleeing violence in the northern part of Central America and parts of southern Mexico," said Fr. Sean Carroll. "That reality is not changing."Immigration figures show that before 2013, only one in 100 asylum seekers was able to convince authorities they faced a credible fear of violence in their home country, a crucial step toward qualifying for asylum.Now, one out of every ten applicants is able to meet that standard.The asylum process has been under intense political scrutiny as thousands of people have organized into large groups and moved to seek a better life in the United States.The caravans have drawn increasing criticism from President Trump and others in the White House, who have looked for ways to thwart the migrants' ability to enter the U.S. or request asylum.For Joshua, he says he has one request for immigration officials: do him the favor of saving his life. 1386

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