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WASHINGTON, Sept. 14 (Xinhua) -- Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published Wednesday in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.The endometrium or uterine lining, is a source of adult stem cells. These cells generate uterine tissue each month as part of the menstrual cycle. Like other stem cells, however, they can divide to form other kinds of cells.Led by Yale Professor Hugh Taylor, the researchers bathed endometrial stem cells in cultures containing special nutrients and growth factors. Responding to these substances, the endometrial stem cells adopted the characteristics of beta cells in the pancreas that produce insulin. Over the course of a three- week incubation process, the endometrial stem cells took on the shape of beta cells and began to make proteins typically made by beta cells. Some of these cells also produced insulin.After a meal, the body breaks food down into components like the sugar glucose, which then circulates in the blood. In response, beta cells release insulin, which allows the body's cells to take in the circulating glucose. In this study, Taylor and his team exposed the mature stem cells to glucose and found that, like typical beta cells, the cultured cells responded by producing insulin. The team then injected diabetic mice with the mature, insulin-making stem cells. The mice had few working beta cells and very high levels of blood glucose.Mice that did not receive the stem cell therapy continued having high blood sugar levels, developed cataracts and were lethargic. In contrast, mice that received the cell therapy were active and did not develop cataracts, but the animals' blood sugar levels remained higher than normal.The Yale team's findings suggest that endometrial stem cells could be used to develop insulin-producing islet cells, which are found in the pancreas. These islet cells could then be used to advance the study of islet cell transplantation to treat people with diabetes.Taylor said in a statement that the next step in the research will be to verify how long this treatment remains effective.
WASHINGTON, May 30 (Xinhua) -- After nearly 12 days together in orbit, U.S. space shuttle Endeavour undocked from the International Space Station on Sunday night, NASA announced on Monday.According to NASA, the undocking took place at 11:55 p.m. EDT ( 0355 GMT Monday) as the spacecraft sailed 215 miles (346 km) above Bolivia.Pilot Greg Johnson, at the aft flight deck controls, flew Endeavour in a circle around the station at distances of about 450 to 650 feet. Crew members took still and video images of the station.The Space Shuttle Endeavour is seen as it departs the International Space Station after undocking in this image from NASA TV May 29, 2011.As Johnson was about to begin the flyaround, Commander Mark Kelly radioed mission control that he could see the two-billion-U. S.-dollar Alpha Magnetic Spectrometer (AMS) particle physics detector Endeavour had brought to orbit. "It's a new day for science on the space station," he said to mission control.The AMS will be left at the space station to scour the universe for clues about dark matter and antimatter. Endeavour is scheduled to land at the Kennedy Space Center at 2:35 a.m. (0635 GMT) on Wednesday.During their stay at the space station, the Endeavour crew conducted four spacewalks to complete construction of the U.S. side of the 100-billion-dollar outpost, a project of 16 nations that has been being assembled in orbit since 1998.They also brought up a logistics carrier with spare parts and performed some maintenance and installation work during the four spacewalks, the last to be carried out by an American shuttle crew.NASA plans to decommission Endeavour, its youngest shuttle with 25 voyages, and send it to a museum in Los Angeles for display.NASA's 30-year-old shuttle program is ending due to high operating costs. The Obama administration wants to spur private companies to get into the space taxi business, freeing NASA to focus on deep space exploration and new technology development.When the U.S. space shuttle program officially ends later this year, the Russian space program's Soyuz capsule will be the only method for transporting astronauts to and from the space station.
BERLIN, June 17 (Xinhua) -- German authority said on Friday first case of human spreading deadly E. coli is detected, as death toll increases to 39 worldwide.A woman working in a kitchen of a catering company was infected by E. coli from sprouts, though she didn't fall ill immediately, said Harald Kehlborn, a spokesman for the consumer protection ministry of German state Hesse.Then she spread E. coli unconsciously to another 20 people through the food she prepared, said Kehlborn.The woman later developed serious complication of hemolytic- uremic syndrome (HUS), which causes failure of kidney and nervous system.According to the data of the Robert Koch Institute, Germany's national disease control centre, the number of people who are infected has reached 3,408 in Germany and 798 people have fallen into HUS, while the infection speed is slowing down.
BERLIN, July 26 (Xinhua) -- German national disease control center said on Tuesday that the country's deadly E. coli outbreak has been over, as no new case reported in the last three weeks.The Robert Koch Institute (RKI) said the last case related to the E.coli outbreak was reported on July 4.As a three-week-period would cover the disease's incubation time, diagnosis time and the time for the transfer of a case, this virtually means an end of the outbreak."The largest EHEC outbreak is over in Germany," said RKI President Reinhard Burger. "I pay tribute to people who have joined in the great work, making investigation and looking after the patients."The RKI said Germany would keep watching the deadly EHEC O104: H4 intensively and asked people to pay attention to personal and food hygiene, as individual infection still cannot be ruled out.This round of outbreak has claimed 52 lives and affected more than 4,000 people since early May.The source of this disease was first believed to be cucumbers and tomatoes from Spain, and then was locked onto bean sprouts grown in a farm near Hamburg in the state Lower Saxony. Later European authorities said one batch of fenugreek seeds from Egypt was probably the source.
CAIRO, July 6 (Xinhua) -- Egypt's Central Administration of Agricultural Quarantine has denied again that the country's fenugreek seeds exported to Europe caused the E.coli infections which have claimed dozens of lives.The Egyptian authorities took and analyzed fenugreek seeds samples from the warehouse of the said Egyptian exporter and all results were negative by the strain, a statement posted on the official website of Egypt's Agricultural Ministry said on Wednesday."E.coli strain has not been reported in Egypt and no illness cases have been found," it added.If fenugreek seeds sprouts are suspected to be contaminated with E.coli pathogenic strain, it could be related to different handling processes, such as the re-packing or water used for sprouting, the statement said.The European Union (EU) on Tuesday agreed to ban the import of certain types of seeds from Egypt as Egyptian fenugreek seeds were reported to be linked with the outbreak of E.coli in Europe.The European Food Safety Authority (EFSA) published early Tuesday a report from its task force on the E.coli outbreaks in Germany and France, indicating that fenugreek seeds imported from Egypt is the most likely source of the outbreaks.The E.coli outbreak has killed over 50 people in Europe since it was first reported in late May.Russia's food safety watchdog Rospotrebnadzor has also banned the import of certain types of produce from Egypt over food safety concerns, a Russian official said on Wednesday.Egypt's Ministry of Agriculture refuted the claims of Egypt being the source of E.coli Friday.