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SAN DIEGO (KGTV) — UC San Diego researchers are testing a technology that's been in development for more than a decade to fight the coronavirus.In lab experiments, "nanosponges" covered in human lung cell membranes and immune cell membranes were found to attract and neutralize the SARS-CoV-2 virus in cell culture, according to a UCSD release. This caused the virus to lose about 90% of infectivity, or its ability to hijack cells and reproduce.The tiny sponges are designed to impersonate and protect healthy cells by soaking up harmful pathogens and toxins, according to Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering. RELATED: San Diego company's COVID-19 test gets emergency approvalFor example, the nanoparticle covered in membranes from cell types the virus is known to invade latch on to the virus. This prevent the virus from then entering an actual human cell."Traditionally, drug developers for infectious diseases dive deep on the details of the pathogen in order to find druggable targets. Our approach is different. We only need to know what the target cells are. And then we aim to protect the targets by creating biomimetic decoys," said Zhang.While Zhang has spent the last 10 years developing the technology, his lab turned to using the nano-particle to fight the coronavirus when the pandemic hit.RELATED: Scripps Research's antibodies study shows signs of success against coronavirusNow, the first data on the technology's ability to battle the virus is being released after testing by researchers at Boston University."Another interesting aspect of our approach is that even as SARS-CoV-2 mutates, as long as the virus can still invade the cells we are mimicking, our nanosponge approach should still work. I’m not sure this can be said for some of the vaccines and therapeutics that are currently being developed," said Zhang.UCSD researchers will test the nanosponges’ effectiveness in animal models in the next few months and are moving as fast as possible to eventually test the technology in humans. RELATED: Startup creates mobile COVID-19 testing clinic on wheelsNanosponges have a massive amount of testing ahead before they make it to human tests, Zhang said."I see potential for a preventive treatment, for a therapeutic that could be given early because once the nanosponges get in the lung, they can stay in the lung for some time," Zhang said. "If a virus comes, it could be blocked if there are nanosponges waiting for it."(Read more about the study and nanosponges here.) 2562

SAN DIEGO (KGTV)- A splash of color brings life back to Bay Park Elementary. Over the weekend, parents and volunteers joined together to give the school a facelift. The beautification project now has kids excited to come to school. “They were just blown away,” says Emily Auer. “Their face just lit up. They actually touched the walls.”Bay Park Elementary is approaching it’s the 80th anniversary. The school’s beautification team brought together almost 80 volunteers. The project started Friday night until late Sunday afternoon. Volunteers painted the walls and wooden backpack holders. Parents tell 10News one family donated a bunch of small desks with chairs that now sit in the halls. Behr gave the paint for the project. “Such a wonderful group of kids, so positive,” says parent Erica Krystek. “We really wanted that positivity reflected in the hallways.”The Bay Park Elementary Beautification Team plans to do more upgrades in the future. They hope to paint and add new carpet to the school’s auditorium. 1022

SAN DIEGO (KGTV) - Underused land owned by San Diego's Metropolitan Transit Service could help address the region's need for affordable housing — though not entirely.That's according to a new report by the think-tank Circulate San Diego, which suggests nearly 60 acres of MTS-owned land, including parking lots and structures, could better serve the community as new homes."Empty and underutilized parking lots are a stark and visible demonstration of public lands being underutilized. However, there are substantial real estate assets MTS already considers available for development which are not parking lots," Circulate San Diego's report recommended.RELATED COVERAGE: 679

SAN DIEGO (KGTV) — Two San Diego police officers responding to a call for a shoplifter in Ocean Beach ended up buying the suspect clothes and shoes instead of arresting him.It happened on Jan. 6 around 5 a.m. at the location on Sunset Cliffs Blvd. SDPD officers Christian Nimmons and Dominic Collins said employees at the drugstore reported that a homeless man had come in, stolen a sweatshirt and refused to leave.The store declined to press charges but wanted the man out of the store.But knowing it was very cold outside, and seeing the man also didn't have a shirt or socks and shoes, the officers decided to buy them for him."We looked at each other, asked how much the sweatshirt was going to cost, and had the same mutual decision of giving him the sweatshirt," said Collins.Both men told 10News it was simply the right thing to do and part of their job as officers to show compassion for those they come in contact with."I think he was more shocked that cops were doing something for him," Nimmons said. "We couldn't leave him like that. That was really it. It's what we joined to do. To help people."The man, only known to the officers as Daniel, reportedly put on the items and left. 1201

SAN DIEGO (KGTV) — Wasting away in "Margaritaville" will soon be an option much closer to home.The site of downtown's Solamar Hotel will be renovated to make way for the Margaritaville Hotel, set to open in 2021. The hotel will include 235 guest rooms and plenty of signature Margaritaville food and drink concepts for visitors.The renovation and full conversion of the hotel is expected to cost about million.RELATED: Margaritaville Island Resort coming to San Diego“We are excited to announce our second hotel in affiliation with Margaritaville in San Diego,” said Jon Bortz, CEO of Pebblebrook Hotel Trust. “The downtown location in San Diego’s famed Gaslamp Quarter will provide convention goers, leisure guests and corporate travelers a unique experience in very close proximity to the city’s dining, entertainment and retail venues ... The Gaslamp Quarter property will be a terrific complement to our Margaritaville Island Resort San Diego which was announced last year.”By 2021, Paradise Point Resort & Spa on Vacation Isle Park in Mission Bay will also see a similar transformation into the Margaritaville Island Beach Resort. The resort will feature 462 casita-style guest rooms, themed-food and drinks, and family-friendly amenities.The Solamar Hotel was purchased in 2018 by Pebblebrook Hotel Trust. The hotel is located on 6th Ave., near Gaslamp District dining and entertainment and blocks from Petco Park and the convention center — adding to its appeal for its new image.“We are thrilled to collaborate on our second hotel with Pebblebrook, a team that values quality design, creativity and engaging guest experiences,” said John Cohlan, CEO of Margaritaville. “The iconic Gaslamp District, with its dynamic nightlife, signature events and proximity to the home of the Padres, fits perfectly with the Margaritaville lifestyle." 1859

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