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SAN DIEGO (KGTV) -- Crews Thursday rescued a woman they say broke her leg while hiking above Blacks Beach.According to authorities, the incident happened around 2 p.m. in the Box Canyon area. Lifeguards say a woman in her 20s fell while hiking in the area and broke her leg.A helicopter could be seen lifting the woman from the canyon and taking her to a nearby hospital.Her condition is unknown at this time. 417

SAN DIEGO (KGTV) - Anyone touched by Alzheimer's knows how painful the disease is. "It's affected my family. It's affected most families. It's such a prevalent disease. As people get older, it becomes quite likely this will become an issue," said Paul Aisen, director of USC's Alzheimer's Therapeutic Research Clinic (ACTC).Aisen's team began their research in San Diego many years ago and teamed up with USC about four years ago. He's spent over 30 years trying to solve Alzheimer's mysteries and is leading the upcoming clinical trial.Aisen says the large-scale study is the culmination of decades of work from scientists worldwide."Our focus lately has been trying to alter the disease, prevent it, or significantly slow its progression. How should we do that? We think attacking amyloid early is the most promising approach," said Aisen. Researchers believe sticky amyloid deposits, which form on the brain later in life, start the Alzheimer's process. Aging, genetics, and lifestyle factors can all contribute to amyloid build-up.The worldwide clinical trial aims to target amyloid. A drug called BAN2401 will be delivered intravenously, designed to bind to the sticky amyloid. The binding neutralizes beta amyloid and helps "tag" it, so the immune system can recognize it and clear it from the brain. A previous phase 2 study showed that BAN2401 removes brain amyloid and possibly slows cognitive decline.They're seeking participants over 50 who are not yet showing symptoms of Alzheimer's but do have elevated amounts of amyloid on their brain. Researchers can determine that through a PET scan or spinal tap. "We think that the most promising approach of all is to take a vigorous attack on amyloid while the brain is still functioning normally. And we can see amyloid in people many years before they develop the symptoms of Alzheimer's."Investigators hope that by treating a patient with BAN2401 very early in the disease, before symptoms occur, it will significantly slow disease progression. "If we're successful, it will have a huge impact on human health," said Aisen. There will be 100 sites worldwide for the study, including major cities like San Diego and Los Angeles. Study participants will receive treatment for four years, given either the drug or a placebo. Results are expected in seven years, Aisen says. If you or a loved one wants to participate, learn more here.Screening will officially begin in May. 2438

SAN DIEGO (KGTV) - Cold temperatures and strong winds across San Diego County Monday prompted several weather advisories for the region. 144

SAN DIEGO (KGTV) - Crime Stoppers released photos Wednesday to find a man and woman suspected of two armed robberies in Otay Mesa and Pacific Beach. The first robbery happened the afternoon of Sunday, July 28 at Tepito Club, a clothing store at 2364 Roll Drive. Police said the pair selected merchandise and approached the clerk, then the woman pulled a gun and demanded cash. The couple took the money and drove off in a blue Toyota Corolla. One day later, police said the two suspects gathered items at the Chevron gas station at 1575 Garnet Ave., eventually demanding cash from the clerk. The man and woman walked away from the area with the money, police said. The suspects are both white, according to Crime Stoppers. The woman is 5’6”, thin, and was wearing a black tank top and grey leggings. The man has a medium build, and is about 30 years old with tattoos. Anyone with information is asked to call Crime Stoppers at 888-580-8477. Information leading to an arrest can result in a ,000 reward. 1012

SAN DIEGO (KGTV) — California has rejected San Diego County's request for a tier adjustment after the region was moved into the state's purple reopening tier.The county said that "San Diego’s increased cases are not due to the sectors impacted by moving into a more restrictive tier. County has interviewed cases to identify potential exposure settings and tracked community outbreaks."County health officials say businesses that will be impacted by purple tier restrictions saw the following breakdown of COVID-19 cases in October:Restaurant/bars: 7.4% of COVID-19 cases (715 of 9,646)Retail: 6.6% of COVID-19 cases (636 of 9,646)Places of worship: 1.9% of COVID-19 cases (184 of 9,646)K-12 schools: 1.7% of COVID-19 cases (165 of 9,646)Gyms: 0.4% of COVID-19 cases (39 of 9,646)In reference to October's data, the county said that, "outbreak data also show these sectors make up a small percentage of the cases overall ... Penalizing the impacted sectors for case increases is wrong, as these sectors continue to do the right things, while trying to weather the ongoing pandemic and the back and forth of re-openings."The county pointed to many local restaurants as an example of improving its mitigation efforts and investing in materials to make their settings safe for visitors, adding, "additionally, the closure of indoor restaurants, especially during the wintertime where outdoor dining is not optimal, will move individuals into homes and encourage gatherings, which is one of the high-risk areas for cases."Despite the request, the state decided on Sunday that the county will remain in the more restrictive purple tier.COUNTY'S EXPOSURE DATA (Oct. 25 - Nov. 7)According to county public health officials, between Oct. 25 and Nov. 7, there were a reported 5,576 COVID-19 cases.Of those cases, 3,833 cases were interviewed for contact tracing and 2,260 cases reported at least one of the potential exposure settings:Restaurant/bars: 389 casesBeach: 10 casesCasinos: 20 casesGroup gatherings: 159 casesGyms: 18 casesHair salon or barber: 97 casesPlaces of worship: 118 casesProtest: 0 casesRetail: 308 casesWork: 1,314 casesOther: 158 casesThe county says 1,573 of the 3,833 cases reported no potential exposure settings.Of all the cases between Oct. 25 and Nov. 7, the county says that people reported the possible exposure settings:Household exposure: 1,311 casesTravel-related exposure: 814 casesAny education-related exposure: 172 casesThrough Nov. 7, San Diego County has reported a total of 60,169 COVID-19 cases and 908 deaths from the virus. 2566