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WASHINGTON, Nov. 16 (Xinhua) -- Supervised exercise was shown to be more effective than stenting or medication for improved walking ability in patients with peripheral artery disease (PAD), according to a U.S. study reported Wednesday at the 2011 American Heart Association Scientific Sessions meeting.The research group reported that of 111 patients studied in the randomized trial, the most effective treatment proved to be supervised exercise based on the results of a treadmill test taken at baseline and again at six months. Patients who were in the supervised exercise group improved by a mean of 4.6 minutes in the treadmill test, while the group who received stents improved by a mean of 2.5 minutes. However, researchers found that self-reported quality of life measurements proved to be higher in the group that received stents, even though their ability to walk did not improve as greatly as the group that received supervised exercise rehabilitation.The findings were published in the November issue of the journal Circulation. The researchers believe that more studies are necessary, although supervised exercise may be an effective treatment recommended for PAD patients with claudication.PAD is a condition in which plaque builds up in the arteries and affects blood flow, especially to the legs. It is estimated that between 10 and 12 million people suffer from PAD in the United States. One symptom of PAD is known as claudication, a painful cramping of the leg muscles that limits the patient's ability to walk. It affects nearly 2 million people who suffer from PAD, and results in a sedentary lifestyle and poor quality of life.Current U.S. guidelines for the treatment of claudication include pharmacotherapy, supervised exercise rehabilitation and lower extremity revascularization using stents.

BEIJING, Oct. 13 (Xinhuanet) -- Tyrannosaurus rex dinosaur, the giant prehistoric predator, was even bigger and heavier than it was estimated previously, a new study found.The finding was contained in a study published Wednesday in the scientific journal PLoS ONE.Using three-dimension scanning and computer modeling, researchers analyzed five skeleton fossils of T. rex dinosaur, including "Sue", the largest and most complete T. rex specimen ever found.The analysis tipped the scale of "Sue" at 9 ton, some 30 percent more than it was expected."At their fastest, in their teenage years, they were putting on 11 pounds or 5 kilograms a day," said John Hutchinson of the Royal Veterinary College in London, who co-led the study.The larger body mass indicated the better agility and the stronger lower-leg muscles of the ancient monster, said the researcher."Sue" could have a top speed of about 10-25 miles per hour when it ran on the Great Plains of North America 67 million years ago, Hutchinson suggested.

ISLAMABAD, Nov. 14 (Xinhua) -- Pakistan ranks the seventh in the world in terms of diabetes prevalence rate and over 7.1 million people in the country are diabetes patients, reported local media on Monday.Quoting a report by the World International Diabetes Federation, a local English newspaper "The News" said that every year 89,000 people die of diabetes in Pakistan and the number of diabetes patients in the country could hit 11.5 million by the year 2025 if proper measures were not taken.This would make Pakistan the world's fifth largest country in terms of its number of diabetes patients 14 years later, warned the report.At a seminar organized Monday in Islamabad to observe the World Diabetes Day which falls on Nov. 14, Dr. Abdus Salam from Shifa International Hospital, a private-run hospital in the capital city, said that every ten seconds, two people are diagnosed with diabetes and one person dies of diabetes-related causes.The average age of diabetes patients in Pakistan is one of the lowest in the world, said the report. In a bid to raise public awareness about the harmful effects of diabetes, various diabetes camps, scientific sessions, seminars and walks were organized across the country on Monday to mark the World Diabetes Day.In a message delivered on Sunday, Pakistani Prime Minister Yusuf Raza Gilani said that the World Diabetes Day draws attention to the lethality of the disease and underscores the need of preventive measures at individual and collective levels."Diabetes is a killer which is taking the life of one person out of every 800," said the prime minister, adding that "this disease hits people of all age groups, rich and poor alike without any discrimination."

WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday revoked its approval of Avastin for treating the breast cancer after concluding that the drug has not been shown to be safe and effective for that use.Avastin will still remain on the market as an approved treatment for certain types of colon, lung, kidney and brain cancer."After reviewing the available studies it is clear that women who take Avastin for metastatic breast cancer risk potentially life-threatening side effects without proof that the use of Avastin will provide a benefit, in terms of delay in tumor growth, that would justify those risks," FDA Commissioner Margaret Hamburg said in a statement. "Nor is there evidence that use of Avastin will either help them live longer or improve their quality of life. "Avastin's risks include severe high blood pressure; bleeding and hemorrhaging; heart attack or heart failure; and the development of perforations in different parts of the body such as the nose, stomach, and intestines.Avastin was approved for metastatic breast cancer in February 2008 under the FDA's accelerated approval program, which allows a drug to be approved based on data that are not sufficiently complete to permit full approval. After the approval, the drug's sponsor, Genentech, completed two additional clinical trials and submitted the data from those studies to the FDA. These data showed only a small effect on tumor growth without evidence that patients lived any longer or had a better quality of life compared to taking standard chemotherapy alone -- not enough to outweigh the risk of taking the drug.FDA's Center for Drug Evaluation and Research, which is responsible for the approval of this drug, ultimately concluded that the results of these additional studies did not justify continued approval and notified Genentech it was proposing to withdraw approval of the indication.Genentech did not agree with the Center's evaluation of the data and, following the procedures set out in FDA regulations, requested a hearing on the Center's withdrawal proposal, with a decision to be made by the Commissioner. That two-day hearing, which took place June 28-29, included recommendations from the FDA 's Oncologic Drugs Advisory Committee, voting 6-0 in favor of withdrawing approval of Avastin's breast cancer indication.

BALI, Indonesia, Nov. 19 (Xinhua) -- Leaders of China, Japan and South Korea met here Saturday to exchange views on trilateral cooperation and regional and international issues of common concern.Chinese Premier Wen Jiabao, Japanese Prime Minister Yoshihiko Noda and South Korean President Lee Myung-bak were meeting on the occasion of a series of meetings for East and Southeast Asian leaders in this Indonesian resort city on Friday and Saturday.Speaking at the meeting, Wen said the cooperation between the three nations currently had good momentum, which was not only in line with the interests of the three sides but also contributed to the stability and development of the Asia and the world.Chinese Premier Wen Jiabao (L), Japanese Prime Minister Yoshihiko Noda (C) and Republic of Korea (ROK) President Lee Myung-Bak pose for photos during the Trilateral Summit Meeting for leaders of the three nations in Bali, Indonesia, Nov. 19, 2011.As the coordinator of next year's China-Japan-South Korea cooperation, China would like to further enhance high-level exchanges, policy coordination and strategic trust between the three countries, providing political impetus and promoting more advancement in trilateral cooperation, Wen said.He said next year marked the 40th anniversary of the normalization of diplomatic relations between China and Japan, and the 20th anniversary of the establishment of diplomatic relations between China and South Korea.In the meeting, Wen proposed the joint research into a free trade area between the three countries be completed this year, and negotiations start in 2012.Wen also suggested enhancing trilateral cooperation in the fields of transportation, finance and environmental protection, among many others.Also speaking at the meeting, the Japanese prime minister and the South Korean president said the cooperation between the three nations had seen remarkable achievement and its prospects were promising.The three sides should continue to deepen their exchanges and cooperation in various fields including economy and trade, finance, investment, disaster relief, culture, education and tourism, and strengthen the coordination in regional and international issues to promote common development, according to them.During the meeting, the three leaders also exchanged views on other regional and international issues of common concern.

来源：资阳报