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WASHINGTON, July 15 (Xinhua) -- Researchers at Mount Sinai School of Medicine have found that grape seed polyphenols -- a natural antioxidant -- may help prevent the development or delay the progression of Alzheimer's disease.The research, led by Giulio Pasinetti, was published online Friday in the Journal of Alzheimer's Disease, which causes brain changes that gradually get worse.This is the first study to evaluate the ability of grape- derived polyphenols to prevent the generation of a specific form of amyloid (A) peptide, a substance in the brain long known to cause the neurotoxicity associated with Alzheimer's disease.In partnership with a team at the University of Minnesota, Pasinetti and collaborators administered grape seed polyphenolic extracts to mice genetically determined to develop memory deficits and A neurotoxins similar to those found in Alzheimer's disease. They found that the brain content of the A*56, a specific form of A previously implicated in the promotion of Alzheimer's disease memory loss, was substantially reduced after treatment.Previous studies suggest that increased consumption of grape- derived polyphenols, whose content, for example, is very high in red wine, may protect against cognitive decline in Alzheimer's. This new finding corroborates those theories."Since naturally occurring polyphenols are also generally commercially available as nutritional supplements and have negligible adverse events even after prolonged periods of treatment, this new finding holds significant promise as a preventive method or treatment, and is being tested in translational studies in Alzheimer's disease patients," said Pasinetti.In Alzheimer's disease, brain cells degenerate and die, causing a steady decline in memory and mental function.

WUHAN, Aug. 6 (Xinhua) -- A Chinese man nearing 80 years old was recently diagnosed with HIV and doctors say he probably caught the virus through having "frequent unprotected sex."The case is the latest to support the opinions of experts who believe the virus is spreading fast among older Chinese men who have been largely neglected in the country's anti-AIDS campaigns.The latest diagnosed man, whose identity has been concealed for privacy reasons, was admitted to Zhongnan Hospital in central Chinese city of Wuhan with a lingering fever. He was later found to be HIV positive, doctors at the hospital said Friday.The man was widowed in his old age, has no record of blood transfusions, but had an "active unprotected sexual life," they said.Gao Shicheng, a HIV specialist in Zhongnan Hospital, said that HIV/AIDS has started to infect middle-aged and elderly Chinese men who have little or no AIDS prevention knowledge.Gao said this year alone he had diagnosed two senior men with HIV. Both contracted the virus through unprotected sex outside marriage.A recent survey conducted by the Chinese Center for Disease Control and Prevention (China CDC) shows that among the new HIV infections, the percentage of people aged 50 or above with it grew from 7.8 to 14.9 percent. Most of them were male and were found to have contracted the virus through sexual intercourse.Experts say the spread of HIV/AIDS has picked up among older Chinese men in recent years because China's senior citizens have become healthier, more open-minded about sex, and increasingly bored after retirement.They called for anti-AIDS campaigns, which usually target young people with a focus on gays, sex workers, and rural migrants, to also cover seniors in a bid to raise the awareness of HIV/AIDS prevention knowledge.China is fighting a hard battle to contain the spread of HIV/AIDS. According to a UNAIDS estimate, the country had about 740,000 people living with HIV by the end of 2009. Among them, 105,000 were estimated to have AIDS.By the end of August 2010, the cumulative total of reported HIV positives in China was 361,599, with 65,104 recorded deaths.Sex, other than blood transmission or mother-to-child transmission, has become the main channel for the spread of HIV in China.

SHENZHEN, June 4 (Xinhua) -- Chinese scientists who have fully sequenced the genome of the new E. Coli spreading through Europe said Saturday they found genes in the bacteria that gave it resistance to eight classes of antibiotics.Researchers with the Beijing Genomics Institute, the world's largest DNA sequencing center, have found genes in the newly identified 0104 strain of E. Coli bacteria that made it resistant to major classes of antibiotics including sulfonamide, cephalothin, penicillin and streptomycin.This helped explain why doctors in Europe had difficulties in fighting the bug that has killed 18 people and sickened nearly 2,000, BGI's major research arm in Shenzhen said on its website Saturday.This would help doctors choose right medicines for the treatment, it said.The researchers are developing a diagnostic kit which will be used to detect the bacteria and prevent the epidemic from spreading further.The Chinese researchers obtained DNA samples of the bacteria from collaborating scientists in Germany and fully sequenced its genome in three days this week.They announced on Thursday the E. Coli spreading through Europe was "a new strain of bacteria that is highly infectious and toxic".The 0104 strain of E. Coli was not previously involved in any E. Coli outbreaks. However, it has 93 percent sequence similarity with the EAEC 55989 E. Coli strain which was isolated in the Central African Republic and known to cause seriously diarrhea, BGI said.The source of the outbreak is unknown, but scientists say it is highly likely to have originated in contaminated vegetables or salad in Germany.

CHANGSHA, July 17 (Xinhua) -- Chinese State Councilor Liu Yandong has called for more communications in language and culture among the people in China and foreign countries.Liu made the remarks during a meeting with the contestants of the 10th "Chinese Bridge" competition, an international Chinese proficiency competition for foreign college students, which opened Saturday in Changsha, capital of central Hunan Province.The "Chinese Bridge" competition has attracted over 100,000 college students from more than 70 countries over the past ten years, and contestants have improved their Chinese language, experienced the Chinese culture and established deep friendship with others during the competition, Liu said.She said that language is a tool for cultural communications, and linguistic learning and exchanges can promote the mankind's civilization and progress in a broader reach."The Chinese government always encourages the public, especially the youths, to learn foreign languages, and through the learning, they are enlightened on the diversified cultures around the world," she said."This also helps promote the good-will exchanges and cooperation among the Chinese and foreign peoples," she added.Liu said the Chinese government is also making efforts to meet the needs of foreign people to learn the Chinese language. She called on foreign young students to improve their Chinese proficiency and to use the Chinese language as a bridge to fell a real China in a comprehensive way.She expressed her hope that the foreign students will spread the good will and sincerity of the Chinese people to other parts of the world, in order to promote the joint efforts for the peace and prosperity of the world.

WASHINGTON, Aug. 18 (Xinhua) -- Black scientists were significantly less likely than their white counterparts to receive research funding from the National Institutes of Health (NIH), according to an analysis of data from 2000 to 2006.University of Kansas Professor of Economics Donna Ginther was the lead author on the study commissioned by the NIH, which will appear Friday in journal Science.The researchers found a 10 percentage point gap in research funding -- even after taking into consideration demographics, education and training, employer characteristics, NIH experience and research productivity. For example, for every 100 grants submitted to NIH, 30 grants from white applicants were funded, compared to 20 grants for black applicants.Applications for NIH funding go through peer review that considers the significance, innovation and approach of grant applications, the investigator(s) and the research environment. About half of the applications are determined to be worth scoring. Among those scored, budgets and NIH Institutes priorities determine which applications are funded. Priorities can vary by year and by Institute.The study found that applications from black researchers were less likely to be scored and on average had worse scores. After controlling for the score of the grant, there were no race or ethnicity differences in funding.Applicants self-identify race, ethnicity and gender, but that information is not available during the peer review. However, biographical facts that are included in the review materials can provide clues to the identity of the applicants.The research suggests it is possible that cumulative advantage may explain the funding differences."Small differences in access to research resources and mentoring during training or at the beginning of a career may accumulate to become large between-group differences," the paper says.Additionally, the paper suggests further research is needed to determine why black researchers are less likely to be funded.NIH Director Francis Collins and Principal Deputy Director Lawrence Tabak call the findings unacceptable and commit to immediate action by the NIH."NIH commissioned this study because we want to learn more about the challenges facing the scientific community and address them head on. The results of this study are disturbing and disheartening, and we are committed to taking action," said Collins in an accompanying commentary. "The strength of the U.S. scientific enterprise depends upon our ability to recruit and retain the brightest minds, regardless of race or ethnicity. This study shows that we still have a long way to go."NIH initiated the study in 2008 to determine if researchers of different races and ethnicities with similar research records and affiliations had similar likelihoods of being awarded a new NIH research project grant.