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SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459

SAN DIEGO (KGTV) - It's a weekend for food, fun, and a funky-smelling flower.Fleet Science Center is bringing the magic of "Star Wars" to our galaxy with a pre-party and private screening of "Solo: A Star Wars Story."Bolt Brewery is hosting a celebration for the local non-profit Traveling Stories with performances by "One Tree Hill" star Tyler Hilton and former American Idol contestant Lindsey Carrier in La Mesa, complete with food and drinks, and activities for kids.Don't see anything interesting? Check our 10News event calendar for even more local happenings!Catfishing season is back in Lakeside, with Lake Jennings being stocked with 2,000 pounds of catfish for Memorial Day weekend.Vista's famed Strawberry Festival also returns, with more than 400 vendors, carnival rides, and, of course, lots of strawberries.If you're willing to put up with the scent, a "corpse flower" will be in bloom at the San Diego Botanical Gardens this weekend as well. The name is enough warning of what you'll smell.THURSDAYFleet Night of ScienceWhere: Fleet Science Center; Cost: .49Celebrate the opening of the new Star Wars flick, "Solo: A Star Wars Story" with a pre-party at the Sandbox followed by a private screening! Jump into themed activities, meet the local 501st Legion Stormtroopers, and explore the "Star Wars" universe with Dr. Lisa Will and Dr. Shane Haggard and comedian Robert Timothy. Family Fun FestWhere: Bolt Brewing; Cost: - Local nonprofit Traveling Stories is celebrating their 8th year with a family fun fest, featuring a silent auction, food and drinks, activities for kids, and live performances from Tyler Hilton, of "One Tree Hill," and Lindsey Carrier, a former American Idol contestant. 1765

SAN DIEGO (KGTV) - It’s getting harder and harder to buy a home in San Diego. But according to Veterans United Home Loans, VA loans in California are surging, and they’re up 15 percent this year in San Diego.Navy veteran Robert Streets and his wife Corrie are part of that surge."There was a large cabinet that came out here, and we knocked that down," says Streets in his recently remodeled kitchen.The Streets are proud to show off their new home. After renting for years, they're first time home buyers as of July, purchasing a condo in the heart of North Park.RELATED: Making It in San Diego: Sailor gets proactive to find housing"I remember the first feeling that I got when we got our keys, and we got into the house, and I was like, 'Wow,'" adds Streets with a sense of relief. "I own this, and I can do whatever I want. I don't have to ask somebody if I can put a hole in the wall or hang a picture."While Millennials are struggling to buy in San Diego, Millennial Veterans are surging in home purchases, up 61 percent according to Veterans United with an average purchase price of almost 0,000. And for the Streets, it was made possible using a VA Loan. "They got all the paperwork together, all the legal stuff sorted out, and they actually made the condo VA qualified so that we were able to use our VA loan. Which wouldn't have ever been in here if it wasn't for that," says Corrie Streets.The Streets are far from alone. VA purchase loans in California are up 66 percent from 2013 to 2018."This is either the most financially advantageous path or, in some cases, it’s the only feasible path to homeownership," says Chris Birk.RELATED: Making it in San Diego: Millennials outpace Generation X in both total debt and long-term savingsBirk is Director of Education at Veterans United Home Loans. He says in some cases veterans and service members, if they qualify, can get a VA loan for no money down. The average 30-year rate for June was 4.2 percent, better than most conventional loans. "They don't have to build pristine credit,” adds “Birk. “And one of the biggest benefits is that so many veterans and service members aren't weighed down by student loan debt."And then there are vets like Wendell Stone. He and his wife Tessie rented for 30 years. That's when their daughter-in-law Aurora Perez, a realtor at Century 21, helped them understand they could qualify for a VA loan."They were able to purchase a home with my help in the Temecula area,” says Perez. "And then they were able to purchase another home in Oceanside and turn that into an investment property."Currently, there is a 0,000 cap on VA loans in San Diego County. But Perez says the laws are about to change and next year if a veteran or service member can qualify, there will be no cap for VA loans.Are you a veteran or service member in the market for a new home? Here’s your complete guide to the VA Home Loan. 2911

esslie Severns first attended in 2017, when she had just gotten out of the military.Severns said when she walked into the room that day, she began to cry. “This makes you feel so good, that people care about you, that they go this far to donate all their clothes, and it just makes you feel empowered and ready to go back out and face this new life that you’re about to experience,” she said.Operation Dress Code also offers free make-up lessons, professional headshots and career workshops.San Diego's Courage to Call, CalVet and dozens of local businesses and organizations work together to host the annual event. 1107

SAN DIEGO (KGTV) — Looking for a discount on family fun this summer in San Diego?Boomers! is offering more than half-off the price for 2020 season passes, which can be used in 2019 through Dec. 31, 2020. Online, individual season passes are available for , while passes purchased in-park are . Passes regularly retail for 0.If purchasing three or more, the discount drops to a season pass.RELATED: SeaWorld San Diego offers end-of-summer salePass holders then get unlimited rides on attractions like miniature golf, go-karts, bumper boats, a rock climbing wall, 25 pitches in the batting cages, for the arcade, and more.The season pass also locks guests in for special events for Halloween, New Year's Eve, and Easter, in addition to several discounts around the park and on friend admission.The discounts bring season passes in line with all-day attraction passes for a single day, which range between -. Single attraction pricing also ranges between and per ride on mini-golf, go-karts, and bumper boats.The 2020 pass discount is a limited-time deal and only available locally at San Diego and El Cajon Boomers! locations. 1162