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SAN DIEGO (KGTV) -- Support for the Black Lives Matter movement is now visible on a downtown San Diego street.Over the weekend, various Black Lives Matter banners were put up on Broadway, between Third Avenue and Kettner Boulevard.The banners showcase the work of San Diego-based artist Anthony Tyson, and they display the message that Black lives of every age, gender, preference, past, and future matter.“You know, not that many people of my color, of my ethnicity is around this area. So, my people can come down and see it, and then also you have people that are used to this area seeing something different. And it gets them to ask the question of ‘what is this?’ and that's all you really need at the end of the day,” Tyson told ABC 10News.Tyson collaborated with the nonprofit Downtown San Diego Partnership for the project.“The Downtown Partnership believes strongly in its duty to ensure organizational efforts are promoting equality and addressing systemic injustice and racial discrimination wherever they exist. In addition to commitments made within the organization, the Downtown Partnership is working to foster a greater sense of cultural vibrancy through placemaking and special projects. Particularly when those efforts can highlight historically disadvantaged cultural institutions and artists,” the organization said in a news release. 1363

SAN DIEGO (KGTV) — The National Institutes of Health highlighted research Tuesday out of UC San Diego that could unlock a new way to treat COVID-19.The research reveals new insight into how the coronavirus hijacks cells, and how doctors might be able to set traps or decoys to combat the virus. The findings were published in the journal Cell last month.“It does open up another avenue for a potential treatment,” said UC San Diego distinguished professor Dr. Jeffrey Esko. “It’s not a cure. It would be something that would tamp down infection potentially.”Since January, scientists around the world have understood that SARS-Co-V2, the official name of the new coronavirus, enters cells by latching onto a specific receptor on the cell’s surface, called ACE2.The UCSD team, led by Dr. Esko and visiting scholar Dr. Thomas Clausen, discovered that this entry mechanism is actually a two-step process, and the virus must also attach to a long chain of sugars called heparan sulfate.“We’ve shown this is fundamental to the infectious mechanism, so it needs to be part of every study from now on,” said Clausen.All cells are coated with a complex layer of sugars, or carbohydrates, called glycans. Heparan sulfate is one type of glycan that is known to play a key role in the infection process in several viruses, including herpes and other coronaviruses.It’s a complicated process to picture so the researchers offer an analogy: imagine a bird, soaring over trees, hunting a worm on the forest floor. The bird is the coronavirus and the trees are the thick layer of glycans that coat the surface of the cell.To reach the worm, which in this case is the receptor ACE2, the bird must navigate its way through the trees, specifically through heparan sulfate.The UCSD found that by removing the heparan sulfate trees with an enzyme, they were able to prevent the virus from infecting cells. In laboratory testing, they also found a second technique worked to foil the virus: introducing more trees as bait.The team found that heparin, an FDA-approved drug that is similar in structure to heparan sulfate, successfully acted as decoy. Heparin is a widely used drug designed to treat blood clots. Since blood clots and strokes are common complications with COVID-19, many doctors already administer heparin to patients.The UCSD team demonstrated that the two approaches can block infection in lab-grown cells about 80 to 90 percent of the time.“Certainly in the laboratory you can demonstrate that it works, but to deploy it and use it as a therapeutic has not been demonstrated,” Esko said.The NIH noted that more studies are planned to explore whether heparin, heparan sulfate, or drugs that target heparan sulfate might yield a viable COVID-19 treatment.Dr. Esko said he’s already been in talks with companies that plan to use their study as a rationale for a clinical trial.“It is very humbling when you realize we’re working on a pandemic right now, and maybe what we’ve done can contribute to a treatment for the disease,” he said. 3038

SAN DIEGO (KGTV) — The holiday season is underway in San Diego, as locals prepare to jump into December this weekend.Outdoor ice skating can be found at Viejas Casino and Resort's massive outdoor ice rink, and Carlsbad welcomes the "big man" to town to help light their Christmas tree!Legoland also jumps into the season with Holidays at Legoland and several street festivals and art shows give you the chance to get a jump on holiday shopping for friends, family, and pets!Not interested in anything here? Check out the 10News?community events calendar for a look at even more things to do!But Thanksgiving is first on the list. The 72nd annual Mother Goose Parade in El Cajon will ring in the season for being together with family and friends, as local gather to watch floats, bands, and Santa glide through town.Here's a look at this weekend's big events:THURSDAYOutdoor ice skating at ViejasWhere: Viejas Casino & Resort; Cost: - (Runs Thursday - Sunday) Holiday lights and entertainment have arrived at Viejas! Get into the winter spirit with ice skating at one of the biggest Southern California rinks around. A 90-minute session for kids will run while adults and teens can skate for . Art of the Holiday?ShowWhere: Fallbrook Art Center; Cost: Free(Runs Thursday - Saturday) Explore handmade crafts and jewelry by talented artists at Fallbrook Art Center's free Art of the Holiday Show. Wearable art, glass and ceramics, ornaments, and more can be found as a unique and creative gift this season! FRIDAYTree Lighting & Santa ArrivalWhere: Carlsbad Premium Outlets; Cost: FreeWelcome in the holiday season with Santa as he helps light Carlsbad's outlet Christmas tree. Enjoy holiday performances by Samantha Robertson, Singers Company, and the Carlsbad Company Theatre as well, and get a start on your holiday shopping. Del Mar Antique Show & SaleWhere: Del Mar Fairgrounds; Cost: Free(Runs Friday - Sunday) Del Mar Fairgrounds will be packed with vintage collectibles and antiques spanning glass, pottery, jewelry, art, and much more at the Antique Show & Sale. Have your own treasure? Appraisal team members can take a look and see if you've struck vintage gold! SATURDAYPadres Pedal the CauseWhere: Petco Park; Cost: - 5Pedal the Cause rallies the San Diego community to raise awareness and funding for cancer research in San Diego. The challenge includes four cycling courses, spin classes, or a 5K run/walk ending in centerfield inside Petco Park! You choose! Holidays at LegolandWhere: Legoland California; Cost: (Runs Saturday - Sunday) Holiday magic kicks off at Legoland, where a 30-foot high Lego Christmas tree will play centerpiece to a park full of holiday cheer. Make sure to visit Lego Santa and a cast of characters at the new Holiday Village! 10th Annual Doggie Street FestivalWhere: Liberty Station; Cost: FreeLiberty Station's Doggies Street Festival brings together live entertainment, auctions, and, of course, everything cats and dogs for pet owners and those looking to adopt a furry friend. Visit with rescue societies and get tips from vets and pet services, and bring your own doggo to enjoy the festival too!  SUNDAY72nd annual Mother Goose ParadeWhere: El Cajon; Cost: FreeEl Cajon's Mother Goose parade is billed as the largest parade in San Diego County! Celebrate Thanksgiving as thousands line the streets to watch Santa, marching bands, and more as the parade begins on Main St. at El Cajon Blvd. marching toward First St. 28th annual Encinitas Holiday Street FairWhere: Downtown Encinitas; Cost: FreeHead out for free fun in Encinitas, including two stages of live entertainment, delicious food, children's rides and games, and more during the Encinitas Holiday Street Fair. Vendors will also be out giving guests the chance to get some holiday shopping done, offering handmade crafts, art, and more! Taco TKOWhere: Liberty Station; Cost: Help discover San Diego's best taco during an all-you-can-eat taco showdown at Liberty Station! Taco TKO pits local restaurants against each other for the title of "San Diego's Most Awesome Taco," as part of the San Diego Bay Wine + Food Festival. 4299

SAN DIEGO (KGTV) — The California Coastal Commission Wednesday signed off on a demonstration of the lighting project that would illuminate pillars of the Coronado Bay Bridge.The project will include installing lights along four pillars of the bridge, which will be tested during one week in June. Following the test, an environmental impact study will be conducted.The tests are part of a larger effort for a proposed artist-designed lighting project that would span 30 pillars of the 2.12-mile bridge. The Port of San Diego is trying to raise between - million to complete the project by 2022.At completion, the Port hopes to have a finished lighting display by artist Peter Fink, meant to serve as a gateway to the region and in a variety of scenarios using its programmable LED displays. Several sections of the bridge were illuminated last April during a study of the project. 894

SAN DIEGO (KGTV) -- The California Highway Patrol is investigating following a crash involving a military Humvee Thursday night.The crash happened on eastbound Interstate 8 just west of Dunbar Lane. Five vehicles were involved in the crash.As a result of the incident, traffic was backed up on the interstate for miles. The cause of the collision is unknown at this time and there are no reports of injuries.Sky10 was over the scene of the crash. Watch video in the player below: 487