山东得了痛风怎样治疗好(济南被溶解的痛风石真假) (今日更新中)

WASHINGTON, April 11 (Xinhua) -- In the first clinical trial of gene therapy for treatment of intractable pain, U.S. researchers from the University of Michigan's Department of Neurology observed that the treatment appears to be able to provide substantial pain relief.In a study published online in the Annals of Neurology and seen on Monday, the researchers showed that the novel agent NP2 is safe and well-tolerated. In addition, measures of pain in the treated patients suggested that NP2 may provide a substantial analgesic effect.NP2 is a gene transfer vector that expresses the naturally- occurring opioid peptide enkephalin. In preclinical work in animals, David Fink, chair of the Department of Neurology, and his coworkers had demonstrated that injection of NP2 into the skin reduces pain in models of pain caused by nerve damage, inflammation or cancer.In the clinical trial, 10 patients with unrelenting pain caused by cancer were injected with the gene transfer agent in the area of skin related to the location of pain."The concept underlying this therapeutic approach is that injection of NP2 into the skin results in uptake into the nervous system and the production and release of a pain-relieving chemical in a controlled site in the pain pathway," says Fink. "In the study, patients who received the low dose of vector showed little reduction in pain; patients receiving the higher doses showed a greater than 80 percent reduction in pain over the course of four weeks following treatment."Fink's laboratory has been working on the use of modified herpes simplex virus-based vectors that are taken up by sensory nerves following skin injection to develop therapies for diseases of the nervous system for more than 20 years. Patents related to this technology have been exclusively licensed by Diamyd Medical, a publicly-traded Swedish biotechnology company that sponsored the trial, and the human-grade vector NP2 was produced by Diamyd, Inc, the U.S. subsidiary of Diamyd Medical.A phase 2 trial to compare NP2 to a placebo control has already been initiated under sponsorship from Diamyd.

WASHINGTON, Feb. 7 (Xinhua) -- The U.S. International Trade Commission (USITC) determined Monday that imports of drill pipe and drill collars from China threatened the U.S. industry with material injury.As a result of the USITC's affirmative threat determinations, the U.S. Commerce Department will issue anti-dumping and countervailing duty orders on imports of these products from China.On January 4, the U.S. Commerce Department announced its affirmative final determinations in the anti-dumping duty and countervailing duty investigations on imports of drill pipe from China. The department determined that Chinese producers and exporters had sold drill pipe in the United States at margins ranging between 0.00 and 69.32 percent, while they have received countervailable subsidies of 18.18 percent ad valorem.In the anti-dumping investigation, mandatory respondent China's DP Master Manufacturing Co., Ltd. and Jiangyin Liangda Drill Pipe Co., Ltd. received a dumping rate of 69.32 percent. Baoshan Iron and Steel Co., Ltd. as well as Shanxi Yida Special Steel Imp. and Exp. Co., Ltd. each received a dumping rate of 0.00 percent, according to the department.The USITC did not specify the combined value of imported drill pipe and drill collars from China in the statement. A determination will be considered as affirmative if there is a 3-3 voting result within the USITC Commissioners.Drill pipe and drill collars are hollow drill string components used in drilling rigs, particularly those intended to extract oil and gas, to transmit power and conduct lubricant during the drilling process.

LOS ANGELES, April 2 (Xinhua) -- People taking antidepressants may be more likely to develop thicker arteries which may raise the risk of heart disease and stroke, a new study suggests.Depression can heighten the risk for heart disease, but the effect of antidepressant use is separate and independent from depression itself, according to the study make public by the American Association for the Advancement of Science (AAAS) on Saturday.The data suggest that antidepressants may combine with depression for a negative effect on blood vessels, said study first author Amit Shah, MD, a cardiology fellow at Emory University School of Medicine.Study findings will be presented on April 5 at the American College of Cardiology meeting in New Orleans, according to the AAAS.The study included 513 middle-aged male twins who both served in the U.S. military during the Vietnam War. Twins are genetically the same but may be different when it comes to other risk factors such as diet, smoking and exercise, so studying them is a good way to distill out the effects of genetics.Researchers measured carotid intima-media thickness - the thickness of the lining of the main arteries in the neck -- by ultrasound. Among the 59 pairs of twins where only one brother took antidepressants, the one taking the drugs tended to have higher carotid intima-media thickness (IMT), even when standard heart disease risk factors were taken into account.The effect was seen both in twins with or without a previous heart attack or stroke. A higher level of depressive symptoms was associated with higher IMT only in those taking antidepressants."One of the strongest and best-studied factors that thickens someone's arteries is age, and that happens at around 10 microns per year," Shah said. "In our study, users of antidepressants see an average 40 micron increase in IMT, so their carotid arteries are in effect four years older."Antidepressants' effects on blood vessels may come from changes in serotonin, a chemical that helps some brain cells communicate but also functions outside the brain, Shah said."I think we have to keep an open mind about the effects of antidepressants on neurochemicals like serotonin in places outside the brain, such as the vasculature. The body often compensates over time for drugs' immediate effects," Shah said. " Antidepressants have a clinical benefit that has been established, so nobody taking these medications should stop based only on these results. This isn 't the kind of study where we can know cause and effect, let alone mechanism, and we need to see whether this holds up in other population groups."

CHICAGO, Jan. 20 (Xinhua) -- Chinese President Hu Jintao arrived here on Thursday afternoon from Washington, after meetings with U.S. President Barack Obama on major bilateral and world issues.During their talks Wednesday, the two leaders agreed to build a China-U.S. cooperative partnership based on mutual respect and mutual benefit.In Chicago, Hu will meet local officials and visit a high school, Chinese officials said.Chinese President Hu Jintao (R front) meets with Mayor of Chicago Richard Daley(L front) in Chicago, the United States, Jan. 20, 2011. Hu arrived in Washington Tuesday for a four-day visit to the United States. The trip, his second as head of state, is aimed at enhancing the positive, cooperative and comprehensive relationship between China and the United States.The Chinese president visited the United States in April 2006.

CANBERRA, May 10 (Xinhua) -- Technology may have a harmful effect on children's development and creativity, Australia's report found on Tuesday.The Pilot Pen Australia Creativity Report found that children could be depending too much on technology such as computers.Written by psychologist Kimberley O'Brien, the report suggested that students are becoming scared of handwritten tasks as there is no spelling or grammar check tool to pick up their mistakes as they go along."Children who develop this kind of dependency on computer software are less likely to write using a pen and paper given that they will feel a vulnerability to failure," the report said.It said using software that immediately tells children to correct errors like spelling and grammar could disrupts their thought patterns and stunts their ideas, and children who hand write are able to produce almost twice as many ideas as those using computer technology to write a creative story.The report studied 300 Year five and six children, and found handwritten essays were completed significantly faster and contained a higher standard of sentence structure, grammar, punctuation, cohesion, ideas development and organization than those completed using keyboards.A further study found students in Years two, four and six produced up to twice as many ideas writing on pen and paper as those on computers.O'Brien said the results were due to computers putting extra pressure on writers to edit as they go rather than get their ideas down first and edit minor mistakes later.O'Brien said children were most likely to develop their handwriting skills between the ages of eight and 10, and she urged all teachers and parents to ensure their children met community standards for legible handwriting.However, she said that computers are a good support tool, and they should not replace handwriting entirely.

来源：资阳报