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BEIJING, Aug. 22 (Xinhuanet) -- Researchers have discovered how a human egg captures an incoming sperm for fertilization, paving the way to help couples suffering from infertility, according to media reports on Monday.An international team of researchers found that a sugar chain known as the sialyl-lewis-x sequence (SLeX) makes the outer coat of the egg “sticky,” which has proven to be helpful in binding the egg and the sperm.As a result, this observation has filled in a huge gap in the understanding of fertility and provides hope for ultimately helping couples who currently cannot conceive.Scientists and doctors know that a sperm identifies an egg when proteins on the head of the sperm match and bind to a series of specific sugars in the egg’s outer coating. With a successful match of proteins, the outside surfaces of the sperm and egg then bind together before merging, which is then followed by delivery of sperm’s DNA into egg.To identify this molecules, the researchers used ultra-sensitive mass-spectrometric imaging technology to observe and identify which molecules are most likely to be key in the binding process.They experimented with a range of synthesised sugars in the laboratory and found that it is SLeX that specifically binds sperm to an egg.According to the World Health Organisation, infertility affects about 15 percent of reproductive-aged couples around the world and almost one in every seven couples in Britain has problems conceiving a child for various reasons.

HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.

RAMALLAH, Aug. 26 (Xinhua) -- China's special envoy to the Middle East, Wu Sike, said here Friday that his country fully supports the Palestinians' right to establish an independent state in a balanced manner and through peace talks."China supports the Palestinian people and their cause. We also support the Palestinians to get the United Nations recognition of a Palestinian state on the lands occupied in 1967 with Jerusalem as capital," he told Xinhua in Ramallah.The envoy said peace talks with Israel are the best way to reach a settlement, adding that gaining UN recognition is not an alternative to peace negotiations.China supports a two-state solution -- Israel and an independent Palestinian state living side-by-side in peace and security, he said, noting that he believes the current developments in the Middle East have a positive impact on the Palestinian cause."The Middle East witnesses many changes. People have many chances to participate in political life. The Palestinian cause is a main issue that attracts the attention of the Arab people," he said."The recent meeting of the Arab League Peace Initiative Follow- Up Committee in Qatar assures the Arabs' support to the Palestinians' bid for full UN membership," he said. "This will help the Palestinians gain more international support."The Palestinians say they will approach the UN in September to get full membership of the world body as peace talks with Israel have long been deadlocked, a move disapproved by Israel and the United States.Wu expressed his appreciation of the reconciliation deal signed between Palestinian National Authority President Mahmoud Abbas' Fatah party and Hamas movements in Cairo in May."This move will help the Palestinians to have more countries on their side," he said.Wu said his Middle East tour was taking place at an important moment as the region is witnessing crucial changes, stressing that China respects the choices of the peoples."The Arab peoples are able to make their own decisions toward development," said the envoy.He also said the ties between China and the Arab countries are based on strong foundations, regardless of the changes taking place in the region.Wu met with Palestinian President Mahmoud Abbas and other officials Tuesday, the first day of his ongoing Middle East tour.This was Wu's second visit to Palestinian territories this year, after which he will travel on to Israel, Egypt and France.

NAIROBI, Aug. 18 (Xinhua) -- The World Health Organization (WHO) on Thursday decried increased number of confirmed cholera cases in the Somalian capital Mogadishu, and growing reports of acute watery diarrhea in Kismayo and other crowded urban centers, saying an urgent multi-sector response to contain the spread of this highly contagious disease is being mounted.The UN health agency said has confirmed cholera in Banadir, Bay, Mudug and Lower Shabelle regions and the number of acute watery diarrhea cases has increased dramatically in the last few months.WHO Representative for Somalia Marthe Everard said combination of poor sanitation conditions, a shortage of safe water, overcrowding and high malnutrition rates, creates the perfect combination for infectious diseases, such as cholera and pneumonia, to spread and increase the number of deaths. "For the last few years, a network of health workers reporting to the early warning system is in place, however they report through a health facility or mobile clinic. Yet the large numbers of displaced people in Mogadishu are making it more difficult to record the various diseases," Everard said in a statement issued in Nairobi. "We urgently need more mobile clinics that will provide basic health care services to the many displaced and who will strengthen the reporting on new outbreaks. This is critical to our response and our ability to save lives."According to WHO, about seventy-five percent of all cases of acute watery diarrhea are children under the age of five.Since January this year, 4,272 cases of acute watery diarrhea/ cholera have been reported in Banadir Hospital in Mogadishu alone. However, at this stage most of the cholera cases in the various regions are contained and under control. "Our major concern is to monitor and detect new disease outbreaks in the many informal settlements set up by internally displaced people in and around Mogadishu", says Everard.Although cholera is endemic in the country, the last major cholera outbreak was in 2007 with an estimated 67,000 cases.WHO said recent efforts to cholrinate the water supply of Mogadishu, along with efforts to improve hygiene and sanitation have prevented a serious outbreak but with the large influx of some 100,000 people alone this year into Mogadishu, bringing the total number of IDPs in the capital to an estimated 470,000, many are living in overcrowded settlements, there is an acute shortage of safe water and adequate sanitation. "There is no need for a child to die of diarrhea, yet this is tragic reality for a Somali child, who is acutely malnourished. It is a lethal combination." said Rozanne Chorlton, UNICEF Representative for Somalia. "These types of diseases can be prevented and treated quickly, but to save children's lives we need to make sure safe water, sanitation and hygiene along with early access to primary health care, are an integral part of our emergency response."WHO said partners in the health and water and sanitation sectors are currently preparing for a potential 100,000 cholera cases including 80,000 moderate cases and 20,000 severe cases.Emergency diarrheal disease kits made up of medical supplies such as syringes, infusions, and oral rehydration fluids (ORS), already prepositioned by UNICEF and WHO have been sent to 13 hospitals.An additional 200 diarrheal disease kits, each able to treat 100 severe cases and 400 moderate cases are being procured and should be in Southern Somalia in the next few weeks, it said.In addition, WHO said, the case management of severe dehydration with and without malnutrition is being strengthened and focus is now on mobilizing a network of already trained community health promoters to move from door to door with health hygiene education messages. "Health posts will be stocked with essential medicines and ORS to identify and promptly treat patients. Many of Southern Somalia' s rural areas and urban centers rely on shallow wells, which unless protected or treated with chlorine can serve as the perfect breeding ground for water borne diseases," it said.To respond to this threat and prevent a major outbreak, the UN health agency said partners in the water, sanitation and hygiene sector are scaling up their actions to target 1.5 million people across high risk areas of the south.Supplies of chlorine and essential items for hygiene and household treatment and storage of water are being distributed.Already 217 water sources are being chlorinated and 58 water point outlets benefitting 483,200 residents and internally displaced people in Mogadishu.In addition, household hygiene supplies, including water purification tablets, soap and buckets, enough for 48,000 families, are being distributed at existing feeding centers for malnourished children.Campaigns to educate families about the treatment of drinking water, safe disposal of waste and encourage hand washing with soap will also be scaled up in high risk communities.As part of the updated 2011 UN Consolidated Appeal for Somalia, an estimated 80 million U.S. dollars is needed for the health sector and 78 million dollars is required for the water, sanitation and hygiene sector.So far, each sector has respectively raised 30 percent and 37 percent of the required money.

SAN FRANCISCO, July 7 (Xinhua) -- Apple announced Thursday that over 15 billion applications have been downloaded from its App Store by more than 200 million Apple mobile devices users worldwide."Thank you to all of our amazing developers who have filled it with over 425,000 of the coolest apps and to our over 200 million iOS users for surpassing 15 billion downloads," said Phillip Schiller, Apple's senior vice president of worldwide product marketing, in a statement.Launched on July 10, 2008, Apple's digital application distribution platform has been growing at a fast speed. It took nine months to hit one billion downloads and five billion in June 2010. In January, Apple gave a 10,000-U.S. dollar App Store gift card to a user who downloaded the 10 billionth application.In Thursday's statement, the Cupertino, California-based company said it had paid developers 2.5 billion dollars to date.Apple's mobile market place is far ahead of Google's Android Market. At its annual I/O conference in May, Google said there had been 4.5 billion app installs so far. But Google said the growth of its mobile operating system and applications is accelerating with its store hitting another billion downloads every 60 days.Currently, Apple is in a legal battle against Amazon over the use of "Appstore," which the online retailer launched in March to sell mobile applications to Google's Android platform users.On Wednesday, a federal judge denied Apple's request to immediately stop Amazon from using the term "Appstore."Meanwhile, Amazon, Microsoft, HTC, Nokia and Sony Ericsson have filed complaints against Apple in Europe, seeking to get Apple's trademarks for "App Store" and "Appstore" invalidated.