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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597

Thanksgiving is almost here, and along with the turkey, stuffing and pumpkin pie are thousands of calories ready to weigh us down. While packing on the pounds is as much a Thanksgiving tradition as much as watching football and shopping, there are ways for you to have a healthy Thanksgiving without passing on turkey.First off, here is the caloric breakdown of traditional Thanksgiving favorites:4 ounces of turkey breast: 120 calories7-ounce scoop of mashed potatoes: 237 calories1 cup of green bean casserole: 239 calories1 dinner roll: 87 calories1 slice of cranberry sauce: 86 calories1 cup of stuffing: 210 calories1 slice of pumpkin pie: 316 caloriesYes, 1295 calories are a lot for one meal, but there are ways to quickly burn those extra calories.Here are ways to burn calories, based on WebMD's fitness calculator for a 180-pound person:1-hour bike ride for 12 miles: 492 calories1-hour run for 6 miles: 820 calories3-hour round of golf (carrying clubs): 1353 calories1-hour walk on elliptical: 410 caloriesEven four hours of shopping can burn 754 calories. So if you plan to shop and you opt to ride your bike or walk to various shops, burning most of your Thanksgiving calories is possible.The only question is, will you have enough energy to burn off the leftovers?If you're looking for additional tips, they can be found on the 1354

The Department of Justice announced indictments on Wednesday against four executives who were allegedly involved in a conspiracy to fix prices and rig bids for broiler chickens. Jayson Penn, Roger Austin, Mikell Fries, and Scott Brady were each charged with one antitrust charge in federal court. Penn is the President and Chief Executive Officer, and Austin is a former Vice President, of Pilgrim’s Pride, a chicken supplier headquartered in Colorado. Fries is the President and a member of the board, and Brady is a Vice President, of Claxton Poultry, a broiler chicken producer headquartered in Georgia.According to Pilgrim’s Pride, it provides 20% of all chicken consumed in the United States. Claxton Poultry says it produces 300 million pounds of poultry a year, and is a supplier for Chick-fil-A. The DOJ alleges that the foursome's actions caused chicken prices at restaurants and grocery stores to be impacted. “Particularly in times of global crisis, the division remains committed to prosecuting crimes intended to raise the prices Americans pay for food,” said Assistant Attorney General Makan Delrahim of the Department of Justice’s Antitrust Division. “Executives who cheat American consumers, restauranteurs, and grocers, and compromise the integrity of our food supply, will be held responsible for their actions.”The executives face a maximum sentence of 10 years, and a million fine, if convicted. Broiler chickens are chickens raised for human consumption and sold to grocers and restaurants. A request for comment has been left for Pilgrim’s Pride. 1584

The Centers for Disease Control and Prevention expressed concern on Monday as it released figures that show a significant portion of young Americans are at a high risk of developing type 2 diabetes. According to CDC findings, 1 in 4 young adults aged 19-34 and 1 in 5 adolescents aged 12-18 suffer from prediabetes. Those with prediabetes have elevated blood sugar levels, but have not reached the threshold to be considered diabetic. The report from the CDC stated that overweight young people were significantly more likely to have prediabetes. The report found that 25.7% of overweight adolescents had elevated blood sugar levels, compared to 16.4 of adolescents of normal weight. Those figures were even pronounced among young adults. 36.6% of overweight young adults were prediabetic compared to 16.6% of young adults with a normal weight. “The prevalence of prediabetes in adolescents and young adults reinforces the critical need for effective public health strategies that promote healthy eating habits, physical activity, and stress management,” said CDC Director Robert R. Redfield, M.D. “These lifestyle behaviors can begin early in a child’s life and should continue through adolescence and adulthood to reduce onset of type 2 diabetes.”The CDC expressed concerns that young Americans with prediabetes face significantly higher cholesterol levels, systolic blood pressure, abdominal fat and lower insulin sensitivity than those with normal glucose tolerance, which increased their risk of type 2 diabetes and other cardiovascular diseases. All told, 1 in 3 American adults are prediabetic. Another 1 in 4 adult American are diabetic anddo not know it.The CDC says that type 2 diabetes can be prevented or delayed with healthy lifestyle changes, such as losing weight, eating healthy food, and being active.In the last 20 years, the number of adults in the US with diabetes have doubled, according to CDC figures. Justin Boggs is a writer for the E.W. Scripps National Desk. 1998

The City of Chicago is suing actor Jussie Smollett after he failed to pay the city over 0,000 for the police investigation of his report of a hate crime attack, court documents show.The civil lawsuit, filed Thursday in Cook County court, comes after the actor refused to pay a 0,106.15 bill meant to cover the cost of police overtime during the investigation.Smollett was given seven days to reimburse the city, but the actor's attorneys said the demand was meant to 485

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