山东痛风如何治疗好(济南中医能治好痛风) (今日更新中)

Lawyers for President Donald Trump recently provided the special counsel's office with documents in an attempt to limit the scope of an interview between Trump and special counsel Robert Mueller, The Washington Post reported Monday.Two people familiar with the situation told the Post that Trump's attorneys are worried that the President could get into trouble during a lengthy interview with the special counsel, and therefore provided "written descriptions" of moments under investigation to limit some of the questioning.News of the attempt by Trump's attorneys came after a weekend where the President railed repeatedly?against the Russia investigation, implying the special counsel team is politically biased against him and saying the probe itself should never have begun.Additionally, John Dowd, a lawyer for Trump, said in a statement?on Saturday that he prayed Deputy Attorney General Rod Rosenstein would end the investigation. And sources told CNN on Monday that Trump is expected to hire Joseph diGenova, an attorney who has claimed people in the Justice Department and FBI are trying to frame the President.The comments prompted warnings from some Republicans, and despite further warnings about the consequences of trying to force an end to the probe, lawmakers?played down the need to take up special legislation to protect Mueller from the President.The Post cited one person as saying Trump has told aides he is "champing at the bit" for an interview with the special counsel.Trump?said in January that he wanted to speak, under oath, with Mueller, and Dowd said shortly after the comment that he would be the one to decide if the President would do so.CNN reported last month that Trump still wanted to sit for an interview with Mueller, despite concerns from his attorneys. Last week, a source confirmed to CNN that Mueller had subpoenaed the Trump Organization for business documents. 1993

LA MESA, Calif. (KGTV) — La Mesa Police are looking into a harassment claims after a disturbing video captured outside a local business circulated online.Police said they were aware of reports regarding Peter's Men Apparel, a local men's clothing retailer on La Mesa Blvd. Police told 10News they've received at least two crime reports — one for battery and one for lewd act in public — in regards to separate incidents at the store on Saturday, Jan. 18.The video that sparked outrage appeared to show a man sitting outside the store with his hands up a woman's shirt, according to the original post's caption. 618

Less parental warmth and a more harsh work environment affect how aggressive children become and whether they lack empathy and a moral compass, according to a new study.Researchers at the University of Michigan, University of Pennsylvania and Michigan State University studied 227 pairs of identical twins. They analyzed differences in the parenting that each twin experienced to determine whether the differences predicted the emergence of antisocial behaviors.The study found that the twin who experienced harsher treatment and less emotional warmth had a greater chance of showing aggression and a lack of empathy and moral compass.These characteristics are known as callous-unemotional traits."The study convincingly shows that parenting—and not just genes—contributes to the development of risky callous-unemotional traits," said Luke Hyde, U-M associate professor of psychology. "Because identical twins have the same DNA, we can be more sure that the differences in parenting the twins received affects the development of these traits."Parents of the twins completed a 50-item questionnaire about the home environment, establishing their harshness and warmth levels.The work, published in the Journal of the American Academy of Child and Adolescent Psychiatry, is the latest in a series of studies from Penn's Rebecca Waller, assistant professor of psychology, and colleagues using observation to assess a variety of aspects of parenting. "Some of the early work on callous-unemotional traits focused on their biological bases, like genetics and the brain, making the argument that these traits develop regardless of what is happening in a child's environment, that parenting doesn't matter," said Waller, lead author of the current study. "We felt there must be something we could change in the environment that might prevent a susceptible child from going down the pathway to more severe antisocial behavior."Waller says a potential next step to turn these findings into interventions for families trying to prevent a child from developing these traits or to improve troubling behaviors. "From a real-world standpoint, creating interventions that work practically and are actually able to change behaviors in different types of families is complicated," she said. "But these results show that small differences in how parents care for their children matters. Our focus now is on adapting already-successful parenting programs to include specific interventions focused on callous-unemotional traits as well."For more information, click here. 2577

LA MESA, Calif. (CNS) - The La Mesa Police Department will resume parking regulation enforcement citywide starting the second week of November.La Mesa suspended the issuing of parking tickets on March 17 due to the ongoing coronavirus pandemic.Starting Monday, Nov. 9, La Mesa police will issue written citations for vehicles parked in violation of posted street sweeping routes, metered parking restrictions, curb time limits, commercial zones and 72-hour parking limits.The city of San Diego temporarily suspended parking enforcement on March 16, limiting enforcement to holiday or Sunday regulations only. San Diego resumed parking regulation enforcement citywide on Oct. 15. 686

Last year's seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, then, people had inadequate protection against the flu.This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a new study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.This year's flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate professor at the University of Pennsylvania. Add to that, he said, "this could end up being a pretty bad flu season."Still, he said, "our best protection" against severe illness is getting vaccinated with the flu shot we have today.Finding answersEach year before flu season begins, a vaccine is made based on whichever virus strains are expected to circulate. The selected seed strains are distributed to vaccine manufacturers which then produce their formulations and make them available to health care professionals before the season begins.During the 2015-16 season, vaccine effectiveness was 47%, while for the previous 2014-15 season, effectiveness was just 19%, according to the CDC. While the overall effectiveness of last season's vaccine was 42%, it was only 34% effective against the H3N2 viruses that dominated the season.Vaccine effectiveness varies based on how well it matches the circulating virus strains. Sometimes, a vaccine corresponds to the predominant virus yet its effectiveness is still not what scientists would expect. Trying to understand which element of the vaccine failed is difficult.Hensley and his team began their investigation of last year's vaccine by looking at the seed strains that had been distributed to vaccine manufacturers. These seed strains had been propagated in chicken eggs, the common method used today."The sequences of these viruses are available and when we did an alignment to see what the sequence of these vaccines were compared to the viruses that were circulating, it became very obvious that there was this mutation," said Hensley.To see the effects of the mutation, the team next looked at how the immune systems of both animals and humans who'd been inoculated with an egg-based flu vaccine responded to the actual circulating viruses.The antibodies -- immune system proteins that fight invading pathogens -- elicited in both animals and humans failed to bind to and neutralize the flu viruses, Hensley and his colleagues found.While most vaccines in the United States are made in chicken eggs, a small fraction are produced in insects or mammalian cells, Hensley explained. (These are given to people with egg allergies.) He and his team compared immune responses in animals and humans who had received a cell-based vaccine -- in this case, Flublok made by Protein Sciences Corporation."And we found both animals and humans receiving that (cell-based) vaccine had superior antibody responses that could bind and neutralize these circulating H3N2 strains," said Hensley.Making a better vaccine"Most of the infrastructure to produce vaccines in the US is based on chicken eggs," said Hensley. There are good reasons for this, including the fact that egg-based propagation allows manufacturers to quickly produce large quantities of vaccine.While egg adaptations have always been a problem, beginning last year it had become a "huge problem," said Hensley. "As soon as you try to grow this virus in eggs, within a few hours, the virus will acquire this kind of mutation."This is not an easy problem to fix, he said. To produce vaccines in cells means "a very expensive process for companies to just change their overall manufacturing process," Hensley explained. "You can't really do that on the drop of a dime."Meanwhile, the same seed strains used last year are being used this year to make the current vaccine, said Hensley."This year may be especially difficult because, in addition to this egg adaptive mutation which was present last year, there's indication that the H3N2 viruses are actually evolving," said Hensley.Not only will the vaccine be a mismatch with the actual circulating viruses due to egg adaptation but the vaccine could also be a mismatch due to unexpected viral evolution.What kind of flu season is ahead?It's too early to speculate which viruses will become dominant in the United States over the course of the coming flu season, said Hensley, "but it's starting to look like it will be H3 viruses." H3 viruses are influenza A viruses."There are the A group of viruses and the B groups," said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. "The A groups are the ones that usually are responsible for large epidemics ... whereas the B flu strains usually smolder along. They always cause illness -- it can be just as severe as the A strains -- but they don't produce large outbreaks."Though last year's vaccine was mostly ineffective in thwarting the flu, it still prevented nearly 30% of hospitalizations that might have resulted, according to CDC calculations. For older adults, that rate was even higher, at 37%. Plus, the vaccine reduced outpatient visits by 42% last season.The CDC advises everyone 6 months and older to get a flu shot, as only injectable flu vaccines are recommended. More than 130 million doses of flu vaccine have been distributed so far this year and flu activity is still low across the nation.It's still early days, but experts believe we may be facing a tough season, and not only because of vaccine concerns.The reason?Australia had a tough flu season this year, with a total of 215,280 laboratory-confirmed cases and 504 flu-associated deaths reported to its National Notifiable Diseases Surveillance System as of October 13, government data show. According to a surveillance system report, adults over the age of 80 and children between 5 and 9 years old have been most affected."In general, we get in our season what the Southern Hemisphere got in the season immediately preceding us," Dr. Anthony Fauci, director of the United States' National Institute of Allergy and Infectious Diseases, said in an interview last month.An "intelligent guess," therefore, is that the Northern Hemisphere, like the Southern Hemisphere, will likely battle more cases of the viral infection, he said, though "with influenza, it is never 100%.""If H3N2 viruses dominate the US flu season again this year, vaccine effectiveness will likely be moderate to low again," said Hensley.Still, he said, everyone should get their annual flu shot."The other components of the vaccine, like H1N1 and influenza B, will likely provide excellent protection," said Hensley. "The vaccine will also likely prevent severe disease and death caused by H3N2 viruses, even though this component of the vaccine is mismatched."  6969

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