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SAN DIEGO (CNS) - Construction crews will close the northbound Interstate 5 off-ramp at Balboa Avenue Friday for a full weekend of work to make improvements to the off-ramp and its intersection with Balboa Avenue, according to the San Diego Association of Governments.The closure will take place from 9 p.m. Friday through 5 a.m. Monday, during which time construction crews will widen the off-ramp from one lane to two and add a traffic signal at the affected intersection. The signal will go into permanent operation on Monday when the ramp re-opens to vehicle traffic. The improvements will make it easier for motorists to access the future Balboa Avenue trolley station once it opens.The closure will necessitate lane reductions on Balboa and Garnet avenues between Mission Bay Drive and Moraga Avenue, according to SANDAG. Only one lane in each direction will be open to vehicle traffic throughout the weekend, although the schedule is subject to change.The weekend work is part of the .17 billion Mid-Coast Trolley Blue Line Extension, which includes a planned 11-mile extension of trolley service by MTS from Santa Fe Depot in downtown San Diego to University City. The extension will add trolley stops in Mission Bay Park, UC San Diego and Westfield UTC. SANDAG is receiving .04 billion in funding from the Federal Transit Administration to complete the project.The extension and related projects are intended to reduce traffic congestion as the county's population increases. Construction on the extension began in 2016 and is scheduled to be completed in 2021. 1582

SAN DIEGO (CNS) - An outbreak of leptospirosis, a contagious bacterial disease, has been reported in dogs in the region, the San Diego County Health and Human Services Agency announced Thursday.Since October, 34 confirmed and probable cases of leptospirosis have been documented among local dogs, primarily in the Hillcrest and Mission Hills areas. Several dogs required hospitalization and at least one was euthanized.Boarding at kennels that allow dog-to-dog interaction is a major risk factor, though some ill dogs only had contact with other dogs at dog parks. The kennels that were linked to cases notified the owners of all potential contacts of diagnosed cases and closed for at least two weeks for cleaning and disinfection.Signs of leptospirosis in dogs are varied and can include fever, muscle weakness, vomiting, diarrhea, loss of appetite, low energy and frequent urination, which may be bloody.No human cases have been linked to this outbreak in dogs, but anyone who develops fever, headache, muscle aches -- especially in the back and calves -- or other illness after contact with a sick dog should see their health care provider.This week, the county sent a health advisory to local physicians and veterinarians about the outbreak.Leptospirosis is a disease caused by various species of spirochete bacteria called leptospira. These bacteria can infect multiple species of mammals, including humans, dogs, rats, mice, raccoons, skunks and opossums. The bacteria are shed in the urine of infected animals and may contaminate food, water, soil or bedding. Dogs and people can get infected through direct contact with skin abrasions, mucous membranes or by drinking contaminated water."When dogs visit kennels and parks and play, lick and sniff each other, they are at risk of getting these bacteria," said Dr. Wilma Wooten, the county public health officer. "If your dog shows any signs, you should take it to your vet immediately."A vaccine is available to prevent leptospirosis in dogs, especially for those boarding in kennels and frequenting dog parks. 2076

SAN DIEGO (CNS) - Eight residents and two pets were displaced Tuesday when a fire caused by electrical failure broke out in a Grantville apartment building, authorities said.The noninjury blaze was reported shortly after 5:35 a.m. at a two-story apartment building on Reflection Drive, in The Village Mission Valley apartment complex off Santo Road and Friars Road, according to the San Diego Fire-Rescue Department.Crews arrived to find smoke and flames coming from the roof of one apartment building, SDFRD spokeswoman Monica Munoz said, adding that all residents were able to escape safely before firefighters arrived.Firefighters knocked down the flames and kept the fire contained to an apartment on the second floor, Munoz said. A time of knockdown was not available.One other apartment on the second floor and one apartment on the first floor sustained smoke and water damage, she said. There was also extensive water damage in the building's attic because of a broken water pipe.Fire investigators determined the blaze was caused by an unspecified electrical failure, Munoz said.The American Red Cross was called in to help the displaced residents arrange for temporary lodging.The fire caused an estimated 0,000 in damage to the structure and an estimated 0,000 in damage to its contents, Munoz said. 1323

SAN DIEGO (CNS) - A UC San Diego epidemiologist was named today to Time magazine's 2018 list of the 50 most influential people in health care.Dr. Steffanie Strathdee, associate dean of global health sciences at UCSD's School of Medicine, was recognized for her successful efforts last year to keep her husband, psychiatry professor Tom Patterson, from dying due to a drug-resistant bacterial infection the World Health Organization classifies as the world's deadliest.Strathdee urged the team of scientists and doctors to use an experimental treatment for the infection using bacteriophages -- small viruses that act as parasites to bacteria by infecting and neutralizing them."It's a great honor to be recognized for my efforts to bring phage therapy into the 21st century in North America, but it all started with my single-minded desire to save my husband's life, and it truly reflects a team effort," Strathdee said.The magazine's list honors people who "have changed the state of healthcare in America this year, and bear watching for what they do next."Patterson was the first American patient with a systemic infection to receive bacteriophage treatment, according to Robert "Chip" Schooley, the lead doctor on Patterson's treatment team. UCSD Health doctors have since treated five more patients with bacteriophages. Doctors cleared a patient of a years-long, chronic infection this year using the treatment, allowing the patient to receive a life-saving heart transplant, officials said.All six treatment regimens required emergency approval from the Food and Drug Administration."The saga of Tom's remarkable recovery -- and the incredible efforts of UC San Diego Health doctors and scientists, led by Steffanie and Chip, was a real-life medical drama," said UCSD Vice Chancellor of Health Sciences Dr. David Brenner. "There are few places in the world with the resources, talented people and collaborative spirit required to do what was done here, to save a man's life when every other tool of modern medicine was failing."The UCSD School of Medicine founded the center for Innovative Phage Applications and Therapeutics in June with the help of a three-year, .2 million grant from university Chancellor Pradeep Khosla. Strathdee and Schooley co-direct the center, the first of its kind in North America."IPATH builds upon what we've learned and will apply rigorous principles that span from bench to bedside to better understand the potential role for phage therapeutics in the treatment of patients with infections that cannot successfully be treated with currently available antibiotics," Strathdee said. 2628

SAN DIEGO (CNS) - Masked intruders threatened a couple with guns and slashed the male victim with a knife today during a daybreak residential robbery in a Corridor-area neighborhood.The 27-year-old man and 20-year-old woman awoke at their residence in the 3200 block of Bramson Place about 6:30 a.m. to find the thieves next to their bed, pointing guns at them and demanding valuables, according to San Diego police. One of the intruders held a knife to the man's throat, Officer Robert Heims said.During the robbery, the male victim suffered several cuts, Heims said.Details on the severity of the wounds were not released.The thieves stole an unknown amount and type of items from the couple before fleeing, according to police. 738

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