济南痛风发作过一次(山东皮下形成痛风石) (今日更新中)

Snapchat can't catch a break.Shares of the social media company plunged Wednesday after it changed its app again — only months after a previous redesign that ticked off users.Snap stock was down 7% in midday trading, putting it more than 15% below the price when it went public last year.Last year, Snapchat changed the app to differentiate between a user's personal friends and media superstars that a user follows. Many fans revolted. So did Wall Street.The latest changes appear to backtrack. On the same Discover page, some users now see a test that shows Stories from their friends as well as posts from celebrities and other "influencers" that they subscribe to."We are always listening to our community and will continue to test updates that we hope will give Snapchatters the best possible experience on our platform," a Snapchat spokesperson told CNNMoney in response to a question about the changes.Celebrities aren't pleased with Snap lately, either.Kylie Jenner bashed Snapchat in February. Her tweet criticizing the redesign — she called it "so sad" — caused the stock to tank. Jenner later took a literal baby step back toward Snapchat, posting videos of her infant daughter, Stormi, to the platform.)Related: The Kylie Jenner curse? Snapchat faces its defining momentAnd just last month, Rihanna attacked the company after an ad on Snapchat made light of a 2009 incident in which Rihanna's former boyfriend Chris Brown was arrested. He later pleaded guilty to beating her during an argument.The constant rejiggering of Snapchat has clearly annoyed lots of users, though, not just famous people. It's making investors nervous, too. And it couldn't happen at a worse time for the company.It's still not clear that Snapchat will ever be able to be profitable enough to live up to the hype before it went public. Snapchat rallied after its last "earnings" report, but investors still worry about slow user growth.In many respects, Snapchat's challenges are similar to those of Twitter — a company that never can seem to satisfy Wall Street. Twitter stock fell Wednesday even though the company reported revenue and profit that topped forecasts.Concerns about privacy for social media users have reached new heights since the Facebook/Cambridge Analytica data scandal.Of course, Facebook also owns Snapchat's fiercest rival, Instagram. Many investors worry that Snapchat won't ever top Instagram's user count, especially if Instagram keeps rolling out features similar to Snapchat's.Facebook will report its latest earnings, including Instagram user numbers, after the market closes Wednesday.— CNNMoney's Kaya Yurieff contributed to this story. The-CNN-Wire 2676

Several world leaders sent well wishes to President Donald Trump and First Lady Melania Trump after the president confirmed early Friday morning that he had tested positive for COVID-19.British Prime Minister Boris Johnson, who was hospitalized for a week after contracting the virus in April, offered his "best wishes" to the couple."My best wishes to President Trump and the First Lady. Hope they both have a speedy recovery from coronavirus," Johnson tweeted. 470

SHEBOYGAN, Wisc. -- A Sheboygan dad was arrested for OWI after his two toddlers fell out of his van and were seriously injured.Police said it happened Tuesday just before 7:30 p.m. near 8th Street and Indiana Avenue. A witness told police the two children fell out of the van as it went through an intersection. Officers were eventually able to identify the children who were one and two years of age.A short time later police located their father -- who said he was not aware they had fallen out of the van.He was then arrested for OWI and Child Neglect.One child was treated and released from a local hospital. The other child was transported to a Milwaukee area hospital for serious but non-life threatening injuries.  764

Special counsel Robert Mueller told a federal court Tuesday that former Trump national security adviser Michael Flynn has given "substantial assistance" to the Russia investigation and should not get jail time.Flynn has sat for 19 interviews with the special counsel and other Justice Department offices, and his early cooperation gave prosecutors a road map for their Russia investigation and may have helped to encourage others to cooperate, the filing states.The new details explaining how Flynn has helped the special counsel investigation will ratchet up the pressure on President Donald Trump, who has repeatedly attacked the Mueller probe as a "witch hunt." 682

ST. CLAIRSVILLE, Ohio (AP) — Robert Murray, who, as a leader of the largest privately-owned U.S. coal operator long fought federal regulations to reduce black lung disease, has died.A lawyer tells The Intelligencer/Wheeling News-Register that Murray died Sunday at age 80 at his home in St. Clairsville, Ohio.He had announced his retirement on Oct. 19 from American Consolidated Natural Resource Holdings Inc. as board chairman.The company sued unsuccessfully in 2014 over regulations to cut coal dust in mines to reduce black lung disease.No official cause of death was given.According to the Associated Press, recent reports stated Murray had applied for black lung benefits with the U.S. Labor Department in early October.The AP reported that the West Virginia Public Broadcasting and Ohio Valley ReSource confirmed the claim through an online portal maintained by the Labor Department.Murray stated on the claim that he was on oxygen and "near death," the AP reported. 980

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