北京血清尿酸512(北京能治痛风吗) (今日更新中)

WASHINGTON, Jan. 19 (Xinhua) -- New research published this week in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.The study, led by investigators with the Ohio State University Comprehensive Cancer Center, shows that overexpression of two genes called MET and EGFR causes the deregulation of six microRNAs, and that this deregulation leads to gefitinib resistance.The findings support the development of agents that restore the levels of these microRNAs. It offers a new strategy for treating non-small cell lung cancer, which is responsible for about 85 percent of the 221,000 lung-cancer cases and 157,000 deaths that occur annually in the United States. It also suggests that measuring the expression levels of certain microRNAs -- those controlled by the MET gene -- might predict which lung-cancer cases are likely to be resistant to gefitinib.Epidermal growth factor receptor (EGFR) is frequently overexpressed in non-small cell lung cancer, and this leads to uncontrolled cell proliferation. Gefitinib selectively inhibits EGFR activation and triggers cancer cells to self-destruct by apoptosis. However, non-small cell lung cancer cells inevitably develop resistance to the drug. The study reveals how this resistance occurs."Our findings suggest that gefitinib resistance that is caused by MET overexpression is at least partly due to miRNA deregulation, " says principal investigator Carlo Croce.

BEIJING, Oct. 26 (Xinhua) -- The central government allocated 935 million yuan (147 million U.S. dollars) Wednesday to areas hit by rain-triggered floods, the Ministry of Civil Affairs (MCA) said.The relief funds, jointly allocated by the MCA and the Ministry of Finance, will be used for disaster survivors to relocate, rebuild houses and buy daily necessities.The funds will also be delivered to the family members of the victims, according to the ministry.The funds will go to the flood-hit provinces of Shanxi, Henan, Hubei, Sichuan, Shanxi and Guangxi Zhuang Autonomous Region.The government already allocated 132 million yuan (20.6 million U.S. dollars) to disaster hit areas immediately after the floods happened in September.Rain-triggered floods and disasters left 97 people dead, 21 missing and 1.23 million affected in September in China's 11 provincial-level regions, and a total of 1.93 million people were relocated urgently to avoid further casualties.The disasters also caused an estimated 21 billion yuan (3.29 billion U.S. dollars) in direct economic losses, according to official data.

BEIJING, Jan. 4 (Xinhua) -- Senior Chinese leader Li Changchun on Wednesday called for more efforts to strengthen the Internet construction and management and promote a healthy online culture.Li, a member of the Standing Committee of the Political Bureau of the Communist Party of China Central Committee, made the remarks at a national conference of publicity officials.Li also urged the officials to work and fortify the leading status of Marxism in the country's ideological field, and to provide spiritual support for the economic and social development.Li Changchun (C), a member of the Standing Committee of the Political Bureau of the Communist Party of China Central Committee, addresses a national conference of publicity officials in Beijing, capital of China, Jan. 4, 2012.The publicity work should help create a favorable environment for the country's efforts to stabilize economic growth, regulate commodity prices, adjust the economic structure, improve people's livelihood, carry forward reform and promote social harmony, Li said.Moreover, Li called for efforts to deepen the reform and promote development in the country's cultural sector.

BEIJING, Oct. 25 (Xinhuanet) -- Steve Jobs, Apple's co-founder and former CEO, may be one of the great men who will still be influential after their deaths.The new biography of Steve Jobs is likely to be the top-selling book 2011 of Amazon.com Inc, an online book retailer, according to Amazon spokeswoman Brittany Turner Monday."It could very likely be our top-selling book of the year," Turner said in a statement cited by the Reuters.Steve Jobs, written by Walter Isaacson, former Time magazine managing editor, was landed on shelves in bookstores Monday.But its digital version was reported to be released late on Sunday on Apple's iBooks online store and Amazon's Kindle eBook store.Since its release, the biography, both electronic and physical versions, has performed very well in Amazon.It is the best-selling book on Amazon.com and the top-selling electronic book on the Kindle as well. According to the Reuters, Isaacson was asked by Jobs to consider writing a biography for Apple's former CEO in 2004, when Jobs was going to be operated on for pancreatic cancer.Then Isaacson had more than 40 exclusive interviews with Steve Jobs. The last such interview was on October 5, one week before the giant's death.

SAN FRANCISCO, Dec. 29 (Xinhua) -- The United States Patent and Trademark Office on Thursday published a patent application from Apple related to face and presence detection for iOS devices, which is expected to be one of the next chapters for mobile security.According to AppleInsider, a news and rumor website focusing on Apple, the patent is entitled "low threshold face recognition" which is a low-computation solution for quickly and accurately recognizing a user on iPhone, iPad, iPod Touch and MacBook.Patently Apple, a blog focusing on Apple's latest intellectual properties, said that iOS devices would acknowledge the presence of the potential user by turning on the display and then trigger a subsequent process for recognizing the potential user's face.Currently, most face recognition systems tend to be robust ones working in various lighting conditions, orientations, scale and etc., which will require computing resources and drain battery life. There are also security-type face recognition systems working under controlled lighting conditions which could be ineffective due to factors like proximity of the user to the camera.Google's latest Android 4.0 operating system, codenamed Ice Cream Sandwich, already features face detection. But it is reported that the feature doesn't always work and can be bypassed by using a photograph of the phone's owner.Apple's solution would reduce the impact of lighting conditions and biometric distortions on an image, said AppleInsider, citing the filing. Apple said it would rely on a "high information portion" of a human face, such as eyes, mouth or the tip of a user 's nose.The "likely presence" of a human face in front of the camera would be captured through an "orange-distance filter" which would also be used to detect the potential user's skin tone and measure the distance of their face from the camera.Meanwhile, iOS devices could also be set to recognize faces of multiple users, presenting each user with a personalized configuration.According to AppleInsider, the patent application was first filed by Apple in June, 2009.Analysts said that the proposed technology could be Apple's next big innovation as it has record of redesign and give its unique appeal to products that have not caught on with the general public.

来源：资阳报