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Maryland-based vaccine developer, Novavax, has received .6 billion from the federal government to complete late-stage clinical development; set up large-scale manufacturing; and deliver 100 million doses of NVX?CoV2373, its COVID-19 vaccine candidate, as early as late 2020.This is the largest vaccine deal to date with the Trump administration as part of their Operation Warp Speed, which is focused on making a COVID-19 vaccine and treatments available as quickly as possible.Novavax has not brought any of their developed vaccines to market. According to information on their website, they have developed several vaccines for infectious diseases, however they are all in various stages of development or clinical trials. These include vaccines for the seasonal flu and RSV. Other vaccines created by Novavax are not actively being developed or studied at this time, including ones for Ebola, MERS, and SARS.According to a statement from Novavax, the agreement with the federal government includes the company demonstrating being able to rapidly get manufacturing and large-scale production of the vaccine going once approved. Novavax hopes to conduct their late-stage clinical study with 30,000 subjects in fall 2020.An early-stage clinical study took place in Australia in May on 130 participants. Study results are expected at the end of July.“Today’s .6 billion investment supports the Novavax candidate, depending on success in clinical trials, all the way through to manufacturing 100 million doses for the American people,” said U.S. Health and Human Services Secretary Alex Azar.Regeneron Pharmaceuticals has also received 0 million through Operation Warp Speed on Tuesday, to make and supply its COVID-19 vaccine candidate, REGN-COV2. Their vaccine is currently in phase 2 and phase 3 clinical studies for the treatment and prevention of COVID-19.Regeneron has several vaccines on the market currently, including Dupixent, used to treat allergic diseases such as eczema, asthma and nasal polyps which result in chronic sinusitis, and Praluent, used to treat high cholesterol. 2101

Meghan Markle has chosen a modest white bridal gown designed by Givenchy's Clare Waight Keller for her wedding to Britain's Prince Harry at St George's Chapel in Windsor.GALLERY:?See photos of Meghan Markle's stunning wedding dressBritish Waight Keller is the first female artistic director of the French fashion house, and is a fitting choice for Markle, who identifies as a feminist.The details and designer of the wedding dress had been a closely guarded secret for months.The long-sleeved haute couture gown with a simple bodice features a graphic open bateau neckline that delicately frames her shoulders. Markle is also wearing a five-meter-long veil and a tiara over a loose bun.The silk tulle veil has a trim of hand-embroidered flowers, representing the flora of each of the 53 countries of the Commonwealth.The bride arrived at the chapel in a 1950 burgundy Rolls-Royce belonging to the Queen, a car the monarch used for her first official engagement.Waight Keller made history last year when it was announced she would be replacing Riccardo Tisci as Givenchy's artistic director. Today, the 47-year-old is one few women at the helm of a Parisian fashion house.The-CNN-Wire 1191

Michelle Obama's brother Craig Robinson has been named the executive director of the National Association of Basketball Coaches.Robinson is leaving his job as the New York Knicks' Vice President of Player Development and Minor League Operations, a position he's held since 2017, to take over for Jim Haney, who held the NABC position for 29 years.“I’m extremely honored and excited for this tremendous and vital opportunity,” said Robinson in a press release. “I’d like to thank the NABC, our Board of Directors, President Jamie Dixon, and the search committee for selecting me at such an important time for our membership, our players, and our game. I look forward to the challenges ahead.”Robinson is now the fifth executive director in the association's history.“Craig encompasses everything we were looking for and more in the next leader of the NABC,” said Dixon, the head coach at TCU and 2020-21 NABC President in the release. “Craig’s experiences as a decorated student-athlete, an accomplished coach, and a high-level administrator uniquely position him to lead our association during this crucial moment in time for basketball. Given his background, education, and values, we have exceeded expectations from when we started the search. We’re confident that Craig will be an ally for coaches from all levels of our sport, and will continue to strengthen the collaboration between the NABC and the NCAA, the NBA, high schools, grassroots organizations, and numerous other key stakeholders,” Dixon added. “I would also like to thank Glenn Sugiyama and DHR International for supporting our search process.”Robinson formerly served as the head basketball coach at Brown and Oregon State. 1701

Market sentiment is so fragile that news of an arrest is enough to set off a selling wave.The Dow plunged as much as 785 points on Thursday. The index was recently down about 400 points, or 1.3%. The S&P 500 lost 1.1%, while the Nasdaq fell 0.3%.The arrest of Huawei CFO Meng Wanzhou in Canada at the request of the United States renewed doubts about the US-China truce.The latest sign of tension between Washington and Beijing also sent shudders through global markets. Hong Kong's Hang Seng plunged 2.5% overnight, while European stock markets declined sharply as well. Germany's DAX nearly closed in a bear market, down nearly 20% from its January closing high.Companies like Apple (AAPL) and Boeing (BA) that have significant exposure to China fell sharply. Other trade-related stocks like Broadcom (AVGO) and Harley-Davidson (HOG) were also under pressure. Alibaba (BABA), the Chinese e-commerce giant, tumbled 3%. The Dow and S&P 500 have once again turned negative on the year. The S&P 500, down 9% in the fourth quarter, is on track for its worst quarter in seven years.The arrest of Meng -- the daughter of the founder of one of China's most important companies -- serves as a fresh reminder that the United States and China remain in a trade war, despite the ceasefire reached last weekend in Argentina. Tariffs already imposed remain in place and new ones loom if talks fail to result in a breakthrough or at least an extension within 90 days."This comes at a truly delicate time," Win Thin, global head of currency strategy at Brown Brothers Harriman, wrote to clients on Thursday. "We think this will force China to take a more aggressive and confrontational approach with the US."  1720

MENIFEE, Calif. — The family of the woman who allegedly shot three people at YouTube headquarters on Tuesday say they tried to warn police about a potential attack.The family of Nasim Aghdam also described her as a peaceful person."She was a nice person," Agham's brother, who asked his name not be used, said. "I mean maybe not today, but she never hurt any creature."Aghdam's family said her passion was preaching in favor of vegans and rallying against animal cruelty. In 2009, she was part of a PETA protest in San Diego.The family says she felt she reached the most people through her YouTube page, but her relationship with the company turned ugly when YouTube changed its filters and she began to lose followers and viewers. 759