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WASHINGTON, April 3 (Xinhua) -- In the largest study of its kind, researchers from a consortium led by the University of Pennsylvania School of Medicine, the University of Miami, and the Boston University School of Medicine, identified four new genes linked to Alzheimer's disease. The findings appeared Sunday in the current issue of Nature Genetics.Each gene individually adds to the risk of having this common form of dementia later in life. These new genes offer a portal into what causes Alzheimer's disease and is a major advance in the field.The study, conducted by the Alzheimer's Disease Genetics Consortium, reports genetic analysis of more than 11,000 people with Alzheimer's disease and a nearly equal number of elderly people who have no symptoms of dementia. Three other consortia contributed confirming data from additional people, bringing the total number of people analyzed to over 54,000. The consortium also contributed to the identification of a fifth gene reported by other groups of investigators from the United States, the United Kingdom, France, and other European countries.The study is the result of a large collaborative effort with investigators from 44 universities and research institutions in the United States, led by Gerard Schellenberg at University of Pennsylvania."This is the culmination of years of work on Alzheimer's disease by a large number of scientists, yet it is just the beginning in defining how genes influence memory and intellectual function as we age. We are all tremendously excited by our progress so far, but much remains to be done, both in understanding the genetics and in defining how these genes influence the disease process," Schellenberg said.Until recently, only four genes associated with late-onset Alzheimer's have been confirmed, with the gene for apolipoprotein E-e4, APOE-e4, having the largest effect on risk. The Nature Genetics studies add another four -- MS4A, CD2AP, CD33, and EPHA1 -- and contribute to identifying and confirming two other genes, BIN1 and ABCA7, thereby doubling the number of genes known to contribute Alzheimer's disease.
JERUSALEM, May 8 (Xinhua) -- Israeli researcher Jacob (Koby) Scheuer, from the Tel Aviv University (TAU) School of Electrical Engineering, has developed a nano-scale gyroscope, the Ha'aretz daily reported Sunday.Scheuer developed a new optic-fiber nano-sensor four years ago, along with an optic gyroscope that works in conjunction with the sensor. As he developed the devices, it occurred to him that his discovery could be harnessed to surgical needs, virtual reality, or communications, said the report."What we developed here is an optic gyroscope," Scheuer told Xinhua in a recent interview on Sunday, "like the others, but the breakthrough is that we found a way to measure rotation in a very, very small device using the optic sensor."Optic gyroscopes emit light when they rotate, and change its wavelength when there is any change in the speed of rotation, making it possible to measure velocity and position by the differences in light.Scheuer's gyroscope, however, is so small in comparison to the others commonly used in planes, trains and vehicles, that it can be used in cell phones or watches and does not need satellite connection like the ubiquitous Global Positioning System.The applications of this gyroscope and optic sensor are almost endless, as Scheuer puts it."It can be a pill that you swallow and can move through your body to take pictures or release drugs in a localized area," the researcher explained, "or it can be used by a doctor to operate on a patient who is thousands of kilometers away.""Our gyroscope has complete independent navigation capability, which the others don't have," he stressed.Though the new optic gyroscope works in theory, it still hasn't been tried in out in reality. "It will take some time until we can empirically demonstrate our work, I would say about three to five years," Scheuer added.Alongside the gyroscope, Scheuer continues to work on the optic sensor, whose applications can also be found in security, such as an information security system developed by Scheuer to safeguard online information that acts as a key bearer."When both parties have 'the key' it's virtually impossible to hack the information sent," Scheuer noted, terming the development as a "total paradigm change."
DAVOS, Switzerland, Jan. 27 (Xinhua) -- A policy of more trade and greater openness to the rest of the world has brought significant benefits to China and greater market opportunities to its trading partners, the head of the World Trade Organization says."I don't think there is any question that China joining the WTO has been a very good thing for China and for the WTO and its members," WTO Director General Pascal Lamy said in an interview with Xinhua.The WTO chief was expected to join the forum "China's Impact on Global Trade and Growth" on the sidelines of the World Economic Forum annual meeting held in this Swiss alpine town."In joining the WTO, China successfully underpinned a policy of what had been 20 years of progressive openness," Lamy said.Adherence to economic reforms through international commitments ensured that China would stay on the path of openness, he noted, adding that the policy has helped the country economically, politically and socially.Lamy stressed that China has done a "remarkable job" in reducing poverty, which is an important task for the country, along with registering double-digit growth, thus becoming the world's largest manufacturer and the second largest economy.Apart from enhanced market access with its trading partners and more equal treatment in global trade, WTO membership also has allowed China to gain access to the organization's dispute settlement system, Lamy said.According to a WTO report issued in December, as the world's biggest exporter, China ranks first in receiving anti-dumping (AD) investigations, with 23 new AD initiations directed at its exports in the first half of 2010.In recent rulings arbitrated by the WTO Dispute Settlement Body (DSB), China has won a poultry dispute against the United States, and a steel fastener case against the European Union.Being a WTO member, "China would have a seat at the table as negotiations commenced on the trade rules for the 21st century," Lamy said, referring to the decade-long Doha round of global trade negotiations aimed at building the next generation trading system.Even more importantly, for China, participation in the global system of rules and discipline greatly boosted investors' confidence and helped facilitate foreign direct investment in China, he said.On the other side of the coin, China's integration into the world trading system has given enormous driving force to the global economy and market opportunity to its trade partners.
BEIJING, Feb.14 (Xinhua) - Shanghai General Motors Co. will recall 2,806 imported Cadillac CTS vehicles in China to repair faulty track bars to prevent safety risks, China's quality watchdog said on Monday.The recall, which is set to begin on March 21, includes models that were produced between June 16, 2008 and April 20, 2009, the General Administration of Quality Supervision, Inspection and Quarantine said in a statement on its website.The statement said that the company would repair or replace the rear suspension track bars of the recalled vehicles because some nuts on the bars are likely to loosen and cause worn screw threads.This could lead to a loosened track bar under extreme conditions, which is unsafe when traveling fast, it said.The company is to contact car owners to provide free checks and repairs. Owners may also contact the automaker on its free phone service (telephone number: 8008201902) for more information and to make appointments.