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SAN DIEGO (KGTV) — The city could be heading back to square one in its quest to regulate short-term vacation rentals.On Monday, the San Diego City Council will decide whether to send its recently approved short-term rental regulations to a public vote, or scratch them altogether.In the summer, the council voted 6-3 to limit Airbnb-type rentals to primary residences. That essentially banned investors and owners of second homes from renting them out short-term.Airbnb launched a referendum that obtained enough signatures to send the decision back to the council, leaving the city those two options. "The people who own short-term rentals - they're San Diegans like you and me," said Jeff MacGurn, who owns a short-term rental in the Hillcrest area with his husband and signed the petition. "When it comes right down to it, what we want is a fair and reasonable compromise."But Ronan Gray, who heads Save San Diego Neighborhoods, said something has to be done to curtail short-term rentals in residential areas. He pointed to a City Attorney memo that says short-term rentals aren't allowed by municipal code and said the city should just enforce that code. "They're advertising houses in Pacific Beach as the ideal location for bachelor and bachelorette parties, so they're marketing it as a hotel," he said. The council meets at 12 p.m. Monday at City Hall.  1405

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

SAN DIEGO (KGTV) — Surveillance footage captured a man attacking a gas station customer in Kearny Mesa before fleeing.A 54-year-old man was paying for his coffee at the Mobil station at 8380 Clairemont Mesa Blvd. on Saturday just after 3 p.m., when the suspect began speaking to the man. Police said the suspect was not making any sense when he was speaking to the victim.Then for no reason, the man pulled a small wooden bat from a tool bag and began to hit the victim on the back of his head. He fled from the business, running southbound on Kearny Mesa Road, police say.RELATED: Surveillance video captures deadly crash in Chula VistaThe victim was taken to a local hospital where he was treated for a concussion, cut to his head, and broken finger.Police said the suspect was wearing a yellow construction helmet, black hooded sweatshirt with a yellow reflective vest over it, work gloves, dark pants, and work boots. He was holding a "Milwaukee" brand tool bag.The suspect was described as a white male in his 30s, with thin build, and a brown and red beard.RELATED: Surveillance cameras egging on more destructive teen pranks?If anyone has any information, they're asked to call San Diego Police at 858-495-7957 or Crime Stoppers at 888-580-8477. 1260

SAN DIEGO (KGTV) — Summer is in full swing, with plenty of opportunities for families to get out and enjoy San Diego.San Diego Pride kicks off this week, with the annual Pride Festival on Friday, featuring stage of live music and performances, community booths, games, and more. Then Saturday, the community lines University Ave. in Hillcrest for the annual Pride Parade.In Escondido, the Inspire Festival invites attendees to let their inner artists out with interactive art activities, live music, and delicious local wines and craft beer.MORE: Don't see anything you like? Check out our event calendar for even more local eventsThe annual OTL World Championships return to Fiesta Island on Saturday, continuing San Diego's longstanding summer tradition with plenty to enjoy along the coast.Here's a look at what else is happening around San Diego:THURSDAYSantee Summer Concert Series Where: Town Center Community Park East; Cost: FreeCheck out the sweet tunes of the Bill MaGee Blues Band during Santee's Summer Concert Series. The community event hosts free concerts over the summer complete with a weekly Food Truck Rally every Thursday.The Cado pop-up museum Where: North City; Cost: - (Thursday - Sunday) "The Cado" pop-up museum opens in San Marcos' North City development, bringing interactive art installations like the Ripe Room, Haas Hall, and The Pit Stop to guests who want to dig deeper into the fruit.FRIDAYPride FestivalWhere: Balboa Park; Cost: Free - 0Pride celebrates San Diego's LGBT community with multiple stages of music and dancing at the Pride Festival in Balboa Park. The family-friendly event also features community booths, games, beer gardens, art, and vendors.Marvel in the MoonlightWhere: Quartyard; Cost: Free - Enjoy an evening with "Captain Marvel" as UCSD hosts a screening of the hit film downtown. Families can enjoy a beer garden, food, and a dog run area for pooches. Anyone under 18 and anyone who shows up in costume can get into the event for free.SATURDAYInspire FestivalWhere: Escondido Heritage Garden; Cost: - Paint on a giant canvas, discover delicious wines from local wineries, sample craft beers, and let yourself go to live music as the Inspire Festival heads to Escondido. One ticket includes unlimited food and drink tastings, access to interactive art exhibits, and the festival's live entertainment.Pride ParadeWhere: Hillcrest Pride Flag at University Avenue and Normal Street.; Cost: FreeCheer on floats, marching bands, and colorful cars as they roll through Hillcrest in celebration of San Diego Pride. San Diego's largest single-day civic event celebrates the local LGBT community and headlines Pride weekend.lmperial Beach Sun & Sea FestivalWhere: Imperial Beach; Cost: FreeThe Sun and Sea Festival brings thousands to Imperial Beach every summer for a day of sandcastle competition, concerts, food and more. This year, the theme of the competition will be "Under the Sea," as world-class sculptors create magnificent works of sand art.SUNDAY66th Over-the-Line World ChampionshipWhere: Fiesta Island; Cost: Free to spectate(Saturday - Sunday) The 66th OTL World Championship returns to Fiesta Island Park for two weekends July 13 and 14, and July 20 and 21. The annual event, known for its color team names and characters, started locally in the 1950s and has since become a highlight of summertime in San Diego.Bayside Summer Nights: Harry Potter and The Half-Blood PrinceWhere: Embarcadero Marina Park South; Cost: - 1(Saturday - Sunday) The San Diego Symphony is getting into the Comic-Con spirit early with a two-night performance of music from "Harry Potter and the Half-Blood Prince" as the film is screened, part of the Bayside Summer Pops concert series.Vines & Vittles FestivalWhere: Webb Park, Rancho Bernardo; Cost: - Enjoy a Western-themed festival with plenty of wine and cultural performances and music, featuring the Shirthouse Band and Mariachi Victoria de San Diego. Families can sink their teeth into delicious ice cream, popcorn, and more treats and local artists will showcase "trading post" post wares. 4127

SAN DIEGO (KGTV) -- The County of San Diego has spent nearly million to support migrants after the federal government ended the Safe Release Program, according to county officials.Flights carrying between 120 to 135 people are now flying from Texas to San Diego to relieve the processing backlog in the Rio Grande Valley sector in Texas. That sector is 200 percent over capacity, according to acting San Diego Border Patrol Chief Doug Harrison. So far, 10News has confirmed at least two flights have arrived in San Diego. It is not clear how many migrants, if any, will ultimately need county support. This latest round of migrants from Texas are first processed through Border Patrol before Immigration and Customs Enforcement takes over the processing. ICE told Team 10 custody is determined on a "case-by-case basis."Organizations like the San Diego County Rapid Response Network along with the County have stepped in since the end of the Safe Release Program. The program provided asylum seekers resources like transportation until their scheduled immigration court appearance. In a federal lawsuit filed in April, the County blamed the federal government saying "the County has suffered" and the move has "unfairly shifted the... burdens to the County and its residents."RELATED: Border officials say migrants from Texas being transferred to San DiegoProjected county costs for supporting migrant services totaled more than .65 million. That amount was through May 3rd. Here is the breakdown:- ,014,570 for contracted health services through UCSD- 1,676 for Health and Human Services Agency staff salary/benefits- ,392 for County Department of General Services staff support- ,640 for interpreters- ,965 for contracted nurse- ,743 for County Public Safety Group's Office of Emergency Services staff support- ,045 for pharmaceuticals- ,103 for various supplies and equipmentAs of late Monday afternoon, Supervisor Dianne Jacob said the latest amount is actually closer to million. She released this statement to Team 10:“I am deeply concerned that flying in hundreds of migrant families will put an even greater strain on San Diego non-profits, agencies and taxpayers. Immigration is clearly the responsibility of the federal government, but now it’s sticking San Diego County with the bill. Since the opening of an emergency shelter downtown in October, the county has had to spend nearly million to screen and process some 14,000 asylum seekers. Local taxpayers should not be on the hook for this.”It is unclear how long the migrant flights from Texas to San Diego will last. 2624

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