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The first large head-to-head comparison of two opioid addiction medications found that, although they were equally effective in getting people off of high levels of opioids, users had a significantly more difficult time starting a regimen of naltrexone, compared with buprenorphine.Buprenorphine is commonly known by the the brand name Suboxone, and naltrexone is sold under the brand name Vivitrol.The study, published Tuesday in the Lancet, looked at 570 patients with opioid addiction at eight inpatient treatment centers across the country for 24 weeks. Half of the group was assigned to naltrexone and the other half to bupenorphine.Six percent of those enlisted to use buprenorphine were unable to start their treatment, whereas 28% of those assigned to naltrexone dropped out before starting the therapy. 824

The final countdown is on and everything has been meticulously planned down to the final detail.But there is one wild card that even the Queen herself cannot control: What will the weather be for Prince Harry and Meghan Markle's big day on Saturday, May 19?Since we are still 10 days out, it's still too early to make a definitive call on rain or give detailed predictions about the timing of any potential showers -- but we can look at the long-range weather models and get an idea of what the general weather pattern will be while the world's eyes are on England.May's weather is off to a perfect start, with clear skies and well-above average temperatures in London nearing 30? C (86? F), which has locals feeling the royal wedding fever.The average high temperature for May in London is 18? C (64? F), so this past week has felt downright summer-like.A change in the weather threatens to dampen spirits, however, with cooler temperatures and several bouts of rain moving through in the next week as we lead up to wedding weekend.Temperatures will plummet to below average with significantly more clouds and some rain in the forecast as a couple of low pressure systems move through the British Isles next week.Fortunately, the weekend looks like it could see a return of the milder air and potentially clearer skies as high pressure builds over the North Sea.According to the UK Met Office, the nation's weather forecasting service, "there is low confidence in the forecast for the rest of next week and the following weekend, but there are some signals that it may turn drier, more settled and somewhat warmer with light winds."The forecast for the day can, and likely will, change over the next week and a half. Weather forecasts more than a week out have considerably less skill than short-term forecasts of just a couple of days.Especially when dealing with a region that has rapidly changing weather conditions like Great Britain.A dry wedding day would fit in line with other recent royal nuptials, including those of Prince William and Catherine Middleton in April of 2011 and Prince Charles and Diana's in July, 1981, both of which avoided the damp and rainy conditions many associate with British weather. 2226

The City of Glendale plans to vote on adding a permanent American flag to the top of Thunderbird Mountain. The Glendale Chamber Military and Veterans Affairs Committee sent a proposal to the city council asking to erect a flag. The committee will also manage it. Thunderbird Mountain falls within a conservation park, which means it is to be left as is. The picnic tables, garbage cans, and signage are all a part of the city's master plan, which is why they are allowed in the park. "We want people to enjoy it but not to disturb the wildlife the plants and not erect any structures in the park either, at least if they're not part of the master plan," said Vice-Mayor Lauren Tolmachoff. She is one of the council members voting to hold off on the change. "Not everybody on the council felt there was a conservation national park because there are signs and roads, and I disagree with that," she said. "You know there are roads in national parks, but they are still to be preserved and protected."No word on when the council will take an official vote, but it will likely be before the end of June.  1153

The director of the Census Bureau says irregularities have been found during the numbers-crunching phase of the 2020 census. Thursday's announcement makes it less likely the statistical agency can meet a year-end deadline for handing in numbers used for divvying up congressional seats. The Census Bureau already was facing a shortened schedule of two and a half months for processing the data collected during the 2020 census — about half the time originally planned. “These types of processing anomalies have occurred in past censuses,” Census Bureau director Steven Dillingham said in a statement. “I am directing the Census Bureau to utilize all resources available to resolve this as expeditiously as possible. As it has been all along, our goal remains an accurate and statistically sound Census.”The Census Bureau wouldn’t say Thursday what the anomalies were or publicly state a new deadline for the apportionment numbers.Missing the Dec. 31 deadline for turning in the apportionment numbers would be a blow to President Donald Trump’s efforts to exclude people in the country illegally from being counted in the numbers used to determine how many congressional seats each state gets and how .5 trillion in federal spending is distributed.Once the president receives the numbers by the Dec. 31 deadline, the president has about a week or so from the start of the next Congress to transmit them to the House. If the Census Bureau delays turning in the apportionment numbers because of the processing problems, that transfer of the numbers could take place after President-elect Joe Biden takes office.Trump’s apportionment order has been found unlawful by three courts — in New York, California and Maryland. The Justice Department has appealed to the Supreme Court, which is hearing arguments at the end of the month. 1835

The day after a gunman who spewed anti-Semitic rhetoric allegedly?killed 11 congregants in a Pittsburgh synagogue, thousands mourned the dead, said their names out loud and proclaimed that hate wasn't welcome in their city.The crowd at the Jewish Family and Community Services of Pittsburgh's interfaith gathering and vigil spilled out of the Soldiers & Sailors Memorial Hall & Museum. Many stood in the drizzle outside during the ceremony.Less than two miles away, agents filed in and out of the site of the massacre: Tree of Life Synagogue, which houses three congregations. Authorities said Robert Bowers stormed the building early Saturday and killed the congregants gathered for Shabbat services in what the Anti-Defamation League has called the deadliest attack on the Jewish community in US history.At Sunday's service, the rabbis of the three congregations embraced after tearful tributes. Christian and Muslim leaders pledged to stand with members of the Jewish community. 1007