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The United Kingdom says it will be the first to conduct COVID-19 vaccine human challenge trials.It's different than other vaccine studies. People will be deliberately infected with the virus, which speeds up the research process.Pending approval, the process will start in January at a London hospital. It will require about 90 healthy young adults between the ages of 18 and 30.The group 1 Day Sooner has recruited from all over the world, including 3,000 Britons.“If the vaccine works, then ideally, people don't get infected and if people do, then they will be closely monitored and treated, but because these are young and healthy people taking part in the trial, I think, researchers feel comfortable doing so because the risks of death are on par with something like kidney donation for people who are young and healthy,” said Abie Rohrig with 1 Day Sooner.Before researchers test the vaccine, they'll do a characterization study. That's where volunteers are infected by getting a vaccine to determine the right amount of virus to give during the trial.Because of the risk, 1 Day Sooner is advocating for the entire process to be made public.Results could come in May. Even though that's likely after other COVID-19 vaccines are licensed, it's still important because we need billions of doses and because of the unique data human challenge trials provide.“Researchers can understand how the virus works in the human body. They can understand the biological markers of immunity. In fact, much of our understanding of other types of coronaviruses come from challenge studies that were conducted in the 1960s in Britain,” said Rohrig.Human challenge volunteers are paid and monitored for at least a year after. 1722
The star of the Netflix documentary "Tiger King" Joe Exotic sued the United States Justice Department Wednesday because they rejected his request for a presidential pardon.According to court documents obtained by CBS11 and Courthouse News, lawyers for Exotic, whose real name Joseph Maldonado-Passage, argued that the rejection isn't valid because Acting Pardon Attorney Rosalind Sargent-Burns didn't give his official request to President Donald Trump himself.According to the six-page complaint filed in federal court in Fort Worth, Exotic's legal team named Sargent-Burns because she allegedly never gave President Trump a formal recommendation, which according to the lawsuit, she's required to do.Currently, Maldonado-Passage is serving a 22-year prison sentence in Fort Worth after he was found guilty in April 2019 for animal cruelty and trying to hire someone to murder Carole Baskin, who's a big-cat rights activist.The complaint also names Donald Trump Jr. as a supporter, CBS11 reported. 1006
The U.S. Census Bureau says only a tiny percentage of records are affected by data irregularities that are putting in jeopardy a year-end deadline for turning in numbers used for divvying up congressional seats. However, released internal documents show the "high complexity" problems could push the release to February 2021. The Census Bureau told a congressional committee Thursday that the anomalies are being resolved as quickly as possible. House Democrats however say documents they obtained from Census sources, despite Trump administration stonewalling, show hundreds of thousands of records are affected.Fixing the irregularities could mean missing a Dec. 31 deadline for the Census Bureau to turn reapportionment numbers in to Congress. The internal Census documents shared by House Democrats show the data issues, which include several "high complexity" problems, could delay the once-a-decade report until February. Although the documents do not specify the extent of the larger issues, they do say incorrect handling of the issues could skew the count smaller or larger in some areas. They also say the Census Bureau estimates they need an additional 20 days for data processing. The bureau says the timeline remains in flux.The Census Bureau issued a statement asserting that "these kinds of anomalies and issues are expected and are similar to the Census Bureau's experience in prior decennial censuses." The Census Bureau Director acknowledged the issues in mid-November, more details and the delayed timeline are coming out now. The timeline is getting attention because it may or may not be after President Donald Trump leaves office on January 20. Trump has expressed interest in excluding unauthorized immigrants from the Census count. There have been challenges in court and questions about whether this could legally be done, and also whether it physically can be done by coming up with a reliable number to exclude. Three lower courts have blocked the directive from Trump saying it violates federal law that says the census should could the "whole number of persons" in each state. The Supreme Court just this week heard arguments in the case. They have not issued their ruling yet. 2215
The Sikh community is speaking out after a Sikh Canadian minister was asked to take off his turban while going through a TSA checkpoint at Detroit Metro Airport.The incident happened in April 2017. Navdeep Bains, Canada’s Minister of Innovation, Science and Economic Development, went through the TSA checkpoint once without any issues but was asked to go through additional screenings because of his turban."Once they realized my position, who I was, I was ultimately allowed to fly but for me this is an issue that speaks for discrimination and discrimination happens with many people," Bains said. The agency is now issuing a statement and the U.S. government is apologizing to Canada.TSA responded to the incident saying in part: 767
The Trump campaign has officially filed a lawsuit in Wisconsin's Supreme Court in an attempt to overturn election results in the state.The Wisconsin Elections Commission confirmed Joe Biden's victory Monday in the battleground state following a partial recount. Milwaukee and Dane counties finished their recounts over the weekend and results added to Biden's 20,600 vote margin over President Donald Trump.The president's campaign has repeatedly alleged fraud in the state's election, though it has not presented any proof. The election officials for both counties who did recounts said there was no fraud uncovered in the process.The WEC confirmation of the results opened a five-day window for the president's campaign to file a lawsuit.The campaign filed a lawsuit Tuesday morning, in an attempt to overturn results by disqualifying as many as 200,000 ballots."What we had is an abuse of the absentee process, dramatically in Dane and Milwaukee County,” said Jim Troupis, attorney for the Trump Campaign.The suit is specifically seeking to dismiss absentee ballots where the clerks' offices "inserted missing information,” people cast ballots "claiming Indefinite Confinement status" even If they "no longer qualified,” and absentee ballots "improperly cast or received at ‘Democracy in the Park’ events,” which were held in Madison.The lawsuit also targets many in-person absentee voters who the Trump campaign claims did not follow Wisconsin law which requires "voters submit a written application.""We introduce evidence in the proceeding we introduced evidence that they in fact followed the law. They in fact required appropriate application in advance of the in-person voting,” said Troupis.In a filing late Tuesday evening, Gov. Evers and his legal team issued a forceful rebuttal against the lawsuit: "President Trump’s Petition seeks nothing less than to overturn the will of nearly 3.3 million Wisconsin voters. It is a shocking and outrageous assault on our democracy. The relief he seeks is wrong as a matter of law, incorrect as a matter of fact, and mistaken as a matter of procedure. Indeed, he has sought relief in the wrong court and has refused to follow the proper steps under the statute that he himself acknowledges governs the appeal of recounts. And by focusing on alleged technical violations in only two counties, he has made plain 7 that his intent is not to fairly determine who Wisconsinites voted for to lead our country. He is simply trying to seize Wisconsin’s electoral votes, even though he lost the statewide election."Mayor Tom Barrett says Milwaukee conducted in-person absentee voting exactly like all the other counties in the state. Barrett addressed the Wisconsin Elections Commission meeting on Tuesday to voice his opposition to the Trump campaign's attempt to throw out those votes."They are challenging the entire election system in Wisconsin claiming entire groups of absentee by mail and absentee in person were not legitimate. And I would add they are only doing it in select counties. These claims are obviously an egregious attempt to discredit this fair election,” said Barrett.Wisconsin Election Commissioner and Republican Dean Knudson spoke out Tuesday afternoon in the commission meeting that he believes this lawsuit still proves Wisconsin has safe elections.“I am in a position to look at fraud in Wisconsin and I have yet to see a credible claim of fraudulent activity in this election. The Trump campaign has not made any claims of fraud in this election. The filing in, there is some disputes over matters of law,” said Knudson.The WEC has debunked previous claims for the campaign about fraud in the election process.The president's campaign lawsuit included four instances where it claims votes were counted illegally:Lawsuit claims municipal clerks were instructed to fill in missing information on returned absentee ballots based on their "personal knowledge" or "lists or databases."Lawsuit claims municipal clerks issued absentee ballots to voters without requiring written absentee ballot applications.Lawsuit claims election officials permitted voters who claimed to be indefinitely confined to "circumvent voter ID laws" without "meeting the requirements for that status."Lawsuit claims the city of Madison created "unlawful polling locations at over 200 parks and city locations" through its Democracy in the Park voting events. The suit claims that these locations were outside of the county's approved polling locationsRead the full petition below:2020AP1971 Pet for Orig Action (12!1!20) by TODAY'S TMJ4 on ScribdRead the supporting memo below:2020AP1971 Memo in Supp Pet. Orig Action (12!1!20) by TODAY'S TMJ4 on ScribdThis story was originally published by WTMJ in Milwaukee. 4761