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SAN DIEGO (CNS) - A fire broke out Wednesday morning at a duplex in Rancho Penasquitos, and responding firefighters confronted cluttered conditions in one of the homes in order to knock down the flames and search for residents, authorities said. 253

SAN DIEGO (AP) -- Eric Hosmer hit a historic shot that made San Diego the first team in the majors to launch grand slams in four straight games, and the Padres needed an unearned run in the 10th inning for a wild, 8-7 win over the Texas Rangers.The Padres swept the four-game, home-and-home series, with a slam in each one. Hosmer's go-ahead shot against Kyle Gibson with one out in the fifth inning bounced off the top of the right field wall and into the seats for a 5-2 lead.Earlier this week, Fernando Tatis Jr., Manny Machado and Wil Myers slammed the Rangers.The Padres' 5-2 lead would not last, as reliever Michel Baez gave up a three-run double to Danny Santana in the top of the 7th. Texas grabbed a 6-5 lead one inning later on a Jose Trevino RBI single.San Diego regained the lead in the bottom of the eighth inning, thanks to back-to-back homers from Ty France and Austin Hedges.Emilio Pagan was sent in to close the game in the top of the ninth, but Nick Solak tied the score at 7-7 with a solo shot to right center.The game went to the 10th inning, and after the Rangers were unable to score in the top half of the frame, Jake Cronenworth's single to center slipped past the glove of outfielder Scott Heineman, allowing Myers to score from second base for the victory. 1290

Samuel and Ronan Peterson will have an interesting story to tell for the rest of their lives, thanks to Daylight Saving Time.The infant twins — born overnight on Nov. 6, 2016 — have a strange twist to their ages because of the time change.According to Cape Cod Healthcare in Massachusetts, Ronan is the older twin despite being born 31 minutes after Samuel.How does that work?According to hospital officials, Samuel was born at 1:39 a.m. Eastern and when his twin Ronan was born 31 minutes later, the clock had reset to 1:10 a.m., instead of being 2:10 a.m., because Daylight Saving Time had come to an end.So, despite technically being 31 minutes younger, Ronan's official time of birth is listed as 29 minutes earlier than Samuel's.One of the hospital's maternity nurses, who has 40 years on the job, said she'd never seen anything like it.Seth Peterson, the boys' father, figured something strange was going to happen due to his wife Emily giving birth on the night of Daylight Saving Time's end."I said earlier that night that they were either going to be born on two different days or the time change was going to come into play," he said, according to Cape Cod Healthcare.Clint Davis is a reporter for the Scripps National Desk. Follow him on Twitter @MrClintDavis. Keep up to date with the latest news by following @ScrippsNational on Twitter. 1373

SAN DIEGO (CNS) - A 21-year-old woman who allegedly was drunk last weekend when she crashed her Lexus into a Lyft car at high speed on state Route 163 in Balboa Park -- killing a passenger in the Lyft vehicle and injuring the other two occupants -- was charged Friday with gross vehicular manslaughter while intoxicated and DUI causing injury.Alondra Selena Marquez of San Diego was headed south on the freeway about 2:30 a.m. Saturday when she rear-ended the Mazda sedan near Laurel Street, according to the California Highway Patrol.One of two passengers in the Mazda, 40-year-old Giao Pham of San Francisco, died at the scene of the collision.ORIGINAL STORY: 1 dead, 3 injured in crash along SR-163A 33-year-old San Leandro resident remains hospitalized with a traumatic brain injury, while the 27-year-old Lyft driver is hospitalized with injuries of unknown severity, according to Deputy District Attorney Laura Evans.Marquez, who faces 13 years and four months in prison if convicted, had a .19 blood alcohol content at the time of the crash, Evans said.Marquez also sustained injuries in the crash, and was jailed Wednesday upon her release from a hospital. She is being held on million bail and is due in court April 10 for a readiness conference.According to a GoFundMe site created for Pham's family, he was in San Diego on vacation with friends. He is survived by his parents, eight brothers and sisters, eight nieces and nephews, his partner John, and his dog Matty, according to the page, which has exceeded its ,000 goal. 1549

SAN DIEGO (CNS) - A COVID-19 vaccine trial sponsored by drugmaker Johnson & Johnson is slated to get underway soon in San Diego, and will include an estimated 2,000 participants at UC San Diego Health, it was announced Thursday.Up to 60,000 participants will be recruited from 10 different countries around the world as the San Diego portion of the trial, dubbed ENSEMBLE, gets underway Oct. 7, according to UCSD.The efficacy, safety and immunogenicity of the drug Ad.26-COV2.S will be tested via a randomized, double-blind, placebo-controlled study, in which half of the participants receive a single-dose injection of the vaccine and the other half receive a placebo. All participants -- who must be 18 years of age or older and in reasonably good health -- will be monitored for signs of infection and COVID-19 over the next two years, according to UCSD.Researchers are particularly interested in recruiting participants at increased risk of SARS-CoV-2 infection due to where they live, their age or personal circumstances, such as working in essential jobs like first responders, health care, maintenance, construction, grocery stores or assisted living facilities.The San Diego trial will also emphasize participation from the region's underserved communities, as communities of color have shown higher rates of COVID-19-related hospitalization and/or death.UCSD cited data from the county showing measurably higher infection rates in the South Bay, including in Chula Vista, Imperial Beach and National City.Susan Little, professor of medicine at UC San Diego School of Medicine and principal investigator of the UC San Diego trial, said, "Many communities of color are experiencing higher rates of hospitalization related to COVID-19 than are observed in white, non-Hispanic people. It is important that these communities are represented in COVID-19 vaccine clinical trials so that we understand if the vaccine will work well within these groups."For more information about participating in the trial at UC San Diego, go to www.covidvaccinesd.com or call 619-742-0433. 2087