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SAN DIEGO (KGTV) - Beginning Thursday, there will be intermittent closures on Balboa Ave. and Garnet Ave. due to construction. This work is part of the Mid-Coast Trolley Project.Crews will be dismantling the Balboa Ave. Railroad Bridge that extends from Garnet Ave. to east of I-5.The construction work will cause lane and ramp closures overnight through July. Here is what to expect: 402

SAN DIEGO (KGTV) – At least 10 people were arrested during demonstrations in downtown San Diego Wednesday night that were sparked by the grand jury decision in the Breonna Taylor case.ABC 10News learned there were initially two separate protests planned in the downtown area. Eventually, the two groups joined together.Protesters marched through downtown chanting and holding signs demanding justice for Taylor. The demonstration made its way to San Diego Police Department headquarters on Broadway.Shortly after 10 p.m., SDPD tweeted that there were acts of violence and vandalism and declared the protest outside headquarters “an unlawful assembly.”According to the tweet, the crowd was ordered to disperse or face arrest. In response to acts of violence & vandalism, the protest in front of the SDPD Headquarters building (1401 Broadway) has now been declared an unlawful assembly.Demonstrators are ordered to immediately disperse. If you do not do so you may be arrested. pic.twitter.com/coUlOTVZ6p— San Diego Police Department (@SanDiegoPD) September 24, 2020 ABC 10News confirmed with police that at least 10 people were taken into custody during the protest, but officials did not disclose what charges the arrestees face.Taylor, a 26-year-old emergency medical worker, was shot and killed by Louisville police officers during a botched drug raid on her home in March. The warrant used to search her home was connected to a suspect who did not live there, and no drugs were found inside.A grand jury in Louisville on Wednesday decided that no officers will face charges for Taylor's death.Prosecutors argued the two officers who fired at Taylor were justified in using force to protect themselves after they were shot at by Taylor's boyfriend.The officer who fired the fatal shot and another officer who fired his weapon at Taylor face no charges, but former Louisville Metro Police Department Detective Brett Hankison was indicted with three counts of wanton endangerment for firing shots that went through Taylor's apartment and into an adjoining unit.City News Service contributed to this report 2118

SAN DIEGO (KGTV) - Anyone touched by Alzheimer's knows how painful the disease is. "It's affected my family. It's affected most families. It's such a prevalent disease. As people get older, it becomes quite likely this will become an issue," said Paul Aisen, director of USC's Alzheimer's Therapeutic Research Clinic (ACTC).Aisen's team began their research in San Diego many years ago and teamed up with USC about four years ago. He's spent over 30 years trying to solve Alzheimer's mysteries and is leading the upcoming clinical trial.Aisen says the large-scale study is the culmination of decades of work from scientists worldwide."Our focus lately has been trying to alter the disease, prevent it, or significantly slow its progression. How should we do that? We think attacking amyloid early is the most promising approach," said Aisen. Researchers believe sticky amyloid deposits, which form on the brain later in life, start the Alzheimer's process. Aging, genetics, and lifestyle factors can all contribute to amyloid build-up.The worldwide clinical trial aims to target amyloid. A drug called BAN2401 will be delivered intravenously, designed to bind to the sticky amyloid. The binding neutralizes beta amyloid and helps "tag" it, so the immune system can recognize it and clear it from the brain. A previous phase 2 study showed that BAN2401 removes brain amyloid and possibly slows cognitive decline.They're seeking participants over 50 who are not yet showing symptoms of Alzheimer's but do have elevated amounts of amyloid on their brain. Researchers can determine that through a PET scan or spinal tap. "We think that the most promising approach of all is to take a vigorous attack on amyloid while the brain is still functioning normally. And we can see amyloid in people many years before they develop the symptoms of Alzheimer's."Investigators hope that by treating a patient with BAN2401 very early in the disease, before symptoms occur, it will significantly slow disease progression. "If we're successful, it will have a huge impact on human health," said Aisen. There will be 100 sites worldwide for the study, including major cities like San Diego and Los Angeles. Study participants will receive treatment for four years, given either the drug or a placebo. Results are expected in seven years, Aisen says. If you or a loved one wants to participate, learn more here.Screening will officially begin in May. 2438

SAN DIEGO (KGTV) — Businesses in the Gaslamp District were evacuated Saturday due to a natural gas leak. San Diego Fire crews evacuated several business in the area of Fifth Avenue and E Street in the heart of the Gaslamp District. All streets within a one block radius, from F St. to Broadway and Fourth Ave. to Sixth Ave., have been blocked off. Police are asking pedestrians and drivers to avoid the area.No injuries were reported. No estimation as to how long the businesses would remain evacuated was immediately available. 10News is monitoring this breaking news story. 583

SAN DIEGO (KGTV) — As hundreds of Regal Cinemas in the United States face the potential for closure, other movie businesses are thriving.Cineworld, the parent company for Regal Cinemas, tweeted Sunday, saying “We can confirm we are considering the temporary closure of our U.K. and US cinemas, but a final decision has not yet been reached. Once a decision has been made we will update all staff and customers as soon as we can.”Conversely, a locally owned San Diego theater is thriving during this time. Douglas Yeagley owns Cinema Under the Stars, a small, outdoor Mission Hills movie theater. The business is in its 29th year and has always been outside, a key factor in keeping them afloat during the pandemic.RELATED: Regal Cinemas reportedly preparing to close all U.S. theaters, including eight in San Diego“People are honestly kind of starving for some kind of safe entertainment. You can’t do live music, you can’t do anything like that, you have to be in your car or something like that to see a performance of some nature, so this particular works well because you are super safe here, open-air,” said Yeagley.He said they’ve had to change a few aspects of business, including cutting seats from 62 to 42 per showing, spacing seats out for social distancing, cleaning seats twice between each showing, and also requiring face masks when standing. Even with the changes, they sell out most nights.Yeagley said he’s been to a few indoor movies since the pandemic and noticed the lack of others inside the theater, noting that there are a few key factors keeping people away from the indoor movie setting. The indoor location is a large factor, but also the delay of the release of major pictures is keeping people away.“There’s got to be a reason to come to that movie and you have to have an interest in that movie,” he said.The announcement from Regal Cinemas comes shortly after the announcement that the release of the latest Bond film would be delayed from November of 2020 to April of 2021 and the filming of many major pictures is delayed.In San Diego County, indoor movie theaters are able to operate at either 25% capacity or 100 people, whichever is fewer. While the indoor movie industry is taking a hit right now, Yeagley said he expects it to bounce back eventually, however it will take time and could look different once it recuperates.“I think so because people like to escape and that’s what you do in a movie. You quit thinking about it, are present for two hours, focused on something. That’s enjoyable. I can’t imagine people not wanting that.” 2581

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