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WASHINGTON, Dec. 7 (Xinhua) -- The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.Their report, published on-line Wednesday in Gynecologic Oncology, suggests that this combination, ixabepilone and sunitinib, might offer a much needed treatment option for women with advanced ovarian cancer.Neither drug is approved for use in ovarian cancer. Ixabepilone is a chemotherapy drug that, like other taxane drugs, targets the microtubules and stops dividing cells from forming a spindle. It has been approved for use in metastatic breast cancer. Sunitinib, approved for use in kidney cancer, belongs to a class of tyrosine kinase inhibitors that stops growth signals from reaching inside cancer cells.When caught at late stages, ovarian cancer is often fatal because it progressively stops responding to the chemotherapy drugs used to treat it."Women die from ovarian cancer because their tumors become resistant to chemotherapy, so a drug that might be able to reduce that resistance -- which may be what this combination of agents is doing -- would be a boon to treatment of this difficult cancer," says study coauthor Gerardo Colon-Otero.The finding also highlights the importance of the role of a molecule, RhoB, that the researchers say is activated by the drug duo. It might be a potential biomarker that may help identify patients who might benefit from such combination therapy, the researchers say.

BEIJING, Dec. 11 (Xinhua) -- A draft regulation on school bus safety management was made public Sunday by the Legislative Affairs Office of the State Council, with the public invited to submit comments on it.The draft stipulates that local governments above the county level should take "overall responsibility" in school bus safety, and authorities of education, public security, transportation and product quality supervision should also properly perform their respective duties.The government will establish and improve a system of mandatory technical standards for the quality of vehicles used as school buses, the draft stated. Primary school students queue up to get on the school bus to go home after school in Deqing County, east China's Zhejiang Province, Nov. 21, 2011. Local government of Deqing County has invested 20 million yuan (3.14 million U.S. dollars) to order 79 school buses, which are specially designed for children with smaller seats and seat belts as well as bright yellow color to have better warning function. Among the 79 buses, 14 ones have truck-style front ends, and this appearance like a long nose can effectively reduce the impact force and better protect children's safety. Drivers of such kind of school buses are required not to exceed 60 kilometers per hour. Nearly 6,000 children from 25 primary schools have benefited from the operation of this kind of school bus in Deqing County.China issued a set of technical standards for school buses for primary school students last year, and the drafting of another standard for buses for the kindergartners is also underway.According to the draft, the government will adopt a license system for school bus operation.Vehicles that are up to school bus standards and with a unified appearance will be first in line to obtain approval from education authorities, and the draft also requires buses to register at the traffic administrative agencies before they can be used as school buses.Instead of compulsory annual safety checks, the draft would require school bus owners to renew their safety qualifications every six months.Drivers should also check the safety condition of the buses before each commute, the draft said.The draft asks schools and the school bus service providers to intensify safety management and maintenance and assign special staff on buses to look after students on board.

BEIJING, Jan. 26 (Xinhua) -- China will firmly stand together with African countries while unswervingly pushing forward Sino-African strategic partnership, no matter how the international environment changes, said Chinese Vice Foreign Minister Zhai Jun Thursday.Zhai made the remarks in a signed article on top Chinese political advisor Jia Qinglin's upcoming visit to Africa.Africa still faced enormous challenges against the backdrop of simmering global finance crisis, and turbulence encountered by several countries in western Asia and northern Africa, which dealt a blow to Africa's peace, stability and development, Zhai said, adding that some outside forces' intervention into Africa's internal affairs impeded the integration process among African countries.Within this context, there is stronger demand of African countries for stability, development, solidarity and independence, he said.The international community should pay more attention to Africa's voice and problems, respect its opinions, accommodate its concerns, protect peace, stability and development in Africa, and support Africa's independent settlement of issues in its own region, Zhai said.He said Jia's visit, first foreign trip paid by Chinese leaders in the Chinese Lunar New Year, will be of great significance in deepening Sino-African ties and cementing the solidarity and cooperation among developing countries, Zhai said.Jia will declare China's determination on developing Sino-African ties during the trip, he said.Enhancing solidarity and cooperation with Africa constitutes an important part of China's diplomacy, and will be the long-term strategic choice firmly pursued by China, Zhai said.

UNITED NATIONS, Oct. 28 (Xinhua) -- China's progress in meeting a development goal on children's health can serve as an inspiration to other countries working towards the same objective, Dr. Renee Van de Weerdt, chief of maternal, newborn and child health at the UN Children's Fund (UNICEF) told Xinhua in an interview Friday.Van de Weerdt said that "the example of China is very encouraging because it means it can be done, even in a very big country with a very big population."China is on track to meet the fourth Millennium Development Goal (MDG), one of the eight development targets that the international community has pledged to meet by 2015. MDG 4 requires that each country reduce its rate of mortality for children under age five to two-thirds of what it was in 1990.According to Van de Weerdt, most deaths of children under five take place in the first month of life. After the first month, the most prevalent causes of death are pneumonia and diarrhea.ACHIEVING THE GOAL WORLDWIDEThe international community has been doing "relatively well" in working towards achieving MDG 4, Van de Weerdt said.The UN Interagency Group for Child Mortality Estimation (IGME) stated in their 2011 Report on Levels and Trends in Child Mortality that the number of under-five deaths worldwide has dropped from more than 12 million in 1990 to 7.6 million in 2010."We really continue to see progress," Van de Weerdt said. "The number of children that die every year continues to drop so we are really pleased to see that progress. Unfortunately, the progress isn't sufficient to really be able to say that if we continue at this pace we would achieve MDG 4 by 2015."Some regions, according to Van de Weerdt, like Latin America and parts of Asia are making more headway towards the goal than others that are currently lagging behind.

BEIJING,Nov. 9 (Xinhuanet) – Yinghuo-1, China's first interplanetary spacecraft, is set to hitch a ride with Russia's Phobos-Grunt Mars mission in the early hours on Wednesday, after a two-year delay.A Zenit-2SB rocket will carry Yinghuo-1 and Phobos-Grunt into space from the Baikonur Cosmodrome launch site in Kazakhstan.It is China and Russia's first joint Mars operation and also marks China's first voyage to the Red Planet, China Great Wall Industry Corp said in a news release on Tuesday.Yinghuo-1 will work in orbit with Phobos-Grunt for more than 12 months in collecting data on the Martian atmosphere.Both spacecraft will travel for more than 10 months before entering Martian orbit. During the trip, Yinghuo-1's power supply, communications and temperature gauge will be controlled from the Russian craft, scientists said.Both craft will orbit the planet three times before decoupling. The 106-kg Yinghuo-1 will circle Mars in an elliptical orbit, while Phobos-Grunt will actually land on Phobos, one of the two Martian moons, and bring back soil samples to Earth."The collaboration with Russia will enhance China's ability in deep space exploration, improve spacecraft design and development, and promote planetary exploration," said an unnamed official with the corp, a subsidiary of the China Aerospace Science & Technology Corp. Russia's Lavochkin Research and Production Association signed a cooperation contract, based on an agreement between the Chinese and Russian governments, with China Great Wall Industry Corp in 2007.Yinghuo-1, with a two-year lifespan, also has its own scientific goals.These include analyzing the planet's magnetic environment and ionosphere (upper atmosphere), taking images of topographical features and studying gravity fields on the Martian equator.Pang Zhihao, deputy editor-in-chief of the monthly publication, Space International, said China's focus on the planet's upper atmosphere is significant.Twenty detectors have explored parts of Mars, but most of them have looked for traces of life or water or places suitable for setting up colonies, he said.But studying the upper atmosphere is also vital if humans are to live on the planet, he said.The mission was set for October 2009, but later postponed to this year to enhance the reliability of the project.Only the United States, the former Soviet Union and the European Union have succeeded in landing probes on Mars. Five are in operation, four belong to the US and one belongs to the EU.At least 21 probes sent to the planet have failed. The Shanghai Academy of Spaceflight Technology under the CASC, which designed Yinghuo-1 in 23 months, said that the satellite posed a major technological challenge as the furthest space destination for China before had been the moon. The moon's average distance from Earth is about 384,000 km. The distance between Mars and Earth, depending on orbits, ranges from approximately 55 million km to about 350 million km.Yinghuo-1 will have to endure periods in the freezing dark side of the planet.It underwent simulated tests that matched the Martian temperature, - 260 C.Because of the distances involved, the satellite cannot rely on ground control to adjust position. It will rely on its own onboard computer, scientists said.