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SAN DIEGO (KGTV) - PhaseBio, a company based out of San Diego and Pennsylvania, announced it would be starting a clinical trial for a drug that could help keep severe COVID-19 patients from needing a ventilator. “If you are infected with coronavirus and you’re admitted to hospital, we’re trying to catch those patients before they have a rapid decline and prevent intubation or other more severe complications of the coronavirus,” said Jonathan Mow, CEO of PhaseBio. The drug is called PB1046 and is a “novel, once-weekly, subcutaneously-injected vasoactive intestinal peptide (VIP) receptor.” It was originally being researched for use on patients with high blood pressure, said Mow. But they pivoted when they realized it might have properties that could help prevent acute respiratory distress syndrome (ARDS), a potentially deadly condition caused by the inflammation of the lungs due to the body’s immune response to the coronavirus. “We realized that the characteristics of our drug fit nicely to what we would want to control in the complications in coronavirus patients,” said Mow. The clinical trial will take place at 20 different locations and involve about 210 subjects who have been hospitalized and require oxygen, but have not been intubated. Mow said they hope to publish the results of the trial by the end of the year. 1345

SAN DIEGO (KGTV) - More than 2,000 people whose lives have been affected by breast cancer started the Susan G. Komen 3-Day walk in San Diego Friday.One year ago, Leslie Heiser got the news she never expected to hear: she was diagnosed with breast cancer. After a year of treatment, doctors have declared her cancer-free. What started as simple motivation to get through tough days turned into what she believes will be a life-changing experience.The walkers participating in the Susan G. Komen 3-Day event will cover 60 miles in three days. All are doing it for different reasons: some walking in memory of loved ones, others showing support for those battling cancer. Heiser is doing the walk with her sister.RELATED: Rare breast cancer comes with unusual symptoms“She’s just been there for me every step of the way. And my biggest cheerleader from treatment to surgery. Those moments when you really need someone you can depend on, rely on, my rock," said Heiser.Each participant raised more than ,000 to do the walk. The money will go towards cancer research and medical expenses for those fighting the disease. Giving all those involved a sense of camaraderie as they flood the streets of San Diego with signs of pink while sending positive vibes to those who see them.Heiser adds, “it’s really about the experience of sharing it with other survivors and other people who have been impacted by breast cancer. And give everyone a chance of survival and hope.”RELATED: Breast Cancer Awareness Month events held in San Diego 1535

SAN DIEGO (KGTV) -- New details are emerging after an infant was attacked by a pit bull in Logan Heights Monday night.Family members now say the dog broke free of its leash before running to the infant’s bouncy chair. The pit bull was reportedly startled by the chair, leading to the attack.8-week-old Jema Gonzales is said to be in serious condition and has so far had one surgery.RELATED: Baby severely injured by pit bull bite in Logan HeightsThe incident happened on Irving Avenue around 2:30 p.m. Monday. After the attack, paramedics took Jema to the hospital with lacerations to the face and possibly a punctured eye. Witnesses originally said the dog licked then bit Jema’s face. The dog’s owner reportedly had to pry the dog’s jaw off the baby.   777

SAN DIEGO (KGTV) - Neighbors renewed their concerns over jets rattling their neighborhood less than a week before the F-35 arrives at Marine Corps. Air Station Miramar.The same concerns from University City neighbors voiced in letters to Miramar date back to at least 2012, according to MCAS Miramar Director of Communications Capt. Matthew Gregory.READ RELATED: Neighbors concerned with F-35 coming to MCAS MiramarHe pulled out a map of San Diego County's air space. He pointed to a gray square and said that entire area over the base up to 10,000 feet is controlled by the Federal Aviation Administration.Right off the end of the flight deck sits University City, where tragedy struck more than a decade ago. An F/A-18 crashed after having engine trouble, killing four and destroying two homes.With the F-35 coming to MCAS Miramar next week, neighbors are concerned the single-engine jet poses a higher risk.Capt. Gregory says the aircraft is arguably safer, "it is much easier to diagnose any issues and fix those issues."Neighbors are also concerned where the F-35 will fly, "the goal is to have flights as much as possible follow the approved flight paths," San Diego Council President Pro Tem Barbara Bry said.She was referencing a map with different colored flight paths. The Marine Corps. stated that map is from 2005, and shows average flight paths based on 5,000 annual operations. They said the map is disproportional and it is solely meant to illustrate the average flight paths for land developers.That came as news to Bry, "I don't think the community understands that. They understand that these are the flight paths they will take."When it comes to noise, "the Navy and Marine Corps have been flying F-18s here in San Diego for the past 30-35 years, so it's going to be very noticeable when the F-35s get here and start taking off," Capt. Gregory said.He added the Navy flew more jets when they ran the base.Overall, the F-35s are expected to make the area slightly quieter.Neighbors are having a meeting later this month, where a representative from Bry's office as well as MCAS Miramar will be present. 2130

SAN DIEGO (KGTV) — President Donald Trump told reporters Saturday the United States may close its border crossings to contain the spread of the novel coronavirus.Speaking from the White House, the President said his administration was "thinking about" possibly closing the country's borders to guard against the spread of COVID-19."We have ports of entry that we are keeping open. And we're not talking about it, we're thinking about all borders," President Trump said Saturday, when asked of the country's border with Mexico. "But right now that's not a border as it pertains to what we're talking about here. This is not a border that seems to be much of a problem right now. We hope we won't have to do that."The President said the U.S. is banning travel to Iran in response to the outbreak in that country, and elevating travel warnings to regions of Italy and South Korea, adding that more U.S. cases are “likely.” So far there are about 60 confirmed cases of COVID-19 in the U.S.RELATED:Coronavirus: Everything you need to knowUC San Diego, SDSU cancel South Korea study abroad programs due to coronavirusSan Diego County now able to test for coronavirusSan Diego-based Olympic hopefuls undeterred by coronavirus threatSome Americans refusing to buy or drink Corona beer amid coronavirus outbreak, according to surveyCanada is currently dealing with 16 coronavirus cases: eight in Ontario, seven in British Columbia, and one in Quebec. As of Saturday, Canada says the country has tested for 498 possible cases. Canadian officials, like the U.S., say the risk to the country's residents is low. Mexico currently has four cases of the virus, as of Saturday. Two patients in Mexico are located in Mexico City and one in the northwestern state of Sinaloa. The fourth patient was reported in the city of Torreon in the state of Coahuila: a 20-year-old woman who had recently traveled to Italy.This week, Mexico President Andrés Manuel López Obrador said the COVID-19 virus "isn’t even equivalent to flu," adding, "“I repeat, according to the available information, it is not something terrible, fatal ... There shouldn’t be any yellow journalism, or exaggerations, to cause a mass psychosis of fear, of terror," the AP reported.Saturday, the U.S. reported the first death in the country due to the virus in Washington state. State health officials described the victim as a man in his 50s who had underlying medical conditions.The Associated Press contributed to this report. 2484