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CLEVELAND — Scientists at the Cleveland Clinic Lerner Research Institute have successfully reversed Alzheimer's disease in mice.According to a news release, the researchers reversed the formation of harmful plaque in the mice's brains by gradually reducing an enzyme called BACE1, improving their mental function.“To our knowledge, this is the first observation of such a dramatic reversal of amyloid deposition in any study of Alzheimer’s disease mouse models,” says Riqiang Yan, one of the scientists on the team. The study raises hopes that drugs aimed at this same enzyme will soon be able to treat Alzheimer's disease in humans. You can read the full study in the Journal of Experimental Medicine here. 735
Consumers are looking for greater protections for their personal and financial information in the wake of the Equifax data breach. Many have decided to take precautions and put their credit on ice: a credit freeze.A credit freeze aims to block anyone from opening new accounts in your name. The catch is that the block applies to legit inquires, too. So it's not a great idea if you're shopping for a home or an auto loan. But when you're not looking to take out any loans or open any lines of credit, it can be a financial lifesaver.The Equifax hack, in which the names, Social Security numbers, birth dates, addresses, and driver's license numbers of 143 million people were exposed, may create a new normal in which protections previously viewed as cumbersome -- like credit freezes -- are now a valued line of defense."A security freeze is the most effective measure against 'new account' identity theft, because it stops thieves from using the consumer's stolen information," says Chi Chi Wu, a staff attorney at the National Consumer Law Center.Here's what you need to know about freezing your credit:What is a credit freeze?A credit freeze limits who can see your credit report information. The goal is to prevent anyone from opening any new accounts. It doesn't damage your credit or stop your credit report from evolving by your own actions.Your credit information will still be released to your existing creditors and any debt collectors who may come calling.But, if you want to open new lines of credit, you'll need to lift the freeze first. This can be done temporarily, either for a set time or for a particular party, like a landlord or lender.The costs to freeze and lift the freeze on your credit vary based on where you live and for each credit reporting agency, but commonly range from to per agency.If you're a resident of certain states -- like Maine or South Carolina?-- it's free.In response to public outcry, Equifax announced that fees to freeze your credit will be waived for the next 30 days.But even that doesn't totally protect your information since your data isn't fully frozen until it is on ice at all three credit bureaus. The other bureaus have their own fees. It's also unclear whether Equifax would still charge you a fee to lift the freeze. The company did not immediately respond to request for comment.Consumer protection organizations like the National Consumer Law Center are further calling for Equifax to waive the fees for credit freezes at all three credit bureaus.How is it different from fraud alerts or other credit monitoring?The credit reporting companies do little to make getting a credit freeze easy: you have to ask each of them individually, pay a fee (usually) to put it in place, ask each of them specifically to lift the freeze and often pay another fee. That's because your data is the product that they sell to other people and companies. If you freeze it, it isn't as valuable.As such, they are more likely to offer you fraud alerts and other credit monitoring products. These are services that will let you know when someone is looking at your credit and may contact you about a new account opened in your name. It's helpful, but it is often after the fact."Equifax is offering something that it says functions like a credit freeze," says Mike Litt, consumer program advocate with US Public Interest Research Group. "The problem is that it is incomplete protection and it only lasts for a year. What we're recommending is that people don't bother with the package Equifax is offering and just place freezes with the three credit bureaus instead."Can I still get a credit card or loan?Sure. When your credit is frozen you can continue to operate your financial life just as you typically would. The only notable thing is that you will need to notify the credit bureaus to lift the freeze before you ask a lender to approve you for credit.If you are able to determine which credit agency your potential lender is using to run your credit, you can even save yourself some fees by just requesting the freeze to be lifted on that one.The reporting agencies tell you that this may delay a legitimate credit request.But for those who don't feel comfortable with the way the credit reporting agencies are handling their treasure trove of personal information, a notification to the agencies and day or so delay may be a fair price to pay for added security.The agencies advise you to plan ahead and lift a freeze a few days before actually applying for new credit.How do I freeze my credit?With millions of people feeling vulnerable after the hack and scrambling to secure their most important information, getting a credit freeze has been more difficult than usual in the past few days. Users on Twitter report trying again and again to secure credit freezes, with both the website and phone systems failing.Keep trying.To set up your own credit freeze, go to the freeze page at each credit agency's website individually: Equifax, TransUnion,?Experian.You will be asked to provide information. If you do not want to put your information into another automated computer system, you can call the agencies directly. Usually you are given a PIN number, which is your key to lift the freeze. Do. Not. Lose.In addition to being subject to your state laws, the cost may also vary by agency.Often there is no charge for victims of identity fraud to add or lift a security freeze. Rules and fees at TransUnion, Experian and Equifax are similar, with the exception of Equifax's being waived for the next 30 days. 5652

Critics are calling Sinclair's promos pro-Trump propaganda. Now the company is defending the initiative, and calling it something much more mundane: A "corporate news journalistic responsibility promotional campaign."Sinclair, America's largest operator of local TV stations, is in the spotlight after a controversial promo video went viral over the weekend.Some staffers say they're embarrassed by the promos and concerned about their own credibility as journalists. A few local anchors and reporters are even reacting publicly, risking the ire of management.But Sinclair senior vice president of news Scott Livingston is defending the promos as a "well-researched journalistic initiative focused on fair and objective reporting."In an internal memo obtained by CNNMoney, Livingston slammed what he called "misleading, often defamatory stories" about the company. (The full memo is below.)Last month, at Livingston's direction, anchors at Sinclair's stations were required to read a script decrying "fake stories" and biased news coverage. Some of the language echoes President Trump's anti-media messaging. And it's written to make it sound like the opinion of the local anchors, when in fact it's a mandate from management.Concerned journalists contacted CNNMoney about the promos last month. When the promos started airing, the Deadspin blog produced a video compilation of the exact same script being read by anchors across the country, reiterating the robotic and manipulative nature of the message. 1518
CINCINNATI, Ohio – The national “If You Give a Child a Book …” campaign will distribute over 165,000 books to kids in low-income households across the country this school year after raising 5,369 during its annual fundraiser this fall.The childhood literacy campaign is led by the Scripps Howard Foundation and supported by employees of The E.W. Scripps Company, members of the Scripps family and communities where Scripps does business in more than 40 markets across the country. The campaign helps Scripps fulfill its vision of creating a better-informed world.Beginning January 2021, each Scripps TV station and national brand will partner with schools and nonprofits in their communities to ensure the books go to children who need them most, whether they are learning in a traditional classroom setting, remotely or a hybrid of the two.Since the campaign’s first year in 2016, more than 352,000 new books have been donated to children facing poverty in communities served by Scripps businesses. With the additional funds raised through this year’s campaign, the total number of distributed books will surpass 500,000.The first ,000 raised during the campaign was matched through a generous gift from The Kroger Co. Foundation. Additionally, members of the Scripps family matched Scripps employee gifts toward the campaign and granted each Scripps station a match of ,000 toward their local campaigns.“Having access to books at an early age is an important predictor of a child’s success. In fact, kids who learn to read are more likely to graduate, to vote and to be civically involved,” said Liz Carter, president and CEO of the Scripps Howard Foundation. “That is why the need this year is particularly urgent, with the pandemic affecting access to books for many families. We are blown away by the generosity shown during such a historic year – it’s a true testament to Scripps’ commitment to the communities they serve daily and the collective impact we can achieve for the future of thousands of kids across the country.”Scripps businesses place high priority on giving back to their local communities, including raising more than million for food banks across the country in June.Learn more and donate at ifyougiveabook.com. 2254
Confirmed cases of COVID-19 worldwide surpassed 40 million on Monday morning, according to a database kept by Johns Hopkins University.The United States (8.1 million), India (7.5 million), Brazil (5.2 million) and Russia (1.4 million) lead the world with the highest numbers of cases.Worldwide deaths linked to the virus total 1.1 million worldwide. The U.S. continues to lead the world in deaths linked to the virus with 219,674.The grim milestone comes as case rates around the world are spiking, marking some of the highest daily totals of new cases since the disease began spreading. On Friday alone, 411,337 people around the world were diagnosed with COVID-19 — the most in a single day since the start of the pandemic.The U.S. appears to be among the main drivers of the spike in case rates around the world. After averaging a staggering 90,000+ new cases a day last month, India has made efforts to slow the spread of COVID-19 in recent weeks. Within the past few days, the U.S. surpassed India as the country with the highest rate of new cases, with an average of more than 60,000 a day.Infectious disease experts in the northern hemisphere warn that the coming weeks are vital in slowing the spread of the virus ahead of the winter months. Experts like Dr. Antony Fauci say that it will be much more difficult to stop the spread of COVID-19 as people move activities indoors during colder weather. 1415
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