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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906

Daisy Muniz works at the same elementary school she attended while growing up in Reedley, California. "I moved here from Mexico when I was five, and I've been in Reedley all my life," said Muniz. Reedley is a rural town in central California that has seen better days. Its unemployment level is more than triple the national average, but it's trying to flip the switch on its economic woes and take the city to new heights. "When I came on board, we actually were going through a pretty bad cycle," said city manager Nicole Ziba. "Had an unemployment rate of 33 percent. That means 1 out of every 3 people that you would run into was out of a job and looking for one. That's a pretty dire situation economically." The town is trying to parlay its history with aviation into a bright future above the clouds. "The reason we have a shortage is that the cost of getting your pilot certificate is so high that it prices a lot of people out of that market or out of even considering that career path," said Joseph Oldham, with the San Joaquin Valley Clean Transportation Center. It starts with their best and brightest. Jefferson Elementary has a new state of the art flight simulator, courtesy of Boeing. It's part of the company’s plan to inspire a new generation of pilots. Rose, a student at the elementary school, doesn't have her sights set on staying in Reedley forever. "Paris, Rome, Washington DC and Mexico," said Rose on places she'd live. If she decides to cash in on her new found skills, she won't have to leave the city limits to train. "They teach us ground school lessons, so everything from we need to learn about the physics of flying, to learning airports, airport diagrams, and then they teach us as well in the simulator class how to actually fly the plane. That gets us ready for when we go to the actual airport and fly the real thing," said Benjamin Jones, a student in the Reedley College. Reedley College has a flight training program offering a less expensive option for prospective aviators. It's all part of the city’s bid to become a pilot pipeline. "You hear a lot of kids, 'I want to be a fireman. I want to be a policeman.' Now that this is here, now they have, 'Oh, we could fly planes? we could be pilots?'" said Muniz. But even if the students don't become pilots, just having the simulator around presents new horizons. "It doesn't just open up the possibility for this, but now it's like opening their minds to, what else? What's out there? What more can I do?," said Muniz. 2528

"I thought he was crazy," said Dave Egeler about what his identical twin told him he was going to do to raise ,000 to help two charities dedicated to helping dogs rescued from neglect, dogfighting and other forms of cruelty. This Saturday, Dan Egeler, a retired lawyer and cancer survivor, is planning to run four full marathons in 24 hours. Egeler's goal is to get a lot of people to donate a little bit or a lot to help him get to his goal of ,000. The money will be shared between Waggin' Tails Dog Rescue and Bark Nation which helps dogs recover from the abuse they've been subjected to in dogfighting. Both charities are nonprofit organizations that are driven by volunteers who are dedicated to helping the dogs recover from any physical and mental injuries they've suffered. "Anyone who owns a dog knows they are unconditional in their love," Egeler said. "They provide a lot of joy and excitement in the family and they're just so great to have around so we love dogs."And everyone will be able to keep up with Egeler's progress that will begin Saturday at 1 o'clock in the afternoon because he'll be wearing a tracker.Egeler will start in Dexter and run through parts of western Washtenaw county and on a track at night. He'll end his marathons Sunday at 1 o'clock in the afternoon in Dexter.Click here to find out more about the race, the charities, and where to make a donation. "Obviously it's a strong stress on the body and I plan for that, but I gotta do this and I've got to complete four marathons in 24 hours," Egeler said. "And that's gonna be more of a mental challenge than a physical challenge." This story originally reported by Kimberly Craig on wxyz.com. 1709

LOUISVILLE, Ky. – The robotics lab at the University of Louisville is a lot like a toy shop. “You don’t feel like you’re working with them, more like you’re playing around with robots,” said Sumit Das, a researcher at the lab. For him, it’s a dream come true. “I was always tinkering with things and making new stuff and my parents always encouraging me to do new stuff and even if I failed, they would be like, ‘it’s ok, move on to the next project.’ So, it has always been a project after project after project,” said Das. But here’s the thing. He’s not playing around. Sumit and PhD student Shamsudeen Abubakar, who goes by Abu, are part of a research team building a robot to help people heal. “So, in my estimate, about 5 to 10 years, hopefully we’ll see them be able to work alongside nurses,” said Das. This is ARNA—the Adaptive Nursing Robot Assistant. ARNA is built to help nurses do their job. “So you push on this like a walker that elderly people use,” said Abubakar The robot can do a few things: monitor a patients vital signs, pick things up and bring them to a patient, and help them walk down a hallway. “This robot really has the potential to diminish the incident of patient falls,” said Cindi Logsdon, a nursing profesor at the University of Louisville. Patient falls are a big deal, and Logsdon knows. She’s a consultant on the project and was the Associate Chief of Nursing at the University of Louisville Hospital for almost 10 years. “A big reason that patients fall when they’re in hospitals is they try and get out of bed by themselves, or they try and reach something that they can’t reach, or they depend on the darn bedside table,” said Logsdon. According to the Agency for Health Care Research and Quality, between 700,000 and 1 million patients fall in hospitals each year. Everyone involved in the project is hoping the robot will make a big difference in the U.S. and abroad. “I’m from Nigeria which is a developing country and I think robotics offers an avenue to kind of, you know, not jump the steps in development but kind of close the gap,” said Abubakar. “If there are any of the basic sort of skills that a robot could take over in collaboration with the nurses, in partnership with a nurse, it frees up the nurse for more higher level activities,” said Logsdon. “It’s about how to assist them in doing tasks that can eat their time up,” said Das. I know what you’re thinking. Sure these robots may help us heal in the hospital, but what’s to stop them from becoming self-aware and destroying the human race? “I think that’s limited to fiction. I don’t think that’s going to be a reality as it’s shown in Hollywood. I wouldn’t be worried about that,” said Das. 2725

My Mom, the one and only, Maggie Griffin, passed away today. Hours ago. I am gutted. She was my best friend. She was my family. You knew her. She appreciated you guys so much. I’m shaking. I won’t ever be prepared. Her point of view. So unique. We just GOT each other. I’m so grateful you got to be part of her life. You loved her. I know it. She knew it. She’s irreplaceable. I’m telling you right now, I am not doing well with this. I’m rambling now. Sorry. It truly feels like the end of an era. Oh, and OF COURSE she went on St Patrick’s Day. I love you guys. KG 582

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