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WASHINGTON, April 11 (Xinhua) -- In the first clinical trial of gene therapy for treatment of intractable pain, U.S. researchers from the University of Michigan's Department of Neurology observed that the treatment appears to be able to provide substantial pain relief.In a study published online in the Annals of Neurology and seen on Monday, the researchers showed that the novel agent NP2 is safe and well-tolerated. In addition, measures of pain in the treated patients suggested that NP2 may provide a substantial analgesic effect.NP2 is a gene transfer vector that expresses the naturally- occurring opioid peptide enkephalin. In preclinical work in animals, David Fink, chair of the Department of Neurology, and his coworkers had demonstrated that injection of NP2 into the skin reduces pain in models of pain caused by nerve damage, inflammation or cancer.In the clinical trial, 10 patients with unrelenting pain caused by cancer were injected with the gene transfer agent in the area of skin related to the location of pain."The concept underlying this therapeutic approach is that injection of NP2 into the skin results in uptake into the nervous system and the production and release of a pain-relieving chemical in a controlled site in the pain pathway," says Fink. "In the study, patients who received the low dose of vector showed little reduction in pain; patients receiving the higher doses showed a greater than 80 percent reduction in pain over the course of four weeks following treatment."Fink's laboratory has been working on the use of modified herpes simplex virus-based vectors that are taken up by sensory nerves following skin injection to develop therapies for diseases of the nervous system for more than 20 years. Patents related to this technology have been exclusively licensed by Diamyd Medical, a publicly-traded Swedish biotechnology company that sponsored the trial, and the human-grade vector NP2 was produced by Diamyd, Inc, the U.S. subsidiary of Diamyd Medical.A phase 2 trial to compare NP2 to a placebo control has already been initiated under sponsorship from Diamyd.

BEIJING, May 10 (Xinhuanet) -- YouTube is adding more than 3,000 mainstream movies to its movie-rental service, media reports said Tuesday.Google Inc-owned YouTube is offering a mix of recent Hollywood blockbusters, independent and foreign movies for 99 cents up to 3.99 U.S. dollars each.The additions will push YouTube’s total movie rentals available to more than 6,000.In addition, hundreds of movies, including some offered before the latest launch, are available for free viewing as with other clips.“By expanding our content partnerships worldwide and stimulating the success of budding filmmakers, artists and entrepreneurs, we’ll ensure that YouTube remains the best place for the world to see and discover rich talent,” Salar Kamangar, head of YouTube, said.YouTube, which built a following by letting users post home videos and amateur clips, is counting on professionally produced content to draw more visitors and keep them on the site longer.YouTube users currently spend about 15 minutes on the site per day on average, compared with the five hours they spend on television, the company said.

BEIJING, May 11 (Xinhuanet) -- New retirees suddenly confronted with plenty of time on their hands might be happy to learn that reading keeps one mentally alert and abreast of current aff airs, says Ursula Lenz of Germany's working group of senior citizens' organizations, BAGSO.Growing old can present difficulties such as failing eyesight or problems concentrating, but experts encourage the elderly not to give up on reading and to adapt to their situation.From the perspective of health professionals, there are many advantages to reading books or newspapers for senior citizens.Reading helps the elderly keep a sharp mind. The ability to transform words into mental images is good for cognitive performance. Reading also improves vocabulary, language use and the ability to concentrate, according to Simone Helck from the Kuratorium Deutsche Altershilfe, an organization in Germany that helps promote and develop strategies for taking care of the elderly.So, what exactly happens in the brain when we read?"The brain builds new synapses, junctions between the neurons, when it's stimulated such as during reading," says Manfred Gogol, a physician and president of Germany's Society for Gerontology and Geriatrics.Gogol recommends reading books that deal with subjects that are of special interest to the reader. If a long novel seems like too much work, then try a novella or collection of short stories.But a prerequisite for reading is that any sight defect is corrected by an optician.In response to the needs of elderly people, publishers print books with large typefaces and bigger line spacing. Lenz says it is worthwhile asking for large print books in libraries and bookshops.But no matter what the reading matter is, another important aspect is being able to exchange opinions about a book with other people. Whether it's a society magazine, highbrow literature or a daily newspaper, there is always something to talk about.

SYDNEY, Jan. 25 (Xinhua) -- Huawei Technologies, on Monday asked a U.S. District Court to prevent Motorola from illegally transferring Huawei's intellectual property (IP) to Nokia Siemens Networks ("NSN"), officials of Huawei told Xinhua in Sydney, Australia on Tuesday.As a leading player in providing next generation telecommunications network solutions, Huawei took this action as NSN seeks to complete its 1.2 billion U.S. dollars acquisition of Motorola's wireless network business.Since 2000, Huawei and Motorola have had a cooperative relationship in the radio access network and core network businesses, where Motorola has resold Huawei wireless network products to customers under the Motorola name. During this period, Motorola was provided with products and confidential Huawei IP developed by Huawei's team of more than 10,000 engineers.Since the July 2010 announcement by NSN of its purchase of Motorola's wireless network business, Huawei has tried to ensure that Motorola does not transfer this confidential information to NSN.According to officials of Huawei, Motorola's failure to adopt measures sufficient to ensure that Huawei's proprietary information remains confidential has compelled the company to file for the appropriate legal protection of its rights.The officials said Huawei respects the rights of intellectual property holders and is equally committed to the protection of its own innovations and intellectual property.Nearly half of Huawei's 100,000 plus employees are engaged in research and development and Huawei allocates an average of 10 percent of all revenues to R&D annually. By the end of 2010, Huawei had applied for 49,040 essential patents on a global basis.

CHANGCHUN, Jan. 22 (Xinhua) -- Chinese Vice President Xi Jinping stressed political integrity as the most important criteria in electing Communist Party cadres, during his three-day inspection tour in northeast Jilin province, which ended Saturday.The standards of political integrity and professional competence, with the former being the most important, should be strictly observed in the upcoming election of the new term for Party Committee members at provincial, city, county and township levels, Xi, a Standing Committee member of the Communist Party of China (CPC) Central Committee Political Bureau, said.During his meeting with leaders of the provincial Party Committee and provincial government of Jilin, Xi said efforts should be made to reinforce the notion of putting people first and exercising the state power for the people among carders.Chinese Vice President Xi Jinping (2nd L front) talks with a staff member at a workshop of FAW car factory in Changchun, capital of northeast China's Jilin Province, Jan. 21, 2011. Xi made an inspection tour in Jilin from Jan. 20 to 22.While visiting a community Party organization, Xi also asked grass-roots Party organizations to give priority to building a closer bond with the public and serving the public.During his visit to several companies, including Changchun-based First Automobile Works, Xi called for efforts to develop technology-intensive industries and the manufacturing of high-end products to promote economic restructuring.He also visited flood-hit areas to observe the relocation of flood victims and reconstruction work. Jilin Province was hit by unprecedented floods last July and August.He asked local governments to rebuild flood-damaged homes as soon as possible and repair those destroyed water conservancy projects and encourage farmers to grow crops on flooded lands.